Physician
Infectious Disease
Dr. Stanley M. Spinola, MD
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Dr. Stanley M. Spinola works in the field of Infectious Disease. He graduated from Georgetown University School of Medicine. Georgetown University School of Medicine has a rank of 49 in research and a 84 in primary care He over the years received 1 awards: "Elected Member". Stanley Spinola is a published doctor as well. He has 92 publications published. The latest was: The immune response to Haemophilus ducreyi resembles a delayed-type hypersensitivity reaction throughout experimental infection of human subjects.
Publications
- Haemophilus ducreyi RpoE and CpxRA appear to play distinct yet complementary roles in regulation of envelope-related functions.
- A (p)ppGpp null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes.
- Permeases of the sap transporter are required for cathelicidin resistance and virulence of Haemophilus ducreyi in humans.
- Sialylation of Lipooligosaccharides Is Dispensable for the Virulence of Haemophilus ducreyi in Humans.
- A Haemophilus ducreyi CpxR Deletion Mutant Is Virulent in Human Volunteers.
- Haemophilus ducreyi Lipooligosaccharides Induce Expression of the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase via Type 1 Interferons and TNF-{alpha} in Human ...
- Activation of the CpxRA system by deletion of cpxA impairs the ability of Haemophilus ducreyi to infect humans.
- Role played by CD4+FOXP3+ regulatory T Cells in suppression of host responses to Haemophilus ducreyi during experimental infection of human volunteers.
- Haemophilus ducreyi SapA contributes to cathelicidin resistance and virulence in humans.
- Mechanism of human natural killer cell activation by Haemophilus ducreyi.
- Inactivation of the Haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects.
- Fatality despite appropriate treatment for babesiosis.
- Experimental infection of human volunteers with Haemophilus ducreyi: fifteen years of clinical data and experience.
- A fibrinogen-binding lipoprotein contributes to the virulence of Haemophilus ducreyi in humans.
- The enterobacterial common antigen-like gene cluster of Haemophilus ducreyi contributes to virulence in humans.
- Evaluation of the repertoire of the TonB-dependent receptors of Haemophilus ducreyi for their role in virulence in humans.
- Outer membrane protein DsrA is the major fibronectin-binding determinant of Haemophilus ducreyi.
- Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers.
- Haemophilus ducreyi partially activates human myeloid dendritic cells.
- Experimental infection with Haemophilus ducreyi in persons who are infected with HIV does not cause local or augment systemic viral replication.
- Expression of Haemophilus ducreyi collagen binding outer membrane protein NcaA is required for virulence in swine and human challenge models of chancroid.
- A DltA mutant of Haemophilus ducreyi Is partially attenuated in its ability to cause pustules in human volunteers.
- Trafficking pathways and characterization of CD4 and CD8 cells recruited to the skin of humans experimentally infected with Haemophilus ducreyi.
- Expression of the LspA1 and LspA2 proteins by Haemophilus ducreyi is required for virulence in human volunteers.
- Haemophilus ducreyi requires an intact flp gene cluster for virulence in humans.
- Differences in host susceptibility to disease progression in the human challenge model of Haemophilus ducreyi infection.
- CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking.
- Evolution of the cutaneous immune response to experimental Haemophilus ducreyi infection and its relevance to HIV-1 acquisition.
- Immunopathogenesis of Haemophilus ducreyi infection (chancroid).
- A superoxide dismutase C mutant of Haemophilus ducreyi is virulent in human volunteers.
- Men are more susceptible than women to pustule formation in the experimental model of Haemophilus ducreyi infection.
- Haemophilus ducreyi: clinical disease and pathogenesis.
- Draft Whole-Genome Sequence of Haemophilus ducreyi Strain AUSPNG1, Isolated from a Cutaneous Ulcer of a Child from Papua New Guinea.
- Correcting imbalanced reads coverage in bacterial transcriptome sequencing with extreme deep coverage.
- Characterization of Haemophilus ducreyi-specific T-cell lines from lesions of experimentally infected human subjects.
- Haemophilus ducreyi lipooligosaccharide mutant defective in expression of beta-1,4-glucosyltransferase is virulent in humans.
- Haemophilus ducreyi associates with phagocytes, collagen, and fibrin and remains extracellular throughout infection of human volunteers.
- Expression of cytolethal distending toxin and hemolysin is not required for pustule formation by Haemophilus ducreyi in human volunteers.
- DsrA-deficient mutant of Haemophilus ducreyi is impaired in its ability to infect human volunteers.
- Transcription of candidate virulence genes of Haemophilus ducreyi during infection of human volunteers.
- Expression of peptidoglycan-associated lipoprotein is required for virulence in the human model of Haemophilus ducreyi infection.
- Evaluation of an isogenic major outer membrane protein-deficient mutant in the human model of Haemophilus ducreyi infection.
- Localization of Haemophilus ducreyi at the pustular stage of disease in the human model of infection.
