Professor, Pathology, University of Utah School of Medicine
Pathology
Dr. Wade S. Samowitz, MD
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Wade Samowitz is an expert in the field of Pathology. He graduated from State University of New York Downstate Medical Center College of Medicine. He has 1 awards "Regional Top Doctor". Wade Samowitz has written publications. He has 101 publications published with PubMed. The lastest paper is: 'Gastrointestinal polyposis and nonpolyposis syndromes.'
Publications
- MicroRNA profiles in colorectal carcinomas, adenomas and normal colonic mucosa: variations in miRNA expression and disease progression.
- Sporadic microsatellite instability-high colon cancers rarely display immunohistochemical evidence of wnt signaling activation.
- An evaluation and replication of miRNAs with disease stage and colorectal cancer-specific mortality.
- Dance Well: Partnering With Reference Laboratories for Oncology Testing.
- ACMG technical standards and guidelines for genetic testing for inherited colorectal cancer (Lynch syndrome, familial adenomatous polyposis, and MYH-associated polypos...
- Template for Reporting Results of Biomarker Testing of Specimens From Patients With Carcinoma of the Colon and Rectum.
- BRAF V600E mutation detection by immunohistochemistry in colorectal carcinoma.
- Recurrent and founder mutations in the PMS2 gene.
- The frequency of previously undetectable deletions involving 3' Exons of the PMS2 gene.
- Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancer.
- A PIK3CA Pyrosequencing-Based Assay that Excludes Pseudogene Interference.
- Epidermal growth factor receptor pathway mutations and colorectal cancer therapy.
- Microsatellite instability and colorectal cancer.
- Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.
- Avoidance of pseudogene interference in the detection of 3' deletions in PMS2.
- Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
- Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.
- Lynch syndrome screening implementation: business analysis by a healthcare system.
- Clinical analysis of PMS2: mutation detection and avoidance of pseudogenes.
- Quantitative evaluation of CpG island methylation in hyperplastic polyps.
- Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer.
- MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer.
- Somatic alterations, metabolizing genes and smoking in rectal cancer.
- Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.
- The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer.
- Colonic adenoma risk in familial colorectal cancer--a study of six extended kindreds.
- DNA methylation in breast and colorectal cancers.
- Genetic and epigenetic changes in colon cancer.
- Confirmation of single exon deletions in MLH1 and MSH2 using quantitative polymerase chain reaction.
- PCR versus immunohistochemistry for microsatellite instability.
- The CpG island methylator phenotype in colorectal cancer.
- Thymidylate synthase polymorphisms and colon cancer: associations with tumor stage, tumor characteristics and survival.
- Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer.
- APC mutations and other genetic and epigenetic changes in colon cancer.
- Genetic admixture among Hispanics and candidate gene polymorphisms: potential for confounding in a breast cancer study?
- Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.
- Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality.
- An evidence-based, multidisciplinary approach to the clinical considerations, management, and surveillance of adrenal lesions in familial adenomatous polyposis: report...
- Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention.
- Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer.
- Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers.
- Interactions of peroxisome proliferator-activated receptor {gamma} and diet in etiology of colorectal cancer.
- p53 alterations in colon tumors: a comparison of SSCP/sequencing and immunohistochemistry.
- Genetic testing and phenotype in a large kindred with attenuated familial adenomatous polyposis.
- Hyperplastic-like colon polyps preceding microsatellite-unstable adenocarcinomas.
- Prognostic implications of BAX and TGFBRII mutations in colon cancers with microsatellite instability.
- Missense mismatch repair gene alterations, microsatellite instability, and hereditary nonpolyposis colorectal cancer.
- Prognostic significance of p53 mutations in colon cancer at the population level.
- CpG island methylation in colorectal cancer: past, present and future.
- Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and women.
- Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer.
- Microsatellite instability and survival in rectal cancer.
- Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.
- Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer.
- Frequency of familial colon cancer and hereditary nonpolyposis colorectal cancer (Lynch syndrome) in a large population database.
- Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet.
- PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).
- Aberrant methylation of the HRPT2 gene in parathyroid carcinoma.
- Tumor markers and rectal cancer: support for an inflammation-related pathway.
- CpG methylation analysis--current status of clinical assays and potential applications in molecular diagnostics: a report of the Association for Molecular Pathology.
- A comparison of colon and rectal somatic DNA alterations.
- Mismatch repair polymorphisms and risk of colon cancer, tumour microsatellite instability and interactions with lifestyle factors.
- Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes.
- Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors.
- Increased risk of colon cancer associated with a genetic polymorphism of SMAD7.
- Alcohol consumption and rectal tumor mutations and epigenetic changes.
- Associations between ERalpha, ERbeta, and AR genotypes and colon and rectal cancer.
- Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk.
- Phenotypic characteristics and risk of cancer development in hyperplastic polyposis: case series and literature review.
- Sex-specific differences in colon cancer associated with p53 mutations.
- Associations between BMI, energy intake, energy expenditure, VDR genotype and colon and rectal cancers (United States).
- Energy balance, insulin-related genes and risk of colon and rectal cancer.
- Associations between apoE genotype and colon and rectal cancer.
- PPARgamma, energy balance, and associations with colon and rectal cancer.
- Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway.
- Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer.
- Dietary calcium, vitamin D, VDR genotypes and colorectal cancer.
- Homogeneous amplification and mutation scanning of the p53 gene using fluorescent melting curves.
- GSTM-1 and NAT2 and genetic alterations in colon tumors.
- Diet activity, and lifestyle associations with p53 mutations in colon tumors.
- Estrogen and progesterone receptors in colon tumors.
- Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors.
- Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study.
- Associations between dietary intake and Ki-ras mutations in colon tumors: a population-based study.
- Estrogens reduce and withdrawal of estrogens increase risk of microsatellite instability-positive colon cancer.
- Regional reproducibility of microsatellite instability in sporadic colorectal cancer.
- Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer.
- Linear IgA bullous dermatosis responsive to a gluten-free diet.
- Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level.
- The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer.
- Uncommon TGFBRI allele is not associated with increased susceptibility to colon cancer.
- Associations between family history of colorectal cancer and genetic alterations in tumors.
- Hereditary aspects of colorectal adenomas.
- Population genetics of colonic cancer.
- Fluorescence localization of early colonic cancer in the rat by hematoporphyrin derivative.
- Microsatellite instability in human colonic cancer is not a useful clinical indicator of familial colorectal cancer.
- Genetic abnormalities in sporadic parathyroid adenomas: loss of heterozygosity for chromosome 3q markers flanking the calcium receptor locus.
- Alternatively spliced adenomatous polyposis coli (APC) gene transcripts that delete exons mutated in attenuated APC.
- Gastrointestinal polyposis and nonpolyposis syndromes.
- Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial.
Schools
SUNY Downstate Medical Center College Of Medicine
University Chicago HospClins
Johns Hopkins Hospital
Doctors Specialties
- Anatomic Pathology
- Pathology
Accepted Insurances
Awards
- Regional Top Doctor
Education
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Johns Hopkins University -
University of Chicago -
State University of New York Downstate Medical Center College of Medicine -
University of Texas Southwestern Medical School
Hospital
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University of Utah Health Care - Hospital and Clinics
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1912097536 |
| Last Name Of The Provider | SAMOWITZ |
| First Name Of The Provider | WADE |
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