Physician
Family Medicine
Dr. Thomas E. Wex, MD
|
|
Give Review
Thomas practices Family Medicine. He went to Vanderbilt University School of Medicine. Thomas is also a published doctor. He has 96 paper published. The most recent paper is: Clinicopathologic implications of MDM2, p53 and K-ras gene alterations in osteosarcomas: MDM2 amplification and p53 mutations found in progressive tumors. He accepts all Medicare patients.
Publications
- Serological assessment of gastric mucosal atrophy in gastric cancer.
- Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa.
- Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.
- Serum Cathepsin K levels are not suitable to differentiate women with chronic bone disorders such as osteopenia and osteoporosis from healthy pre- and postmenopausal w...
- Helicobacter pylori related and non-related lesions in the stomach.
- Identification of clinical and laboratory markers for predicting eosinophilic esophagitis in adults.
- Protease-activated receptor-2 (PAR2) in human gastric mucosa as mediator of proinflammatory effects in Helicobacter pylori infection.
- Expression pattern of cathepsin W isoforms in peripheral blood and gastroesophageal mucosa of patients with gastroesophageal reflux disease.
- Serological prevalence of Helicobacter pylori infection in Saxony-Anhalt, Germany, in 2010.
- Lack of association between gene polymorphisms of Angiotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter p...
- Helicobacter pylori infection and fundic gastric atrophy are not associated with esophageal squamous cell carcinoma: a case-control study.
- Mucosal Progranulin expression is induced by H. pylori, but independent of Secretory Leukocyte Protease Inhibitor (SLPI) expression.
- Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn''s disease.
- Correlation of serum pepsinogens and gastrin-17 with atrophic gastritis in gastroesophageal reflux patients: a matched-pairs study.
- Morphologic, genetic, and biochemical characterization of Helicobacter magdeburgensis, a novel species isolated from the intestine of laboratory mice.
- IL-17A and IL-17F gene expression is strongly induced in the mucosa of H. pylori-infected subjects from Kenya and Germany.
- H. pylori infection is a key risk factor for proximal gastric cancer.
- Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms are not associated with premalignant gastric conditions: a combined haplotype analysis.
- Proteinase-activated receptor-2 in the pathogenesis of gastroesophageal reflux disease.
- Role of regulatory T-cells in H. pylori-induced gastritis and gastric cancer.
- Interleukin 1 beta (IL1B) gene polymorphisms are not associated with gastric carcinogenesis in Germany.
- Impact of endoscopy-based research on quality of life in healthy volunteers.
- Host polymorphisms of immune regulatory genes as risk factors for gastric cancer.
- Influence of cyclooxygenase inhibitors on the function of the prostaglandin transporter organic anion-transporting polypeptide 2A1 expressed in human gastroduodenal mu...
- Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection.
- Zonulin is not increased in the cardiac and esophageal mucosa of patients with gastroesophageal reflux disease.
- Low-dose aspirin has no impact on systemic level of serine protease inhibitors in healthy volunteers.
- Interleukin-1beta and interleukin-8 expression correlate with the histomorphological changes in esophageal mucosa of patients with erosive and non-erosive reflux disease.
- The combined presence of H pylori infection and gastro-oesophageal reflux disease leads to an up-regulation of CDX2 gene expression in antrum and cardia.
- Chronic mucosal inflammation of the gastric cardia in gastroesophageal reflux disease is not regulated by FOXP3-expressing T cells.
- Gastroesophageal reflux disease does not lead to changes in the secretory leukocyte protease inhibitor expression in esophageal mucosa.
- Low-dose aspirin reduces the gene expression of gastrokine-1 in the antral mucosa of healthy subjects.
- Lectin UEA-I-binding proteins are specifically increased in the squamous epithelium of patients with Barrett''s esophagus.
- Regulation of cathepsin X overexpression in H. pylori-infected gastric epithelial cells and macrophages.
- Naturally occurring regulatory T cells (CD4+, CD25high, FOXP3+) in the antrum and cardia are associated with higher H. pylori colonization and increased gene expressio...
