Division Chief for Nephrology Professor of Medicine University of Louisville School of Medicine
Nephrology
Dr. Eleanor Lederer, MD
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Eleanor Lederer works in the field of Nephrology. She went to medical school at Baylor College of Medicine. She has 2 awards "Regional Top Doctor" and "Fellow (ASNF)". Eleanor Lederer is also published. She has 58 publications published. The lastest publication: "Type II Na-Pi cotransport is regulated transcriptionally by ambient bicarbonate/carbon dioxide tension in OK cells.' Eleanor Lederer accepts Medicare payments and is registered with Medicare.gov.
Publications
- Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA.
- Renal phosphate transporters.
- Regulation of Serum Phosphate.
- Structural determinants for the ouabain-stimulated increase in Na-K ATPase activity.
- Angiotensin-II induced Hypertension and renovascular remodelling in tissue inhibitor of metalloproteinase 2 knockout mice.
- Aldosterone regulates Na(+), K(+) ATPase activity in human Renal proximal tubule cells through mineralocorticoid receptor.
- Vacuolar ATPase driven potassium transport in highly metastatic breast cancer cells.
- Parathyroid hormone (PTH) decreases sodium-phosphate cotransporter type IIa (NpT2a) mRNA stability.
- Clinical Consequences of Mutations in Sodium Phosphate Cotransporters.
- Inhibition of tRNA methylation in vitro and in whole cells by an oncostatic S-adenosyl-homocysteine (SAH) analogue: 5''-deoxy 5''-S-isobutyl adenosine (SIBA).
- Management of Acute hydronephrosis of pregnancy by ureteral stenting: risk of stone formation.
- TMB-8 prevents the hydroosmotic Response to ADH in rabbit cortical collecting tubules.
- Unusual glomerular lesion in a patient receiving long-term interferon alpha.
- Correlation between percutaneous renal biopsy and the indium-111-labeled platelet scan in diagnosing Acute renal allograft rejection.
- Patent foramen ovale presenting as refractory hypoxemia after Heart transplantation.
- Electrophoretic study of tartrate-resistant acid phosphatase isoforms in EndStage renal disease and rheumatoid arthritis.
- Pulmonary embolism due to catheter fracture from a tunneled dialysis catheter.
- Acid-induced stimulation of Na-Pi cotransport in OK cells: molecular characterization and effect of dexamethasone.
- Tartrate-resistant acid phosphatase isoform 5a as an inflammation marker in end-stage Renal disease.
- Development, implementation, and results of the ASN in-training examination for fellows.
- Pancreas transplants for Diabetic nephropathy: a time for reassessment.
- The flux of phosphate: rapid evolution.
- Cellular mechanisms involved in the Acute adaptation of OK cell Na/Pi-cotransport to high- or low-Pi medium.
- Under-recognition of chronic Kidney disease in elderly outpatients.
- Role of carboxylmethylation in chemoattractant receptor-stimulated G protein activation and functional Responses.
- Azotemia, TNF alpha, and LPS prime the human neutrophil oxidative burst by distinct mechanisms.
- Role of isoprenoid Metabolism in chemotactic peptide receptor-mediated G protein activation.
- Type II Na-Pi cotransport is regulated transcriptionally by ambient bicarbonate/carbon dioxide tension in OK cells.
- IGF-I and vanadate stimulate Na/Pi-cotransport in OK cells by increasing type II Na/Pi-cotransporter protein stability.
- Parathyroid hormone leads to the lysosomal degradation of the Renal type II Na/Pi cotransporter.
- Regulation of the Renal type IIa Na/Pi cotransporter by cGMP.
- Evidence for a PTH-independent humoral mechanism in post-transplant hypophosphatemia and phosphaturia.
- Effect of prenylcysteine analogues on chemoattractant receptor-mediated G protein activation.
- Desensitization by protein kinase C activation differentially uncouples formyl peptide receptors from effector enzymes in HL-60 granulocytes.
- PDZ-domain interactions and apical expression of type IIa Na/P(i) cotransporters.
- Regulation of expression of type II sodium-phosphate cotransporters by protein kinases A and C.
- Parathyroid hormone-dependent degradation of type II Na+/Pi cotransporters.
- Parathyroid hormone regulation of NA+,K+-ATPase requires the PDZ 1 domain of sodium hydrogen exchanger regulatory factor-1 in opossum Kidney cells.
- Acute and chronic changes in cholesterol modulate Na-Pi cotransport activity in OK cells.
- P2 purinoceptor stimulation attenuates PTH inhibition of phosphate uptake by a G protein-dependent mechanism.
- Dopamine regulates phosphate uptake by opossum Kidney cells through multiple counter-regulatory receptors.
- PTH and DA regulate Na-K ATPase through divergent pathways.
- Parathyroid hormone stimulates extracellular signal-regulated kinase (ERK) activity through two independent signal transduction pathways: role of ERK in sodium-phospha...
- Role of vacuolar ATPase in the trafficking of Renal type IIa sodium-phosphate cotransporter.
- Dopamine regulation of Na+-K+-ATPase requires the PDZ-2 domain of sodium hydrogen regulatory factor-1 (NHERF-1) in opossum Kidney cells.
- Cystathionine ?-synthase and cystathionine ?-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation.
- Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human Kidney proximal tubule cells.
- Steroidogenic Acute regulatory-related lipid transfer domain protein 5 localization and regulation in renal tubules.
- Development of clinical practice guidelines: are we defining the issues too narrowly?
- Proteomic analysis of renal calculi indicates an important role for inflammatory processes in Calcium stone formation.
- PTH-mediated regulation of Na+-K+-ATPase requires Src kinase-dependent ERK phosphorylation.
- Novel regulatory function for NHERF-1 in Npt2a transcription.
- Parathyroid hormone-mediated regulation of Na+-K+-ATPase requires ERK-dependent translocation of protein kinase Calpha.
- Clathrin-mediated endocytosis of Na+,K+-ATPase in Response to parathyroid hormone requires ERK-dependent phosphorylation of Ser-11 within the alpha1-subunit.
- Parathyroid hormone regulation of type II sodium-phosphate cotransporters is dependent on an A kinase anchoring protein.
- Na+/H+ exchanger-regulatory factor 1 mediates inhibition of phosphate transport by parathyroid hormone and second messengers by acting at multiple sites in opossum kid...
- Role of NHERF-1 in regulation of the activity of Na-K ATPase and sodium-phosphate co-transport in epithelial cells.
Schools
Baylor College Of Medicine
Bcm Affiliated Hospitals
Ben Taub General Hospital
Procedures Preformed
- Hemodialysis
- Peritoneal Dialysis
Conditions Treated
- Acidosis
- Acute Kidney Failure
- Calcium Metabolism Disorders
- Chronic Kidney Diseases
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Doctors Specialties
- Nephrology
Accepted Insurances
Awards
- Regional Top Doctor
- Fellow (ASNF)
Education
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Baylor College of Medicine
Hospital
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Jewish Hospital -
Norton Hospital -
University of Louisville Hospital
Drug Facts
| NPI NUMBER | 1952380917 | |
| NPPES Provider LastName | LEDERER | |
| NPPES Provider FirstName | ELEANOR | |
| NPPES Provider ZIPCode | 402021715 | |
| NPPES Provider State | KY | |
| Specialty Description | Nephrology | |
| Total Claim Count | 653.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1952380917 |
| Last Name Of The Provider | LEDERER |
| First Name Of The Provider | ELEANOR |
| View All |
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