Physician
Pediatric Rheumatology
Dr. Robert A. Colbert, MD
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Robert Colbert is an expert in the field of Pediatric Rheumatology. He attended University of Rochester School of Medicine and Dentistry. Robert Colbert is also published. He has 84 publications published. The lastest publication: "HLA-B27 subtype polymorphism and CTL epitope choice: studies with EBV peptides link immunogenicity with stability of the B27:peptide complex.'
Publications
- American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 Recommendations for the Treatment of Ankylosi...
- Development and retrospective validation of the juvenile spondyloarthritis disease activity index.
- The Concept of Axial Spondyloarthritis: SPARTAN and ASAS joint Statement in response to FDA's comments and concerns.
- Childhood arthritis and rheumatology research alliance consensus treatment plans for new-onset polyarticular juvenile idiopathic arthritis.
- Radiography Versus Magnetic Resonance Imaging (MRI) in Juvenile Spondyloarthritis: Is the MR Image Everything?
- Review: the interleukin-23/interleukin-17 axis in spondyloarthritis pathogenesis: th17 and beyond.
- Detection of enthesitis in children with enthesitis-related arthritis: dolorimetry compared to ultrasonography.
- HLA-B27 misfolding and ankylosing spondylitis.
- The IL-23/IL-17 axis in spondyloarthritis pathogenesis: Th17 and beyond.
- 17 and 23: prime numbers for ankylosing spondylitis?
- HLA-B27 alters the response to TNFα and promotes osteoclastogenesis in bone marrow monocytes from HLA-B27 transgenic rats.
- Altered PKR signalling and C/EBP? expression is associated with HLA-B27 expression in monocytic cells.
- Enhanced phosphorylation of STAT1 is dependent on PKR signaling in HLA-B27 expressing U937 monocytic cells.
- Biosimilars: The debate continues.
- Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade.
- Rheumatoid arthritis consensus conference; July 22-23, 2010: Clinical trial priorities and trial design issues.
- Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis.
- Healing the Syk through kinase inhibitors.
- Gene Expression Profiles from Peripheral Blood Mononuclear Cells Are Sensitive to Short Processing Delays.
- Early axial spondyloarthritis.
- Classification of juvenile spondyloarthritis: Enthesitis-related arthritis and beyond.
- HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats.
- Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis.
- Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
- HLA-B27 misfolding and spondyloarthropathies.
- The interleukin-23/interleukin-17 axis in spondyloarthritis.
- B-cell depletion in Wegener's granulomatosis.
- Gene expression analysis of macrophages derived from ankylosing spondylitis patients reveals interferon-gamma dysregulation.
- Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may pr...
- Evidence that the p38 MAP kinase pathway is dysregulated in HLA-B27-expressing human monocytic cells: correlation with HLA-B27 misfolding.
- HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications...
- T cells lacking immunoproteasome subunits MECL-1 and LMP7 hyperproliferate in response to polyclonal mitogens.
- Pediatric and heritable disorders.
- HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response.
- Nomenclature and classification in chronic childhood arthritis: time for a change?
- Enhanced intracellular replication of Salmonella enteritidis in HLA-B27-expressing human monocytic cells: dependency on glutamic acid at position 45 in the B pocket of...
- Beta 2 subunit propeptides influence cooperative proteasome assembly.
- Juvenile spondyloarthropathies and related arthritis.
- HLA-B27 and pathogenesis of spondyloarthropathies.
- HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum.
- HLA-B27 and Human β2-Microglobulin Affect the Gut Microbiota of Transgenic Rats.
- Summary of the 2005 annual research and education meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN).
- Polymorphism in the MHC-encoded LMP7 gene: association with JRA without functional significance for immunoproteasome assembly.
- Predisposing factors in the spondyloarthropathies: new insights into the role of HLA-B27.
- Evolution and transmission of stable CTL escape mutations in HIV infection.
- Development of spontaneous arthritis in beta2-microglobulin-deficient mice without expression of HLA-B27: association with deficiency of endogenous major histocompatib...
- Novel HY peptide antigens presented by HLA-B27.
- Identification of proteassemblin, a mammalian homologue of the yeast protein, Ump1p, that is required for normal proteasome assembly.
- HLA-B27 misfolding: a solution to the spondyloarthropathy conundrum?
- Novel propeptide function in 20 S proteasome assembly influences beta subunit composition.
- HLA-B27 misfolding and spondyloarthropathies: not so groovy after all?
- Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies.
- HLA-B27 subtype polymorphism and CTL epitope choice: studies with EBV peptides link immunogenicity with stability of the B27:peptide complex.
- Genetic diseases with rheumatic manifestations in children.
- Distinct recognition of closely-related HIV-1 and HIV-2 cytotoxic T-cell epitopes presented by HLA-B*2703 and B*2705.
- Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits.
- Naturally occurring A pocket polymorphism in HLA-B*2703 increases the dependence on an accessory anchor residue at P1 for optimal binding of nonamer peptides.
- Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS.
- Polymorphism in the LMP2 gene influences disease susceptibility and severity in HLA-B27 associated juvenile rheumatoid arthritis.
- Vasoactive intestinal peptide stimulates neuropeptide Y gene expression and causes neurite extension in PC12 cells through independent mechanisms.
- Differences in peptide presentation between B27 subtypes: the importance of the P1 side chain in maintaining high affinity peptide binding to B*2703.
- Allele-specific B pocket transplant in class I major histocompatibility complex protein changes requirement for anchor residue at P2 of peptide.
- Very-high-resolution two-dimensional electrophoretic separation of proteins on giant gels.
- Changes in the expression of hepatocyte protein gene-products associated with adaptation of cells to primary culture.
- The hepatic glucocorticoid domain: evidence for early and late hormone-mediated changes in the synthesis of individual protein gene products.
- Early heat shock proteins in primary thymocytes. Evidence for transcriptional and translational regulation.
- Glucocorticoid-induced messenger ribonucleic acids in rat thymic lymphocytes: rapid primary effects specific for glucocorticoids.
- Alpha subunit of eukaryotic translational initiation factor-2 is a heat-shock protein.
- Glucocorticoid-mediated induction of glucocortin: a rapid primary response common to major target tissues.
- Detection of mRNAs coding for translationally regulated heat-shock proteins in non-heat-shocked thymic lymphocytes.
- Electrophoretic separation of in vitro translation products on giant two-dimensional gels allows detailed analysis of cellular mRNAs.
- Lupus nephritis study--questions.
- Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis.
- The immunobiology of HLA-B27: variations on a theme.
- Pathogenesis of ankylosing spondylitis: current concepts.
- 2007 annual research and education meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN).
- Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-beta induction via X-box binding protein 1.
- Entheses and bones in spondyloarthritis: 2008 Annual Research and Education Meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN).
- Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis.
- From HLA-B27 to spondyloarthritis: a journey through the ER.
- An overview of genetics of paediatric rheumatic diseases.
- Current controversies in spondyloarthritis: SPARTAN.
- Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study.
Schools
University Of Rochester
Strong Meml Hospital University Rochester
Doctors Specialties
- Pediatric Rheumatology
Accepted Insurances
Education
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Duke University Hospital -
University of Rochester -
University of Rochester School of Medicine and Dentistry
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