Associate Vice Chancellor and Professor, Medicine-Infectious Disease, University of Tennessee Health Science Center College of Medicine
Infectious Disease
Dr. James B. Dale, MD
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James Dale practices Infectious Disease. He went to medical school at University of Tennessee College of Medicine. He received awards:"Elected Member". James Dale is a published doctor. He published 99 publications, including: 'Multivalent group A streptococcal vaccine designed to optimize the immunogenicity of six tandem M protein fragments.'
Publications
- Protective immunogenicity of group a streptococcal m-related proteins.
- Group a streptococcus expresses a trio of surface proteins containing protective epitopes.
- Streptococcal Pharyngitis in Schoolchildren in Bamako, Mali.
- A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development.
- Vaccination against the M protein of Streptococcus pyogenes prevents death after influenza virus:S. pyogenes super-infection.
- In Memoriam: Gene H. Stollerman.
- Group A streptococcal vaccines: Paving a path for accelerated development.
- Progress toward a global group a streptococcal vaccine.
- Potential coverage of a multivalent M protein-based group A streptococcal vaccine.
- New 30-valent M protein-based vaccine evokes cross-opsonic antibodies against non-vaccine serotypes of group A streptococci.
- Progress in the development of effective vaccines to prevent selected gram-positive bacterial infections.
- Prevalence of rheumatic heart disease in children and young adults in Nicaragua.
- The NH(2)-terminal region of Streptococcus pyogenes M5 protein confers protection against degradation by proteases and enhances mucosal colonization of mice.
- Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes.
- Relationship between expression of the family of M proteins and lipoteichoic acid to hydrophobicity and biofilm formation in Streptococcus pyogenes.
- The importance of the group a streptococcus capsule in the pathogenesis of human infections: a historical perspective.
- Current status of group A streptococcal vaccine development.
- Temporal changes in streptococcal M protein types and the near-disappearance of acute rheumatic fever in the United States.
- Safety and immunogenicity of 26-valent group a streptococcus vaccine in healthy adult volunteers.
- Multivalent group A streptococcal vaccine elicits bactericidal antibodies against variant M subtypes.
- Safety and immunogenicity of a recombinant multivalent group a streptococcal vaccine in healthy adults: phase 1 trial.
- Progress in group A streptococcal vaccine development.
- Intranasal immunization with multivalent group A streptococcal vaccines protects mice against intranasal challenge infections.
- Serum opacity factor (SOF) of Streptococcus pyogenes evokes antibodies that opsonize homologous and heterologous SOF-positive serotypes of group A streptococci.
- Immunogenicity of a 26-valent group A streptococcal vaccine.
- Antibodies against a synthetic peptide of SagA neutralize the cytolytic activity of streptolysin S from group A streptococci.
- Mapping the fibrinogen-binding domain of serum opacity factor of group a streptococci.
- Protective efficacy of group A streptococcal vaccines containing type-specific and conserved M protein epitopes.
- Seven-year surveillance of north american pediatric group a streptococcal pharyngitis isolates.
- Age-associated differences in prevalence of group A streptococcal type-specific M antibodies in children.
- Prospects for a group A streptococcal vaccine: rationale, feasibility, and obstacles--report of a National Institute of Allergy and Infectious Diseases workshop.
- Anti-phagocytic mechanisms of Streptococcus pyogenes: binding of fibrinogen to M-related protein.
- Group A streptococcal pharyngitis serotype surveillance in North America, 2000-2002.
- Molecular mechanisms of adhesion, colonization, and invasion of group A streptococci.
- Dynamic epidemiology of group A streptococcal serotypes.
- Host cell specific adhesins of group A streptococci.
- M protein expression is not required for resistance to phagocytosis of type 18 group A streptococci.
- Serum opacity factor is a major fibronectin-binding protein and a virulence determinant of M type 2 Streptococcus pyogenes.
- Spa contributes to the virulence of type 18 group A streptococci.
- Intranasal immunization with recombinant group A streptococcal M protein fragment fused to the B subunit of Escherichia coli labile toxin protects mice against systemi...
- Analysis of the role of M24 protein in group A streptococcal adhesion and colonization by use of omega-interposon mutagenesis.
- Cloning, sequencing, and expression of a fibronectin/fibrinogen-binding protein from group A streptococci.
- Passive protection of mice against group A streptococcal pharyngeal infection by lipoteichoic acid.
- Differential effects of the streptococcal fibronectin-binding protein, FBP54, on adhesion of group A streptococci to human buccal cells and HEp-2 tissue culture cells.
- Recombinant, octavalent group A streptococcal M protein vaccine.
- Conversion of M serotype 24 of Streptococcus pyogenes to M serotypes 5 and 18: effect on resistance to phagocytosis and adhesion to host cells.
- A 28-kilodalton fibronectin-binding protein of group A streptococci.
- Protective and autoimmune epitopes of streptococcal M proteins.
- Phosphorylase-cross-reactive antibodies evoked by streptococcal M protein.
- Epitopes of group A streptococcal M protein that evoke cross-protective local immune responses.
- Lipoteichoic acid and M protein: dual adhesins of group A streptococci.
- Recombinant tetravalent group A streptococcal M protein vaccine.
- Streptococcal protective antigens (Spa): a new family of type-specific proteins of group A streptococci.
- New protective antigen of group A streptococci.
- Multivalent group A streptococcal vaccine designed to optimize the immunogenicity of six tandem M protein fragments.
