Yale
Internal Medicine
Dr. Vlad G. Zaha, MD
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Vlad G. Zaha, MD is an expert in the field of Internal Medicine. He graduated from Indiana University School of Medicine. Indiana University School of Medicine is ranked 45/47 in Research/PrimaryCare. Dr. Vlad G. Zaha is a published physician as well. He has 15 publications published. The latest was: AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia.
Publications
- AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia.
- PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy.
- Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.
- Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.
- Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.
- A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.
- Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.
- Distinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulin.
- Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action.
- A small molecule AMPK activator protects the heart against ischemia-reperfusion injury.
- Discrepancy between GLUT4 translocation and glucose uptake after ischemia.
- Insulin improves postischemic recovery of function through PI3K in isolated working rat heart.
- Experimental model for heart failure in rats--induction and diagnosis.
- Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density.
Doctors Specialties
- Internal Medicine
- Other
Accepted Insurances
Education
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Yale-New Haven Hospital -
Indiana University School of Medicine -
Carol Davila University of Medicine and Pharmacy
Hospital
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Yale-New Haven Hospital
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