Melanoma Section Chief. Professor, City of Hope National Medical Center and Beckman Research Institute Departments of Medical Oncology and Diabetes, Endocrinology and Metabolism
Oncology
Dr. Sanjay Awasthi, MD
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Sanjay Awasthi practices Oncology. He researched medicine at University of Arkansas for Medical Sciences. University of Arkansas for Medical Sciences is ranked 83/35 in Research/PrimaryCare. He received awards:"Regional Top Doctor", "Young Scientist Award", "Oncology Training Fellowship Award" and "Phi Eta Sigma Honor Society". Sanjay Awasthi, MD is a published doctor. He published 51 publications, including: 'RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes.' He accepts all Medicare patients.
Publications
- RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes.
- Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling.
- LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells.
- Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung Cancer progression.
- Lens specific RLIP76 transgenic mice show a phenoType similar to microphthalmia.
- 4-Hydroxynonenal Induces G2/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Sign...
- Regression of Lung Cancer by Hypoxia Sensitizing Ruthenium Polypyridyl Complexes.
- P300 Regulates the Human RLIP76 Promoter Activity and Gene Expression.
- Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma.
- 1,3-Bis(3,5-dichlorophenyl) urea compound 'COH-SR4' inhibits proliferation and activates apoptosis in melanoma.
- RALBP1/RLIP76 Depletion in Mice Suppresses Tumor Growth by Inhibiting Tumor Neovascularization.
- RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer.
- COH-SR4 Reduces Body Weight, Improves Glycemic Control and Prevents Hepatic Steatosis in High Fat Diet-Induced Obese Mice.
- Proteomic analysis of signaling network regulation in renal cell carcinomas with differential hypoxia-inducible factor-2α expression.
- Role of SMC1 in Overcoming Drug Resistance in Triple Negative Breast Cancer.
- The role of PKCalpha and RLIP76 in transport-mediated doxorubicin-resistance in lung Cancer.
- Role of RLIP76 in lung Cancer doxorubicin resistance: II. Doxorubicin transport in lung Cancer by RLIP76.
- Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney Cancer.
- Role of RLIP76 in lung Cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung Cancer cells and synergistically increase doxorubicin cytot...
- POB1 over-expression inhibits RLIP76-mediated transport of glutathione-conjugates, drugs and promotes apoptosis.
- Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosis.
- Inhibition of mercapturic acid pathway-mediated disposal of 4-hydroxynonenal causes complete and sustained remission of human Cancer xenografts in nude mice.
- Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells.
- Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling.
- Role of Lipid peroxidation in cellular responses to D,L-sulforaphane, a promising cancer chemopreventive agent.
- Physiological and pharmacological significance of glutathione-conjugate transport.
- 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells.
- RLIP76 in defense of radiation poisoning.
- Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death.
- 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.
- RLIP76 in AED drug resistance.
- The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance.
- Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal.
- Glutathione S-transferases as antioxidant enzymes: small cell lung Cancer (H69) cells transfected with hGSTA1 resist doxorubicin-induced apoptosis.
- RLIP76 (RALBP1)-mediated transport of leukotriene C4 (LTC4) in Cancer cells: implications in drug resistance.
- Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells.
- Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis.
- Role of 4-hydroxynonenal in stress-mediated apoptosis signaling.
- Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated si...
- Mechanisms and physiological significance of the transport of the glutathione conjugate of 4-hydroxynonenal in human lens epithelial cells.
- Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): a novel link between G-protein and tyrosine kinase signaling and drug resistance.
- Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling.
- Energy dependent transport of xenobiotics and its relevance to multidrug resistance.
- RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobiotics.
- Functional reconstitution of Ral-binding GTPase activating protein, RLIP76, in proteoliposomes catalyzing ATP-dependent transport of glutathione conjugate of 4-hydroxy...
- Protection of HLE B-3 cells against hydrogen peroxide- and naphthalene-induced Lipid peroxidation and apoptosis by transfection with hGSTA1 and hGSTA2.
- Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression.
- Transport functions and physiological significance of 76 kDa Ral-binding GTPase activating protein (RLIP76).
- Role of RLIP76 in lung Cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung Cancer cells.
- The relationship of doxorubicin binding to membrane Lipids with drug resistance.
Schools
University Of Arkansas Of Medical Sciences
The University Of Texas Medical Branch
Conditions Treated
- Calcium Metabolism Disorders
- Diabetes
- Diabetes Mellitus, Secondary
- Diabetes Type 2
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Doctors Specialties
- Oncology
Accepted Insurances
Awards
- Regional Top Doctor
- Young Scientist Award
- Oncology Training Fellowship Award
- Phi Eta Sigma Honor Society
Education
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University of Arkansas for Medical Sciences -
University of Texas Southwestern Medical School
Hospital
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Medical Center Arlington -
Huntington Memorial Hospital -
City of Hope's Helford Clinical Research Hospital
Drug Facts
| NPI NUMBER | 1518904077 | |
| NPPES Provider LastName | AWASTHI | |
| NPPES Provider FirstName | SANJAY | |
| NPPES Provider ZIPCode | 910103000 | |
| NPPES Provider State | CA | |
| Specialty Description | Medical Oncology | |
| Total Claim Count | 62.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1518904077 |
| Last Name Of The Provider | AWASTHI |
| First Name Of The Provider | SANJAY |
| View All |
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