Professor, Pediatrics, UCSF School of Medicine
Pediatrics
Dr. Scott J. Soifer, MD
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Scott J. Soifer, MD practices Pediatrics. He researched medicine at State University of New York Upstate Medical University. Dr. Scott J. Soifer is a published physician as well. He has 51 publications published. The latest was: Coordinated regulation of genes of the nitric oxide and endothelin pathways during the development of pulmonary hypertension in fetal lambs.
Publications
- Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary Hypertension.
- Cyclic mechanical stretch induces VEGF and FGF-2 expression in Pulmonary vascular smooth muscle cells.
- Effect of enalaprilat on postoperative hypertension after surgical repair of Coarctation of the aorta.
- Altered regulation of the ET-1 cascade in lambs with increased pulmonary blood flow and pulmonary Hypertension.
- Increased endothelial NOS in lambs with increased pulmonary blood flow and pulmonary Hypertension.
- Increased Pulmonary blood flow alters the molecular regulation of vascular reactivity in the lamb.
- Altered endothelial function in lambs with pulmonary Hypertension and acute lung injury.
- Coordinated regulation of genes of the nitric oxide and endothelin pathways during the development of pulmonary Hypertension in fetal lambs.
- EDRF inhibition attenuates the increase in Pulmonary blood flow due to oxygen ventilation in fetal lambs.
- Selective pulmonary vasodilation with ATP-MgCl2 during pulmonary Hypertension in lambs.
- EDRF inhibition augments pulmonary Hypertension in intact newborn lambs.
- Endothelinb receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary Hypertension.
- M&B 22948, a cGMP phosphodiesterase inhibitor, is a Pulmonary vasodilator in lambs.
- Chronic nitric oxide inhibition in utero produces persistent pulmonary Hypertension in newborn lambs.
- HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary Hypertension in newborn lambs.
- A receptor for vascular endothelial growth factor that stimulates endothelial apoptosis.
- Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs.
- Hyperoxia and alkalosis produce Pulmonary vasodilation independent of endothelium-derived nitric oxide in newborn lambs.
- Diethylamine/nitric oxide (NO) adduct, an NO donor, produces potent Pulmonary and systemic vasodilation in intact newborn lambs.
- L-Arginine, a precursor of EDRF in vitro, produces Pulmonary vasodilation in lambs.
- N omega-nitro-L-arginine attenuates endothelium-dependent Pulmonary vasodilation in lambs.
- Use of ATP-MgCl2 in the evaluation and treatment of children with pulmonary hypertension secondary to Congenital heart defects.
- K+ channel Pulmonary vasodilation in fetal lambs: role of endothelium-derived nitric oxide.
- Developmental effects of endothelin-1 on the Pulmonary circulation in sheep.
- Endothelin-1 produces Pulmonary vasodilation in the intact newborn lamb.
- Effects of vasoactive drugs on thromboxane A2 mimetic-induced pulmonary Hypertension in newborn lambs.
- In vivo attenuation of endothelium-dependent Pulmonary vasodilation by methylene blue.
- Piriprost: a putative leukotriene synthesis inhibitor increases Pulmonary blood flow in fetal lambs.
- Cromolyn sodium does not prevent hypoxia-induced pulmonary Hypertension in newborn and young lambs.
- The role of Pulmonary vascular endothelium in perinatal Pulmonary circulatory regulation.
- Endothelin-1 does not mediate acute hypoxic Pulmonary vasoconstriction in the intact newborn lamb.
- Expression of neuronal nitric oxide synthase corresponds to regions of selective vulnerability to hypoxia-ischaemia in the developing rat brain.
- Bradykinin produces Pulmonary vasodilation in fetal lambs: role of prostaglandin production.
- Leukotriene end organ antagonists increase Pulmonary blood flow in fetal lambs.
- Umbilical cord compression produces pulmonary Hypertension in newborn lambs: a model to study the pathophysiology of persistent pulmonary Hypertension in the newborn.
- Leukotrienes C4, D4, and E4 in fetal lamb tracheal fluid.
- Pulmonary hypertension: physiologic or pathologic Disease?
- Tricuspid regurgitation in children: a pulsed Doppler, contrast echocardiographic and angiographic comparison.
- Thromboxane is not responsible for the high Pulmonary vascular resistance in fetal lambs.
- The differential effects of leukotriene C4 and D4 on the Pulmonary and systemic circulations in newborn lambs.
- Regulation of Pulmonary vascular tone in the perinatal period.
- Future research directions in persistent pulmonary Hypertension of the newborn.
- Synthetic patch aortoplasty. A simplified approach for Coarctation in repairs during early infancy and thereafter.
- Thrombin receptor expression in normal and atherosclerotic human arteries.
- Leukotriene antagonists attenuate thromboxane-inducible pulmonary Hypertension.
- Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development.
- Prostaglandin D2 reverses induced pulmonary Hypertension in the newborn lamb.
- Leukotriene synthesis inhibition increases Pulmonary blood flow in fetal lambs.
- Hemodynamic effects of oleic acid in newborn lambs: role of arachidonic acid metabolites.
- Increased arterial pH, not decreased PaCO2, attenuates hypoxia-induced Pulmonary vasoconstriction in newborn lambs.
Schools
SUNY Upstate Medical University Syracuse
Yale New Haven Hospital
Procedures Preformed
- Cardiac Imaging
- Chest CT (incl. Heart and Lungs)
Conditions Treated
- Aortic Valve Disease
- Arrhythmias (incl. Atrial Fibrillation)
- Autonomic Disorders
- Cardiomegaly
- View All
Doctors Specialties
- Pediatric Cardiology
- Pediatric Critical Care Medicine
- Pediatrics
Accepted Insurances
Education
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Yale-New Haven Hospital -
State University of New York Upstate Medical University
Hospital
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UCSF Medical Center
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