- A pilus-deficient mutant of Haemophilus ducreyi is virulent in the human model of experimental infection.
- An isogenic hemoglobin receptor-deficient mutant of Haemophilus ducreyi is attenuated in the human model of experimental infection.
- Cumulative experience with Haemophilus ducreyi 35000 in the human model of experimental infection.
- Cytolethal distending toxin of Haemophilus ducreyi induces apoptotic death of Jurkat T cells.
- Expression of sialylated or paragloboside-like lipooligosaccharides are not required for pustule formation by Haemophilus ducreyi in human volunteers.
- Binding of Haemophilus ducreyi to extracellular matrix proteins.
- Experimental infection of human volunteers with Haemophilus ducreyi does not confer protection against subsequent challenge.
- Effect of normal and immune sera on Haemophilus ducreyi 35000HP and its isogenic MOMP and LOS mutants.
- The immune response to Haemophilus ducreyi resembles a delayed-type hypersensitivity reaction throughout experimental infection of human subjects.
- Standardization of the experimental model of Haemophilus ducreyi infection in human subjects.
- Haemophilus ducreyi is susceptible to protegrin.
- Evaluation of an isogenic hemolysin-deficient mutant in the human model of Haemophilus ducreyi infection.
- Prevention of experimental Haemophilus ducreyi infection: a randomized, controlled clinical trial.
- Comparison of enzyme immunoassays for antibodies to Haemophilus ducreyi in a community outbreak of chancroid in the United States.
- The major outer membrane protein of Haemophilus ducreyi consists of two OmpA homologs.
- Characterization of a novel lipoprotein expressed by Haemophilus ducreyi.
- The conserved 18,000-molecular-weight outer membrane protein of Haemophilus ducreyi has homology to PAL.
- Haemophilus ducreyi elicits a cutaneous infiltrate of CD4 cells during experimental human infection.
- Fine tangled pili expressed by Haemophilus ducreyi are a novel class of pili.
- The major outer membrane protein of Haemophilus ducreyi is a member of the OmpA family of proteins.
- Experimental human infection with Haemophilus ducreyi.
- Haemophilus ducreyi adheres to human keratinocytes.
- Pyopneumothorax in a 14-year-old boy.
- Actinomycosis. A cause of pulmonary and mediastinal mass lesions in children.
- Childhood sarcoidosis.
- Different blocking agents cause variation in the immunologic detection of proteins transferred to nitrocellulose membranes.
- Antigenuria after Haemophilus influenzae type b polysaccharide immunization: a prospective study.
- Epidemiology of colonization by nontypable Haemophilus influenzae in children: a longitudinal study.
- Antigenuria after Haemophilus influenzae type b polysaccharide vaccination.
- Conserved lipoprotein H.8 of pathogenic Neisseria consists entirely of pentapeptide repeats.
- The H8 antigen of pathogenic Neisseriae.
- Localization of a conserved epitope and an azurin-like domain in the H.8 protein of pathogenic Neisseria.
- Characterization of pili expressed by Haemophilus ducreyi.
- Role of lipooligosaccharides in experimental dermal lesions caused by Haemophilus ducreyi.
- Analysis of Haemophilus influenzae type b lipooligosaccharide-synthesis genes that assemble or expose a 2-keto-3-deoxyoctulosonic acid epitope.
- Lipooligosaccharide epitopes shared among gram-negative non-enteric mucosal pathogens.
- Cloning and expression in Escherichia coli of a Haemophilus influenzae type b lipooligosaccharide synthesis gene(s) that encodes a 2-keto-3-deoxyoctulosonic acid epitope.
- Localization of and immune response to the lipid-modified azurin of the pathogenic Neisseria.
- Generation of lipooligosaccharide mutants of Haemophilus influenzae type b.
- Cloning and analysis of lipooligosaccharide synthesis genes of Haemophilus influenzae type b that assemble or expose a 2-keto-3-deoxyoctulosonic acid epitope in Escher...
- Lipooligosaccharides (LOS) of some Haemophilus species mimic human glycosphingolipids, and some LOS are sialylated.
- Characterization of an 18,000-molecular-weight outer membrane protein of Haemophilus ducreyi that contains a conserved surface-exposed epitope.
- Expression of pili by Haemophilus ducreyi.
- The effects of phenytoin and lidocaine on a proprioceptor of the cockroach, Blaberus discoidalis: a simple method for discriminating between inhibitors of sensory tran...
- Haemophilus ducreyi: clinical features, epidemiology, and prospects for disease control.
- Expression of OmpP2A and OmpP2B is not required for pustule formation by Haemophilus ducreyi in human volunteers.
- Identification of Haemophilus ducreyi genes expressed during human infection.
- Localization of Haemophilus ducreyi in naturally acquired chancroidal ulcers.
Schools
Georgetown University
North Carolina Memorial Hospital
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Awards
- Elected Member
Education
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University of North Carolina Hospitals -
Georgetown University School of Medicine
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