Clinical Director, Endocrine Division, Massachusetts General Hospital, Associate Professor of Medicine, Harvard Medical School
Endocrinology
Dr. Frances J. Hayes, MD
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Dr. Frances J. Hayes works in the field of Endocrinology. Frances Hayes has written publications. He has 66 publications published with PubMed. The lastest paper is: 'Hypogonadotropic hypogonadism.' He is registered with Medicare and accepts Medicare payments.
Publications
- Testosterone, free testosterone, and free androgen index in women: Reference intervals, biological variation, and diagnostic value in polycystic ovary syndrome.
- Turner syndrome: update on biology and management across the life span.
- Widespread use of performance-enhancing drugs-an inconvenient truth.
- Trial of Recombinant Follicle Stimulating Hormone (rFSH) Pre-treatment for GnRH-induced Fertility in Patients with Congenital Hypogonadotropic Hypogonadism.
- Reversal and Relapse of Hypogonadotropic Hypogonadism: Resilience and Fragility of the Reproductive Neuroendocrine System.
- Abrupt Decrease in Serum Testosterone Levels After an Oral Glucose Load in Men: Implications for Screening for Hypogonadism.
- The long-term clinical follow-up and natural history of men with adult-onset idiopathic hypogonadotropic hypogonadism.
- Congenital idiopathic hypogonadotropic hypogonadism: evidence of defects in the hypothalamus, pituitary, and testes.
- Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism.
- Mutations in prokineticin 2 and prokineticin receptor 2 genes in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum.
- Inverse association of testosterone and the metabolic syndrome in men is consistent across race and ethnic groups.
- Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine.
- The relative role of gonadal sex steroids and gonadotropin-releasing hormone pulse frequency in the regulation of follicle-stimulating hormone secretion in men.
- Relative roles of inhibin B and sex steroids in the negative feedback regulation of follicle-stimulating hormone in men across the full spectrum of seminiferous epithe...
- Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem ...
- Menstrual cycle dysfunction associated with neurologic and psychiatric disorders: their treatment in adolescents.
- Acute sex steroid withdrawal reduces insulin sensitivity in healthy men with idiopathic hypogonadotropic hypogonadism.
- Reversal of idiopathic hypogonadotropic hypogonadism.
- Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism.
- Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline.
- Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism.
- Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men.
- Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men.
- Reversible kallmann syndrome, delayed puberty, and isolated anosmia occurring in a single family with a mutation in the fibroblast growth factor receptor 1 gene.
- High-resolution reference ranges for estradiol, luteinizing hormone, and follicle-stimulating hormone in men and women using the AxSYM assay system.
- Comparison of inhibin A immunoassays: recommendation for adoption of standardized reporting.
- Acute stress masking the biochemical phenotype of partial androgen insensitivity syndrome in a patient with a novel mutation in the androgen receptor.
- Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism.
- The role of prior pubertal development, biochemical markers of testicular maturation, and genetics in elucidating the phenotypic heterogeneity of idiopathic hypogonado...
- Coding sequence analysis of GNRHR and GPR54 in patients with congenital and adult-onset forms of hypogonadotropic hypogonadism.
- Impact of acute biochemical castration on insulin sensitivity in healthy adult men.
- Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.
- Mass spectrometric and physiological validation of a sensitive, automated, direct immunoassay for serum estradiol using the Architect.
- Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation.
- Cancer: Risk of hypogonadism in male survivors of childhood cancer.
- Androgens and the ageing male and female.
- Importance of inhibin B in the regulation of FSH secretion in the human male.
- Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback.
- Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating horm...
- The importance of autosomal genes in Kallmann syndrome: genotype-phenotype correlations and neuroendocrine characteristics.
- Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism.
- Clinical review 96: Differential control of gonadotropin secretion in the human: endocrine role of inhibin.
- Use of a gonadotropin-releasing hormone antagonist as a physiologic probe in polycystic ovary syndrome: assessment of neuroendocrine and androgen dynamics.
- Free alpha-subunit is superior to luteinizing hormone as a marker of gonadotropin-releasing hormone despite desensitization at fast pulse frequencies.
- Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations.
- The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormon...
- Genetics of hypogonadotropic hypogonadism.
- Insights into hypothalamic-pituitary dysfunction in polycystic ovary syndrome.
- Hypogonadotropic hypogonadism.
- Testis morphology in patients with idiopathic hypogonadotropic hypogonadism.
- Gonadotropin pulsations across development.
- Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes.
- Testosterone--fountain of youth or drug of abuse?
- Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis.
- Activity of the renin-angiotensin-aldosterone axis is dependent on the occurrence of edema in growth hormone (GH)-deficient adults treated with GH.
- Gender difference in the response of growth hormone (GH)-deficient adults to GH therapy.
- The P1 ParA protein and its ATPase activity play a direct role in the segregation of plasmid copies to daughter cells.
- Aggressive thyroid cancer associated with toxic nodular goitre.
- The occurrence of lymphocytic hypophysitis in a first but not subsequent pregnancy.
- Virilization in a postmenopausal woman as a result of hilus cell hyperplasia associated with a simple ovarian cyst.
- Rapid liquid chromatographic-mass spectrometric assay for oxymetazoline in whole rat blood.
- Structure-function correlations in the XerD site-specific recombinase revealed by pentapeptide scanning mutagenesis.
- A newly identified, essential catalytic residue in a critical secondary structure element in the integrase family of site-specific recombinases is conserved in a simil...
- A family of stability determinants in pathogenic bacteria.
- Functional assay for BRCA1: mutagenesis of the COOH-terminal region reveals critical residues for transcription activation.
Conditions Treated
- Adrenal Insufficiency
- Hyperparathyroidism
- Osteopenia
Doctors Specialties
- Reproductive Endocrinology
- Endocrinology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- BlueConnect HMO
- Blue with Managed Care Behavioral Health HMO
- Preferred Blue PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- GHI PPO
- Choice Care PPO
- MultiPlan PPO
- PHCS Network PPO
- Tufts PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Education
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University College of Dublin National Univ SOM
Hospital
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Massachusetts General Hospital
Drug Facts
| NPI NUMBER | 1528058856 | |
| NPPES Provider LastName | HAYES | |
| NPPES Provider FirstName | FRANCES | |
| NPPES Provider ZIPCode | 021142621 | |
| NPPES Provider State | MA | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 93.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1528058856 |
| Last Name Of The Provider | HAYES |
| First Name Of The Provider | FRANCES |
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