- Impact of different anticancer regimens on biomarkers of angiogenesis in patients with advanced hepatocellular cancer.
- Helicobacter pylori infection and short-term intake of low-dose aspirin have different effects on alpha-1 antitrypsin/alpha-1 peptidase inhibitor (alpha1-PI) levels in...
- Short-term/low-dose aspirin-induced duodenal erosions are not dependent on Helicobacter pylori infection, cyclooxygenase expression and prostaglandin E2 levels.
- The long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype--a link to gastric carc...
- Gene polymorphisms of the NOD-2/CARD-15 gene and the risk of gastric cancer in Germany.
- Imatinib for hepatocellular cancer--focus on pharmacokinetic/pharmacodynamic modelling and liver function.
- Gastroesophageal reflux disease leads to major alterations in lectin-binding in the columnar epithelium of the gastroesophageal junction.
- Octreotide alone or in combination with rofecoxib as palliative treatment for advanced hepatocellular cancer.
- Low prevalence of Helicobacteraceae in gall-stone disease and gall-bladder carcinoma in the German population.
- Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer.
- Identification and confirmation of increased fibrinopeptide a serum protein levels in gastric cancer sera by magnet bead assisted MALDI-TOF mass spectrometry.
- Helicobacter pylori-induced downregulation of the secretory leukocyte protease inhibitor (SLPI) in gastric epithelial cell lines and its functional relevance for H. py...
- Impact of biomarkers on disease survival and progression in patients treated with octreotide for advanced hepatocellular carcinoma.
- Effects of low-dose aspirin on gastric erosions, cyclooxygenase expression and mucosal prostaglandin-E2 do not depend on Helicobacter pylori infection.
- Expression of cytokeratins in Helicobacter pylori-associated chronic gastritis of adult patients infected with cagA+ strains: an immunohistochemical study.
- Prevalence and spread of enterohepatic Helicobacter species in mice reared in a specific-pathogen-free animal facility.
- Secretory leukocyte protease inhibitor expression in various types of gastritis: a specific role of Helicobacter pylori infection.
- The association between the interleukin-1 polymorphisms and gastric cancer risk depends on the family history of gastric carcinoma in the study population.
- Helicobacter pylori infection, but not low-dose aspirin, results in a local reduction of the secretory leukocyte protease inhibitor in gastroduodenal mucosa.
- The effect of single-dose naproxen on eicosanoid formation in human gastroduodenal mucosa.
- Helicobacter pylori encoding the pathogenicity island activates matrix metalloproteinase 1 in gastric epithelial cells via JNK and ERK.
- Upregulation of cathepsin W-expressing T cells is specific for autoimmune atrophic gastritis compared to other types of chronic gastritis.
- Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
- Down-regulation of secretory leukocyte protease inhibitor expression in gastric mucosa is a general phenomenon in Helicobacter pylori-related gastroduodenal diseases.
- Identification of a novel isoform predominantly expressed in gastric tissue and a triple-base pair polymorphism of the cathepsin W gene.
- Cathepsins K, L, B, X and W are differentially expressed in normal and chronically inflamed gastric mucosa.
- Identification of enterohepatic Helicobacter species in patients suffering from inflammatory bowel disease.
- TFF3 expression at the esophagogastric junction is increased in gastro-esophageal reflux disease (GERD).
- Anti-CagA and anti-VacA antibodies in Helicobacter pylori-infected patients with and without peptic ulcer disease in Serbia and Montenegro.
- Helicobacter pylori-mediated gastritis induces local downregulation of secretory leukocyte protease inhibitor in the antrum.
- Evaluation of a near-patient fecal antigen test for the assessment of Helicobacter pylori status.
- Diagnostics of Helicobacter pylori infection in patients with peptic ulcer bleeding.
- Simultaneous detection and differentiation of anti-Helicobacter pylori antibodies by flow microparticle immunofluorescence assay.
