Physician
Hematology
Dr. Bruce A. Hug, MD
Bruce practices Hematology. Dr. Bruce A. Hug has written publications. He has 24 publications published with PubMed. The lastest publication is: 'Endothelial cells in physiology and in the pathophysiology of vascular disorders.'
Publications
- A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual src/abl tyrosine kinase inhibitor, on cardia...
- A phase I ascending single-dose study of the safety, tolerability, and pharmacokinetics of bosutinib (SKI-606) in healthy adult subjects.
- Effect of Ketoconazole on the Pharmacokinetics of Oral Bosutinib in Healthy Subjects.
- Fusion-protein truncation provides new insights into leukemogenesis.
- HDAC4: a corepressor controlling bone development.
- A chromatin immunoprecipitation screen reveals protein kinase Cbeta as a direct RUNX1 target gene.
- Cooperative function of Aml1-ETO corepressor recruitment domains in the expansion of primary bone marrow cells.
- Plasma cholesteryl ester-triglyceride transfer protein. The catalytic domain is a low molecular weight proteolipid.
- Long-range disruption of gene expression by a selectable marker cassette.
- The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation.
- Deletions within the mouse beta-globin locus control region preferentially reduce beta(min) globin gene expression.
- tbx6, a Brachyury-related gene expressed by ventral mesendodermal precursors in the zebrafish embryo.
- Properties of human follicular dendritic cells purified with HJ2, a new monoclonal antibody.
- Endothelial cells in physiology and in the pathophysiology of vascular disorders.
- Structure and function of the murine beta-globin locus control region 5'' HS-3.
- Intravenous temsirolimus in cancer patients: clinical pharmacology and dosing considerations.
- Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus.
- A single-dose, crossover, placebo- and moxifloxacin-controlled study to assess the effects of neratinib (HKI-272) on cardiac repolarization in healthy adult subjects.
- Oligomerization of ETO is obligatory for corepressor interaction.
- Pharmacokinetic profile of temsirolimus with concomitant administration of cytochrome p450-inducing medications.
- Disposition of desipramine, a sensitive cytochrome P450 2D6 substrate, when coadministered with intravenous temsirolimus.
- ETO interacting proteins.
- Pharmacokinetics of oral neratinib during co-administration of ketoconazole in healthy subjects.
Schools
Washington Univ In St Louis Sch Of Med
Doctors Specialties
- Clinical Pathology
- Hematology
Accepted Insurances
Education
-
University of Pennsylvania Health System
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