Associate Professor, Pediatrics, University of Cincinnati College of Medicine
Pediatric Rheumatology
Dr. Alexei A. Grom, MD
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Alexei Grom practices Pediatric Rheumatology. He received awards:"Fellow". Alexei Grom is a published MD. He published 61 publications, including: 'Contrasting cytokine profiles in the synovium of different forms of juvenile rheumatoid arthritis and juvenile spondyloarthropathy: prominence of interleukin 4 in rest...'
Publications
- 2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American Coll...
- A Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis.
- Whole-exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic Arthritis and familial hemophagocytic lymphohistiocytosis.
- Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine-Directed Therapies.
- Canakinumab for the treatment of systemic juvenile idiopathic Arthritis.
- Macrophage activation Syndrome and cytokine-directed therapies.
- Follistatin-like Protein 1 and the Ferritin/Erythrocyte Sedimentation Rate Ratio Are Potential Biomarkers for Dysregulated Gene Expression and Macrophage Activation Sy...
- Gene-expression signatures differ between different clinical forms of Familial hemophagocytic lymphohistiocytosis.
- The limited role of interferon-γ in systemic juvenile idiopathic Arthritis cannot be explained by cellular hyporesponsiveness.
- Update on the pathogenesis and treatment of systemic idiopathic Arthritis.
- Pathogenesis of systemic juvenile idiopathic Arthritis: some answers, more questions.
- Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis.
- Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic Arthritis.
- Gene Expression Profiles from Peripheral Blood Mononuclear Cells Are Sensitive to Short Processing Delays.
- Heterogeneity in juvenile idiopathic Arthritis: impact of molecular profiling based on DNA polymorphism and gene expression patterns.
- Macrophage activation Syndrome: advances towards understanding pathogenesis.
- Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic Arthritis.
- Gene expression signatures in polyarticular juvenile idiopathic Arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
- Macrophage activation syndrome in patients with systemic juvenile idiopathic Arthritis is associated with MUNC13-4 polymorphisms.
- Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic Arthritis reveals molecular heterogeneity that may pr...
- B cell depletion: on the rise.
- The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic Juvenile...
- Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with Juvenile dermatomyosit...
- Feasibility and construct validity of the parent willingness-to-pay technique for children with juvenile idiopathic Arthritis.
- Natural killer cell dysfunction: A common pathway in systemic-onset juvenile rheumatoid Arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis?
- Macrophage activation Syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?
- Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid Arthritis and macrophage activation syndrome.
- Interleukin-15 inhibits sodium nitroprusside-induced apoptosis of synovial fibroblasts and vascular endothelial cells.
- Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic Arthritis: implications for pathogenesis.
- Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid Arthritis synovial tissue.
- Systemic JIA: new developments in the understanding of the pathophysiology and therapy.
- Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid Arthritis and macrophage activation syndrome.
- Urinary neutrophil gelatinase-associated lipocalin as a biomarker of nephritis in childhood-onset systemic Lupus erythematosus.
- Macrophage activation syndrome in Juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients.
- Histiocytic disorders: recent insights into pathophysiology and practical guidelines.
- Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic Arthritis.
- Expression of angiogenic factors in juvenile rheumatoid Arthritis: correlation with revascularization of human synovium engrafted into SCID mice.
- Etanercept in the treatment of macrophage activation Syndrome.
- Immunohistological characteristics of T cell infiltrates in different forms of childhood onset chronic Arthritis.
- Antibodies to the 45 kDa DEK nuclear antigen in pauciarticular onset juvenile rheumatoid Arthritis and iridocyclitis: selective association with MHC gene.
- Comparative sequence analysis of the human T cell receptor beta chain in juvenile rheumatoid Arthritis and juvenile spondylarthropathies: evidence for antigenic select...
- Contrasting cytokine profiles in the synovium of different forms of juvenile rheumatoid Arthritis and juvenile spondyloarthropathy: prominence of interleukin 4 in rest...
- Patterns of expression of tumor necrosis factor alpha, tumor necrosis factor beta, and their receptors in synovia of patients with juvenile rheumatoid Arthritis and ju...
- Juvenile rheumatoid Arthritis and the trimolecular complex (HLA, T cell receptor, and antigen). Differences from rheumatoid Arthritis.
- Patterns of T lymphocyte clonal expansion in HLA-typed patients with juvenile rheumatoid Arthritis.
- Angiopoietin-like-4 is a potential angiogenic mediator in Arthritis.
- Dominant T-cell-receptor beta chain variable region V beta 14+ clones in juvenile rheumatoid Arthritis.
- Macrophage activation syndrome in systemic juvenile rheumatoid Arthritis.
- Systemic features and early prognostic factors in Hispanic and non-Hispanic children from the United States of America and Mexico with systemic Juvenile idiopathic art...
- T-cell receptor BV6S1 null alleles and HLA-DR1 haplotypes in polyarticular outcome juvenile rheumatoid Arthritis.
- Gene expression in juvenile Arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of Arthritis.
- Reduced expression of a human V beta 6.1 T-cell receptor allele.
- On the mechanism of protection of distal joints after local gene transfer in collagen-induced Arthritis.
- Does systemic-onset juvenile idiopathic Arthritis belong under juvenile idiopathic Arthritis?
- T-cell and T-cell receptor abnormalities in the immunopathogenesis of juvenile rheumatoid Arthritis.
- [Clinico-immunologic heterogeneity of chronic Arthritis in children].
- Vitamin D status is a determinant of atorvastatin effect on carotid intima medial thickening progression rate in children with Lupus: an Atherosclerosis Prevention in ...
- Vitamin D deficiency is common and associated with increased C-reactive protein in children and young adults with Lupus: an Atherosclerosis Prevention in Pediatric Lup...
- Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic Arthritis.
- Monocyte microRNA expression in active systemic juvenile idiopathic Arthritis implicates miR-125a-5p in polarized monocyte phenotypes.
Conditions Treated
- Amyloidosis
- Arthritis
- Dermatomyositis
- Familial Mediterranean Fever
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Doctors Specialties
- Pediatric Rheumatology
Accepted Insurances
Awards
- Fellow
Education
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Cincinnati Children's Hospital Medical Center -
St Petersburg Medical State Academy
Hospital
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Cincinnati Children's Hospital Medical Center
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