- Detection of a putative novel Wolinella species in patients with squamous cell carcinoma of the esophagus.
- Functional involvement of cathepsin W in the cytotoxic activity of NK-92 cells.
- A two-step method for the extraction of high-quality RNA from endoscopic biopsies.
- Antigen stool test for assessment of Helicobacter pylori infection in patients with upper gastrointestinal bleeding.
- Plasma leptin and leptin receptor expression in childhood acute lymphoblastic leukemia.
- A group-specific PCR assay for the detection of Helicobacteraceae in human gut.
- Characterization of novel anti-cathepsin W antibodies and cellular distribution of cathepsin W in the gastrointestinal tract.
- Comparative evaluation of two hemagglutination tests for the detection of anti-Helicobacter pylori antibodies.
- Human cathepsin W, a cysteine protease predominantly expressed in NK cells, is mainly localized in the endoplasmic reticulum.
- TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells.
- Human cathepsins W and F form a new subgroup of cathepsins that is evolutionary separated from the cathepsin B- and L-like cysteine proteases.
- Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein.
- The human cathepsin F gene--a fusion product between an ancestral cathepsin and cystatin gene.
- Role of alanyl aminopeptidase in growth and function of human T cells (review).
- Human cathepsins F and W: A new subgroup of cathepsins.
- Clinicopathologic implications of MDM2, p53 and K-ras gene alterations in osteosarcomas: MDM2 amplification and p53 mutations found in progressive tumors.
- Genomic structure, chromosomal localization, and expression of human cathepsin W.
- Identification of point mutations in the aminopeptidase N gene by SSCP analysis and sequencing.
- Antisense-mediated inhibition of aminopeptidase N (CD13) markedly decreases growth rates of hematopoietic tumour cells.
- Activation-dependent induction of T cell alanyl aminopeptidase and its possible involvement in T cell growth.
- The activation-dependent induction of APN-(CD13) in T-cells is controlled at different levels of gene expression.
- Rapid mitogen-induced aminopeptidase N surface expression in human T cells is dominated by mechanisms independent of de novo protein biosynthesis.
- The main neutral aminopeptidase activity of human lymphoid tumour cell lines does not originate from the aminopeptidase N-(APN; CD13) gene.
- Induction of the membrane alanyl aminopeptidase gene and surface expression in human T-cells by mitogenic activation.
- Detection of residual leukemic cells in acute lymphocytic leukemia of B-cells (B-ALL) by a nonradioactive PCR-based technique.
- Expression of the aminopeptidase N (CD13) gene in the human T cell lines HuT78 and H9.
- Quantification of aminopeptidase N mRNA in T cells by competitive PCR.
Schools
Vanderbilt University School Of Medicine
University Wisc Hospital
Doctors Specialties
- Family Medicine
Accepted Insurances
- Choice Plus POS II
- American Enterprise Group
- American Republic
- Assurant Health
- Commercial Insurance Company
- GEHA
- Humana
- Medicaid
- Medical Mutual of Ohio
- Medicare MCR
- Pekin Insurance
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
- Universal American
- Wisconsin Physicians Service
Education
-
Vanderbilt University School of Medicine
Drug Facts
| NPI NUMBER | 1508851825 | |
| NPPES Provider LastName | WEX | |
| NPPES Provider FirstName | THOMAS | |
| NPPES Provider ZIPCode | 549026186 | |
| NPPES Provider State | WI | |
| Specialty Description | Family Practice | |
| Total Claim Count | 409.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1508851825 |
| Last Name Of The Provider | WEX |
| First Name Of The Provider | THOMAS |
| View All |
Similar Doctors
|
|
Dr. Katherine A. O'Rourke, DO
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Michal F. Slovick, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Lance E. Zernzack, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Jon K. Carlson, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Alexey Shereshevsky, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Daniel J. Kaiser, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Karl C. Larson, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Kirsten W. Larson, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Cari A. Bollweg, DO
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Matthew P. Fischer, MD
This Doctor is OpenDoctor Recommended.
|