- Epitopes of group A streptococcal M protein shared with antigens of articular cartilage and synovium.
- Epitopes of streptococcal M proteins that evoke antibodies that cross-react with human brain.
- Type-specific antibodies to structurally defined fragments of streptococcal M proteins in patients with acute rheumatic fever.
- Sequence and type-specific immunogenicity of the amino-terminal region of type 1 streptococcal M protein.
- Protective immunity evoked by locally administered group A streptococcal vaccines in mice.
- Opsonic antibodies to the surface M protein of group A streptococci in pooled normal immunoglobulins (IVIG): potential impact on the clinical efficacy of IVIG therapy ...
- Hyaluronate capsule and surface M protein in resistance to opsonization of group A streptococci.
- Protective and heart-cross-reactive epitopes of type 19 streptococcal M protein.
- Protective and heart-crossreactive epitopes located within the NH2 terminus of type 19 streptococcal M protein.
- The reemergence of serious group A streptococcal infections and acute rheumatic fever.
- Lipoteichoic acid-binding and biological properties of T protein of group A streptococcus.
- Group A and group B streptococcal vaccine development. A round table presentation.
- Cellular and biochemical responses of human T lymphocytes stimulated with streptococcal M proteins.
- Unique and common protective epitopes among different serotypes of group A streptococcal M proteins defined with hybridoma antibodies.
- Attachment of Streptococcus pyogenes to mammalian cells.
- Repeating covalent structure and protective immunogenicity of native and synthetic polypeptide fragments of type 24 streptococcal M protein. Mapping of protective and ...
- Pathogenesis of group A streptococci in mice and efficacy of locally administered streptococcal vaccines.
- Hybridoma antibodies against protective and nonprotective antigenic determinants of a structurally defined polypeptide fragment of streptococcal M protein.
- Human and murine antibodies cross-reactive with streptococcal M protein and myosin recognize the sequence GLN-LYS-SER-LYS-GLN in M protein.
- Identification of an epitope of type 1 streptococcal M protein that is shared with a 43-kDa protein of human myocardium and renal glomeruli.
- Group A streptococcal vaccines.
- Human cytotoxic T lymphocytes evoked by group A streptococcal M proteins.
- Monoclonal antibody to human renal glomeruli cross-reacts with streptococcal M protein.
- Streptococcal C5a peptidase is a highly specific endopeptidase.
- Expression of protective and cardiac tissue cross-reactive epitopes of type 5 streptococcal M protein in Escherichia coli.
- Comparison of the leader sequences of four group A streptococcal M protein genes.
- Heterogeneity of type-specific and cross-reactive antigenic determinants within a single M protein of group A streptococci.
- Erythrocyte binding properties of streptococcal lipoteichoic acids.
- Blastogenic responses of human lymphocytes to structurally defined polypeptide fragments of streptococcal M protein.
- Identification of a gene within a pathogenicity island of enterotoxigenic Escherichia coli H10407 required for maximal secretion of the heat-labile enterotoxin.
- Lymphocytes binding and T cell mitogenic properties of group A streptococcal lipoteichoic acid.
- Tyrosine phosphorylation of a 94-kDa protein of human fibroblasts stimulated by streptococcal lipoteichoic acid.
- Localization of protective epitopes of the amino terminus of type 5 streptococcal M protein.
- Protective antibody against a peptide fragment of type 5 streptococcal M protein cross-reacts with human heart tissue.
- Common protective antigens of group A streptococcal M proteins masked by fibrinogen.
- Comparison of adherence to and penetration of a human laryngeal epithelial cell line by group A streptococci of various M protein types.
- Fusobacterial cerebritis and myelitis presenting as acute paraplegia in an elderly man with congenital heart disease.
- Epitopes of streptococcal M proteins shared with cardiac myosin.
- Multiple, heart-cross-reactive epitopes of streptococcal M proteins.
- Protective immunogenicity and T lymphocyte specificity of a trivalent hybrid peptide containing NH2-terminal sequences of types 5, 6, and 24 M proteins synthesized in ...
- Stimulation of S-adenosylmethionine synthetase in human lymphocytes by streptococcal M protein.
- Streptococcal defenses against host immune attack: the M protein-fibrinogen interaction.
- Type-specific immunogenicity of a chemically synthesized peptide fragment of type 5 streptococcal M protein.
Schools
University of Tennessee Memphis College of Medicine amp Surgery
Regional Med Center At Memphis
Doctors Specialties
- Internal Medicine
- Infectious Disease
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- Blue Network E
- Network S
- Coventry Health Care of Tennessee PPO
- First Health (Coventry Health Care) PPO
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Simplifi
- United Healthcare
Awards
- Elected Member
Education
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University of Tennessee -
University of Tennessee College of Medicine
Hospital
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University of Tennessee Medical Center
Drug Facts
| NPI NUMBER | 1336132265 | |
| NPPES Provider LastName | DALE | |
| NPPES Provider FirstName | JAMES | |
| NPPES Provider ZIPCode | 228351000 | |
| NPPES Provider State | VA | |
| Specialty Description | Internal Medicine | |
| Total Claim Count | 16241.0 | |
| Distinct Opioid Count | 10.0 | |
| Opioid Claim Count | 1198.0 | |
| Percent Opioid Claims | 7.38 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1336132265 |
| Last Name Of The Provider | DALE |
| First Name Of The Provider | JAMES |
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