Assistant Professor, Psychiatry, University of Pittsburgh School of Medicine
Psychiatry
Dr. William G. Frankle, MD
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William Frankle works in the field of Psychiatry. He attended New York Medical College. Dr. William G. Frankle has written publications. He has 42 publications published with PubMed. The lastest publication is: 'Imaging dopamine transmission in the frontal cortex: a simultaneous microdialysis and [(11)C]FLB 457 PET study.' William G. Frankle is registered with Medicare.
Publications
- Imaging dopamine transmission in the frontal cortex: a simultaneous microdialysis and [(11)C]FLB 457 PET study.
- Improved working memory but no effect on striatal vesicular monoamine transporter type 2 after omega-3 polyunsaturated Fatty Acid supplementation.
- [11C]NNC 112 selectivity for dopamine D1 and serotonin 5-HT(2A) receptors: a PET study in healthy human subjects.
- Prefrontal cortical projections to the midbrain in primates: evidence for a sparse connection.
- Clozapine-associated reduction in arrest rates of psychotic patients with criminal histories.
- Bipolar depression: relationship between episode length and antidepressant treatment.
- Occupancy of dopamine D2 receptors by the atypical antipsychotic Drugs risperidone and olanzapine: theoretical implications.
- Comparative evaluation of serotonin transporter radioligands 11C-DASB and 11C-McN 5652 in healthy humans.
- Positron emission tomography and single photon emission CT molecular imaging in schizophrenia.
- Cocaine Dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior.
- Presence of irritability during depressive episodes in bipolar Disorder.
- Clinical characteristics, cognitive functioning, and criminal histories of outpatients with schizophrenia.
- The synaptic hypothesis of schizophrenia.
- Neuroreceptor imaging in psychiatric Disorders.
- Altered prefrontal dopaminergic function in chronic recreational ketamine users.
- Neuroreceptor imaging in psychiatry: theory and applications.
- Mechanism of action of antipsychotic Drugs: from dopamine D(2) receptor antagonism to glutamate NMDA facilitation.
- Serotonin transporter availability in patients with schizophrenia: a positron emission tomography imaging study with [11C]DASB.
- Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652.
- Effects of reduced endogenous 5-HT on the in vivo binding of the serotonin transporter radioligand 11C-DASB in healthy humans.
- Serotonin 1A receptor availability in patients with schizophrenia and schizo-affective Disorder: a positron emission tomography imaging study with [11C]WAY 100635.
- Estimation of serotonin transporter parameters with 11C-DASB in healthy humans: reproducibility and comparison of methods.
- In vivo evidence for low striatal vesicular monoamine transporter 2 (VMAT2) availability in Cocaine abusers.
- The 5-HT(2A) receptor and serotonin transporter in Asperger's Disorder: A PET study with [¹¹C]MDL 100907 and [¹¹C]DASB.
- Imaging of dopamine D(2/3) agonist binding in cocaine Dependence: a [(11) C]NPA positron emission tomography study.
- Amphetamine induced dopamine release increases anxiety in individuals recovered from anorexia nervosa.
- Evaluation of dopamine D₂/₃ specific binding in the cerebellum for the positron emission tomography radiotracer [¹¹C]FLB 457: implications for measuring cortical dopam...
- Measurement of the serotonin 1A receptor availability in patients with schizophrenia during treatment with the antipsychotic medication ziprasidone.
- No effect of dopamine depletion on the binding of the high-affinity D 2/3 radiotracer [11C]FLB 457 in the human cortex.
- Positron emission tomography imaging of dopamine D₂/₃ receptors in the human cortex with [¹¹C]FLB 457: reproducibility studies.
- Increased serotonin 2A receptor availability in the orbitofrontal cortex of physically aggressive personality Disordered patients.
- Increased synaptic dopamine function in associative regions of the striatum in schizophrenia.
- A comparative evaluation of the dopamine D(2/3) agonist radiotracer [11C](-)-N-propyl-norapomorphine and antagonist [11C]raclopride to measure Amphetamine-induced dopa...
- Human biodistribution and dosimetry of the D2/3 agonist 11C-N-propylnorapomorphine (11C-NPA) determined from PET.
- Positron emission tomography imaging of D(2/3) agonist binding in healthy human subjects with the radiotracer [(11)C]-N-propyl-norapomorphine: preliminary evaluation a...
- Positron emission tomography imaging of Amphetamine-induced dopamine release in the human cortex: a comparative evaluation of the high affinity dopamine D2/3 radiotrac...
- Positron emission tomography imaging of the serotonin transporter and 5-HT(1A) receptor in Alcohol dependence.
- Tiagabine increases [11C]flumazenil binding in cortical brain regions in healthy control subjects.
- Dose-occupancy study of striatal and extrastriatal dopamine D2 receptors by aripiprazole in schizophrenia with PET and [18F]fallypride.
- COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET.
- Neuroreceptor imaging studies in schizophrenia.
Schools
New York Medical College
Conditions Treated
- Adjustment Disorder
- Alcohol-Induced Mental Disorders
- Alcoholism (Alcohol Dependence)
- Amphetamine and Other Psychostimulant Dependence
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Doctors Specialties
- Psychiatry
Accepted Insurances
Education
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Massachusetts General Hospital -
New York Presbyterian Hospital - Cornell Campus -
New York Medical College
Drug Facts
| NPI NUMBER | 1467474023 | |
| NPPES Provider LastName | FRANKLE | |
| NPPES Provider FirstName | WILLIAM | |
| NPPES Provider ZIPCode | 152132593 | |
| NPPES Provider State | PA | |
| Specialty Description | Psychiatry | |
| Total Claim Count | 135.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1467474023 |
| Last Name Of The Provider | FRANKLE |
| First Name Of The Provider | WILLIAM |
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