Associate Professor of Pediatrics, Massachusetts General Hospital
Allergy & Immunology
Dr. Wayne G. Shreffler, MD
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Doctor Wayne G. Shreffler, MD is an expert in the field of Allergy & Immunology. He attended Mount Sinai School of Medicine. He received awards:"Excellence in ServiceAward" and "AAAAI Travel Award". Wayne Shreffler is a published doctor and has 56 publications published. The lastest was: 'Genes controlling ion permeability in both motorneurons and muscle.'
Publications
- Mechanisms Underlying Induction of Tolerance to Foods.
- The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease.
- BATting above average: Basophil activation testing for peanut allergy.
- Tethered confocal endomicroscopy capsule for diagnosis and monitoring of eosinophilic esophagitis.
- Tolerance of baked milk in patients with cow's milk-mediated eosinophilic esophagitis.
- Identification of human CCR8 as a CCL18 receptor.
- Cow's Milk Allergy: A New Approach Needed?
- Basophil reactivity, wheal size, and immunoglobulin levels distinguish degrees of cow's milk tolerance.
- Development of a novel peptide microarray for large-scale epitope mapping of food allergens.
- Clinical efficacy and immune regulation with peanut oral immunotherapy.
- Epinephrine treatment is infrequent and biphasic reactions are rare in food-induced reactions during oral food challenges in children.
- Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergy.
- Clinical reactivity to raw peanut correlates with IgE binding to conformational epitopes of Ara h 1: a case report.
- Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy.
- Oral peanut immunotherapy in children with peanut anaphylaxis.
- Identification of IgE sequential epitopes of lentil (Len c 1) by means of peptide microarray immunoassay.
- Sublingual immunotherapy for peanut allergy: clinical and immunologic evidence of desensitization.
- Microarrayed recombinant allergens for diagnostic testing.
- Both the variability and level of mouse allergen exposure influence the phenotype of the immune response in workers at a mouse facility.
- Walnut Allergy in Peanut-Allergic Patients: Significance of Sequential Epitopes of Walnut Homologous to Linear Epitopes of Ara h 1, 2 and 3 in Relation to Clinical Rea...
- Food allergy and complementary feeding.
- Immunology in the Clinic Review Series; focus on allergies: basophils as biomarkers for assessing immune modulation.
- Determinants of food allergy.
- RE: Reply to Lifschitz.
- Longitudinal Perspective on Managing Refractory Eosinophilic Esophagitis.
- Identification and synthesis of a major conserved antigenic epitope of Trypanosoma cruzi.
- A rapid and simple diagnostic test for active visceral leishmaniasis.
- An improved serodiagnostic procedure for visceral leishmaniasis.
- The unc-8 and sup-40 genes regulate ion channel function in Caenorhabditis elegans motorneurons.
- Antibody responses of visceral leishmaniasis patients to gp63, a major surface glycoprotein of Leishmania species.
- Serodiagnosis of Chagas' disease by enzyme-linked immunosorbent assay using two synthetic peptides as antigens.
- Molecular characterization of a kinesin-related antigen of Leishmania chagasi that detects specific antibody in African and American visceral leishmaniasis.
- Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes.
- unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotion.
- Genes controlling ion permeability in both motorneurons and muscle.
- Microarray immunoassay: association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes.
- IgE and IgG4 epitope mapping by microarray immunoassay reveals the diversity of immune response to the peanut allergen, Ara h 2.
- Skin prick test to egg white provides additional diagnostic utility to serum egg white-specific IgE antibody concentration in children.
- Evaluation of basophil activation in food allergy: present and future applications.
- Lack of association of HLA class II alleles with peanut allergy.
- Transcytosis of IgE-antigen complexes by CD23a in human intestinal epithelial cells and its role in food allergy.
- The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro.
- Standardization and performance evaluation of mononuclear cell cytokine secretion assays in a multicenter study.
- Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy.
- Type 1 diabetes, autoimmune thyroid disease, and chronic urticaria.
- T(H)2 adjuvants: implications for food allergy.
- Tolerance to extensively heated milk in children with cow's milk allergy.
- Mapping of the IgE and IgG4 sequential epitopes of milk allergens with a peptide microarray-based immunoassay.
- Immunologic changes in children with egg allergy ingesting extensively heated egg.
- Basic science for the practicing physician: flow cytometry and cell sorting.
- Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein.
- The perfectly potent peanut.
- Allergen-specific basophil suppression associated with clinical tolerance in patients with milk allergy.
- Microarrayed allergen molecules for diagnostics of allergy.
- The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population.
Schools
New York University School Of Medicine
Albert Einstein College Med
Mt Sinai School Med
Doctors Specialties
- Pediatrics
- Allergy
- Immunology
Accepted Insurances
Awards
- Excellence in Service Award
- AAAAI Travel Award
Education
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Mount Sinai School of Medicine -
Albert Einstein College of Medicine -
NYU School of Medicine -
New York University -
University of Washington
Hospital
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Massachusetts General Hospital
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