Associate Professor of Medicine, Massachusetts General Hospital
Infectious Disease
George Jacoby
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George Jacoby works in the field of Infectious Disease. George Jacoby is a published doctor and has 53 publications published. The lastest was: 'Functions of a GyrBA Fusion Protein and Its Interaction with QnrB and Quinolones.'
Publications
- The Protective Effect of Qnr on Agents Other than Quinolones that Target DNA Gyrase.
- Functions of a GyrBA Fusion Protein and Its Interaction with QnrB and Quinolones.
- Plasmid-mediated quinolone resistance.
- In vitro Susceptibility of Characterized β-Lactamase-Producing Strains Tested with Avibactam Combinations.
- In Memoriam: Robert C. Moellering, Jr.
- QnrS1 structure-activity relationships.
- Mutational analysis of quinolone resistance protein QnrB1.
- Induction of plasmid-encoded qnrS1 in Escherichia coli by naturally occurring quinolones and quorum-sensing signal molecules.
- Phylogenetic Analysis of Chromosomally-determined Qnr and related Proteins.
- Quinolone Induction of qnrVS1 in Vibrio splendidus and of Plasmid-Encoded qnrS1 in Escherichia coli : Mechanisms Independent of the SOS System.
- Citrobacter spp. as a source of qnrB alleles.
- Structure of QnrB1, a plasmid-mediated fluoroquinolone resistance factor.
- Tackling antibiotic resistance.
- Cold shock induces qnrA expression in Shewanella algae.
- vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium.
- Updated functional classification of beta-lactamases.
- Transferable quinolone resistance in Vibrio cholerae.
- Plasmid-mediated quinolone resistance: a multifaceted threat.
- oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.
- Comment on: Redefining extended-spectrum beta-lactamases: balancing science and clinical need.
- Temporal appearance of plasmid-mediated quinolone resistance genes.
- Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period.
- SOS regulation of qnrB expression.
- AmpC beta-lactamases.
- Mechanistic and structural analysis of aminoglycoside N-acetyltransferase AAC(6')-Ib and its bifunctional, fluoroquinolone-active AAC(6')-Ib-cr variant.
- qnr Gene nomenclature.
- Human Salmonella and concurrent decreased susceptibility to quinolones and extended-spectrum cephalosporins.
- An ancient nova shell around the dwarf nova Z Camelopardalis.
- Prevalence in the United States of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme.
- The worldwide emergence of plasmid-mediated quinolone resistance.
- Plasmid-mediated quinolone resistance in non-Typhi serotypes of Salmonella enterica.
- Identification of extended-spectrum, AmpC, and carbapenem- hydrolyzing beta-lactamases in Escherichia coli and Klebsiella pneumoniae by disk tests.
- qnrB, another plasmid-mediated gene for quinolone resistance.
- Beta-lactamase nomenclature.
- Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase.
- Mechanisms of resistance to quinolones.
- Interaction of the plasmid-encoded quinolone resistance protein QnrA with Escherichia coli topoisomerase IV.
- The new beta-lactamases.
- Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase.
- Role of beta-lactamases and porins in resistance to ertapenem and other beta-lactams in Klebsiella pneumoniae.
- Activities of newer quinolones against Escherichia coli and Klebsiella pneumoniae containing the plasmid-mediated quinolone resistance determinant qnr.
- Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States.
- Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China.
- Interaction of plasmid and host quinolone resistance.
- Prevalence of plasmid-mediated quinolone resistance.
- Regional occurrence of plasmid-mediated SHV-7, an extended-spectrum beta-lactamase, in Enterobacter cloacae in Philadelphia Teaching Hospitals.
- blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513.
- TEM-71, a novel plasmid-encoded, extended-spectrum beta-lactamase produced by a clinical isolate of Klebsiella pneumoniae.
- Mechanism of plasmid-mediated quinolone resistance.
- Plasmid-determined AmpC-type beta-lactamases.
- Central and sensory control of food intake in genetically obese mice.
- Effects of electroconvulsive shock on sexual behavior in male rats.
Doctors Specialties
- Clinical Psychology
- Infectious Disease
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