Pediatric Hematologist/Oncologist Children's Hospitals of Minnesota

Pediatric Hematology & Oncology

Yoav Messinger practices Pediatric Hematology & Oncology. Yoav Messinger is a published MD as well. He has 42 publications published. The latest was: Treatment of human B-cell precursor leukemia in SCID mice using a combination of the investigational biotherapeutic agent B43-PAP with cytosine arabinoside.

Publications

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• The genomic landscape of juvenile myelomonocytic leukemia.
• Can congenital pulmonary airway malformation be distinguished from Type I pleuropulmonary blastoma based on clinical and radiological features?
• Radiographic Screening of Infants and Young Children With Genetic Predisposition for Rare Malignancies: DICER1 Mutations and Pleuropulmonary Blastoma.
• The effects of Dexamethasone on sleep in young children with Acute Lymphoblastic Leukemia.
• Nasal chondromesenchymal hamartomas arise Secondary to germline and somatic mutations of DICER1 in the pleuropulmonary blastoma tumor predisposition disorder.
• Pleuropulmonary blastoma: A report on 350 central pathology-confirmed pleuropulmonary blastoma cases by the International Pleuropulmonary Blastoma Registry.
• Reply: Serum microRNA screening for DICER1-associated pleuropulmonary blastoma.
• Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop seq...
• Judicious DICER1 testing and surveillance imaging facilitates early diagnosis and cure of pleuropulmonary blastoma.
• DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma.
• Safety and Efficacy of Metformin for Therapy-induced Hyperglycemia in Children With Acute Lymphoblastic Leukemia.
• Ofatumumab for refractory opsoclonus-myoclonus syndrome following treatment of neuroblastoma.
• Bortezomib with chemotherapy is highly active in advanced B-precursor acute lymphoblastic leukemia: Therapeutic Advances in Childhood Leukemia Lymphoma (TACL) Study.
• Elimination of antibodies to recombinant enzyme in Pompe's Disease.
• Temporal order of RNase IIIb and loss-of-function mutations during development determines phenotype in DICER1 syndrome: a unique variant of the two-hit tumor suppressi...
• DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
• Treatment of therapy-refractory B-lineage acute lymphoblastic leukemia with an apoptosis-inducing CD19-directed tyrosine kinase inhibitor.
• Clinical pharmacokinetics of the CD19 receptor-directed tyrosine kinase inhibitor B43-Genistein in patients with B-lineage lymphoid Malignancies.
• Toxicity, biological activity, and pharmacokinetics of TXU (anti-CD7)-pokeweed antiviral protein in chimpanzees and adult patients infected with human immunodeficiency...
• A critical risk-benefit assessment argues against the use of anthracyclines in induction regimens for newly diagnosed childhood acute lymphoblastic leukemia.
• Evaluation of temozolomide in a SCID mouse model of human B-Cell precursor leukemia.
• Treatment of human B-Cell precursor leukemia in SCID mice using a combination of the investigational biotherapeutic agent B43-PAP with cytosine arabinoside.
• In vivo toxicity, pharmacokinetics, and antileukemic activity of TXU (anti-CD7)-pokeweed antiviral protein immunotoxin.
• Pharmacokinetic features, immunogenicity, and toxicity of B43(anti-CD19)-pokeweed antiviral protein immunotoxin in cynomolgus monkeys.
• In vivo biotherapy of HL-60 myeloid leukemia with a genetically engineered recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulatin...
• In vivo toxicity, pharmacokinetics, and anticancer activity of Genistein linked to recombinant human epidermal growth factor.
• In vivo toxicity and pharmacokinetic features of B43 (anti-CD19)-genistein immunoconjugate in nonhuman primates.
• Selective homing of human leukemic B-Cell precursors to specific lymphohematopoietic microenvironments in SCID mice: a role for the beta 1 integrin family surface adhe...
• Signal transduction through the beta1 integrin family surface adhesion molecules VLA-4 and VLA-5 of human B-Cell precursors activates CD19 receptor-associated protein-...
• Autoimmune Diseases other than lupus share common anti-DNA idiotypes.
• Novel DNA sequences at chromosome 10q26 are amplified in human gastric carcinoma Cell lines: molecular cloning by competitive DNA reassociation.
• Successful plasmapheresis for extreme hyperbilirubinemia caused by acute Epstein-Barr virus.
• Familial association of pleuropulmonary blastoma with cystic nephroma and other renal tumors: a report from the International Pleuropulmonary Blastoma Registry.
• Renal outcome of neonatal renal venous thrombosis: review of 28 patients and effectiveness of fibrinolytics and heparin in 10 patients.
• Type I pleuropulmonary blastoma: a report from the International Pleuropulmonary Blastoma Registry.
• Pediatric ovarian tumors: a review of 67 cases.
• Ovarian sex cord-stromal tumors, pleuropulmonary blastoma and DICER1 mutations: a report from the International Pleuropulmonary Blastoma Registry.
• Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances i...
• Pseudometastasis Secondary to histoplasmosis infection: false-positive PET/CT findings.
• DICER1 mutations in familial pleuropulmonary blastoma.
• Successful immune tolerance induction to enzyme replacement therapy in CRIM-negative infantile Pompe Disease.

Schools

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• Sackler School Of Medicine Tel Aviv University

• Beilinson Med Center

• Golda Hasharon Med Center

• University Of Minnesota

Conditions Treated

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• Anemia
• Hodgkin's Disease
• Lymphoma
• Lymphoma, Large Cell, Anaplastic
• View All

Doctors Specialties

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• Pediatric Hematology
• Oncology

Accepted Insurances

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Education

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• University of Minnesota
• University of Minnesota at Fairview
• Tel Aviv University Sackler

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