Professor, Pediatrics, University of Cincinnati College of Medicine
Pediatric Pulmonology
Dr. William D. Hardie, MD
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William Hardie works in the field of Pediatric Pulmonology. He went to Vanderbilt University School of Medicine. He has 2 awards "Regional Top Doctor" and "Whos Who in Medicine and Healthcare". William Hardie is also a published MD. He has 48 paper published. The most recent paper is: Complicated parapneumonic effusions in children caused by penicillin-nonsusceptible Streptococcus pneumoniae.
Publications
- Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary Fibrosis.
- Bone-Marrow-Derived Stromal Cells are Invasive and Hyperproliferative and alter TGFα-Induced Pulmonary Fibrosis.
- Targeted overexpression of TGF-? in the corneal epithelium of adult transgenic mice induces changes in anterior segment morphology and activates Non-canonical Wnt sign...
- MEK-ERK pathway modulation ameliorates pulmonary Fibrosis associated with epidermal growth factor receptor activation.
- Rapamycin Decreases Airway Remodeling and Hyperreactivity in a Transgenic Model of Noninflammatory Lung Disease.
- Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma.
- Signaling pathways in the epithelial origins of pulmonary Fibrosis.
- Pathogenesis of Interstitial Lung Disease in Children and Adults.
- Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary Fibrosis.
- Rapamycin prevents transforming growth factor-alpha-induced pulmonary Fibrosis.
- Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.
- Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice.
- Surfactant-associated protein B is critical to survival in nickel-induced injury in mice.
- Emerging concepts in the pathogenesis of lung Fibrosis.
- 50 Years Ago in The Journal of Pediatrics Pediatric Empyema: A Second Look at its Incidence and Importance. Kiesewetter, WB, Rusnock JR, Girdany BR. J Pediatr 1959;54:...
- Acceptability and repeatability of spirometry in children using updated ATS/ERS criteria.
- EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary Fibrosis.
- Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.
- Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary Fibrosis.
- Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis.
- TGF-alpha perturbs surfactant homeostasis in vivo.
- Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary Fibrosis.
- Disrupted Pulmonary vascular development and Pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha.
- Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha.
- Acute lung injury: functional genomics and genetic susceptibility.
- Dual Targeting of MEK and PI3K Pathways Attenuates Established and Progressive Pulmonary Fibrosis.
- Functional genomics of oxidant-induced lung injury.
- Pneumococcal pleural empyemas in children.
- The role of cyclooxygenase products in lung injury induced by tumor necrosis factor in sheep.
- Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice.
- Cavitary lung lesions in a 2-year-old child.
- Pathogenomic mechanisms for particulate matter induction of acute lung injury and inflammation in mice.
- Dose-dependent lung remodeling in transgenic mice expressing transforming growth factor-alpha.
- Declining pediatric subspecialty training and rising educational debt.
- Measuring pleural fluid pH: high correlation of a handheld unit to a traditional tabletop blood gas analyzer.
- Attenuation of acute lung injury in transgenic mice expressing human transforming growth factor-alpha.
- Immunolocalization of transforming growth factor alpha and epidermal growth factor receptor in lungs of patients with Cystic fibrosis.
- Complicated parapneumonic effusions in children caused by penicillin-nonsusceptible Streptococcus pneumoniae.
- Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha.
- Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor.
- Transient induction of TGF-alpha disrupts lung morphogenesis, causing Pulmonary disease in adulthood.
- Persistent abnormal lung function after childhood empyema.
- The effect of thromboxane A2 receptor antagonism on amphotericin B-induced renal vasoconstriction in the rat.
- Studies of an antiendotoxin antibody in preventing the physiologic changes of endotoxemia in awake sheep.
- Effects of intravenous amphotericin B infusion on hemodynamics and airway mechanics in awake sheep.
- Effect of cyclooxygenase inhibition on amphotericin B-induced lung injury in awake sheep.
- Pulmonary Morbidity in Infancy after Exposure to Chorioamnionitis in Late Preterm Infants.
Schools
Vanderbilt University School Of Medicine
Childrens Hospital Med Center
Conditions Treated
- Bronchiectasis
- Cystic Fibrosis
- Pneumonitis (Due to Solids or Liquids)
- Pulmonary Hypertension
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Doctors Specialties
- Pediatric Pulmonology
Accepted Insurances
Awards
- Regional Top Doctor
- Whos Who in Medicine and Healthcare
Education
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Cincinnati Children's Hospital Medical Center -
Vanderbilt University School of Medicine
Hospital
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Cincinnati Children's Hospital Medical Center
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