Physician
Internal Medicine
Dr. Sami N. Malek, MD
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Sami N. Malek, MD works in the field of Internal Medicine. He graduated from Baylor College of Medicine. He over the years received 1 awards: "CMS Meaningful Use Stage 1 Certification". Sami Malek is a published MD as well. He has 48 publications published. The latest was: Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase. He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner.
- Targeting deubiquitinase activity with a novel small molecule inhibitor as therapy for B-Cell malignancies.
- INTEGRATED GENOMIC PROFILING, THERAPY RESPONSE AND SURVIVAL IN ADULT Acute MYELOGENOUS LEUKEMIA.
- Activating STAT6 mutations in follicular Lymphoma.
- Genetics of Follicular Lymphoma Transformation.
- Mutations in linker histone genes HIST1H1 B, C, D and E, OCT2 (POU2F2), IRF8 and ARID1A underlying the pathogenesis of follicular Lymphoma.
- Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia.
- Clonal evolution, genomic drivers, and effects of therapy in chronic lymphocytic Leukemia.
- Analysis of acquired genomic copy number aberrations and regions of loss of heterozygosity in Acute myelogenous leukemia genomes using affymetrix SNP 6.0 arrays and su...
- Incidence and clinical implications of ATM aberrations in chronic lymphocytic Leukemia.
- Clonal evolution and devolution following chemotherapy in adult Acute myelogenous leukemia.
- Somatic mutations in the chromatin remodeling gene ARID1A occur in seVeral tumor types.
- Somatic mutations in the transcriptional corepressor gene BCORL1 in adult Acute myelogenous leukemia.
- The prognostic significance of various 13q14 deletions in chronic lymphocytic Leukemia.
- Acquired genomic copy number aberrations and survival in chronic lymphocytic Leukemia.
- A pathobiological role of the insulin receptor in chronic lymphocytic Leukemia.
- Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies.
- Biomarkers in NHL.
- Acquired genomic copy number aberrations and survival in adult Acute myelogenous leukemia.
- NF1 inactivation in adult Acute myelogenous leukemia.
- Multiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult Acute myelogenous leukemia.
- Aggressive chronic lymphocytic Leukemia with elevated genomic complexity is associated with multiple gene defects in the response to DNA double-strand breaks.
- Genomic complexity identifies patients with aggressive chronic lymphocytic Leukemia.
- The pre-clinical development of MDM2 inhibitors in chronic lymphocytic Leukemia uncovers a central role for p53 status in sensitivity to MDM2 inhibitor-mediated apopto...
- Integrated genomic profiling of chronic lymphocytic Leukemia identifies subtypes of deletion 13q14.
- Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic Leukemia.
- Comprehensive analysis of copy number and allele status identifies multiple chromosome defects underlying follicular Lymphoma pathogenesis.
- Incorporating monoclonal antibodies in blood and marrow transplantation.
- MALT Lymphomas.
- Acquired Genomic Copy Number Aberrations in CLL.
- Molecular biomarkers in chronic lymphocytic Leukemia.
- Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic Leukemia B cells.
- Commentary: topoisomerases as targets in Acute leukemia: I, II, I plus II or none?
- p53 stabilization induces apoptosis in chronic myeloid Leukemia blast crisis cells.
- Multi-institutional Phase II clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed Acute myelogenous leukemia.
- Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic Leukemia B-cells.
- A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand.
- Identification and preliminary characterization of two related proliferation-associated nuclear phosphoproteins.
- Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase.
- p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains.
- An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo.
- SH2 domains of the protein-tyrosine kinases Blk, Lyn, and Fyn(T) bind distinct sets of phosphoproteins from B lymphocytes.
- Sequence analysis of 515 kinase genes in chronic lymphocytic Leukemia.
- Emergency repair of groin herniae: outcome and implications for elective surgery waiting times.
- Tandem SH2 domains of ZAP-70 bind to T Cell antigen receptor zeta and CD3 epsilon from activated Jurkat T Cells.
- [Sinus heart rate variability after a myocardial infarction].
- [Cardiogenic shock in the Acute phase of myocardial infarction].
Schools
University of Hamburg Medical Faculty
Baylor College Of Med
Sidney Kimmel Canc Center Johns Hopkins Hospital
Procedures Preformed
- Plasmapheresis
- Thoracentesis
Conditions Treated
- Acute Leukemia
- Anemia
- Basal Cell Carcinoma
- Bladder Cancer
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Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
- Internal Medicine
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Johns Hopkins University -
Baylor College of Medicine
Hospital
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University of Michigan Hospitals and Health Centers
Drug Facts
| NPI NUMBER | 1831275791 | |
| NPPES Provider LastName | MALEK | |
| NPPES Provider FirstName | SAMI | |
| NPPES Provider ZIPCode | 481095911 | |
| NPPES Provider State | MI | |
| Specialty Description | Hematology | |
| Total Claim Count | 57.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1831275791 |
| Last Name Of The Provider | MALEK |
| First Name Of The Provider | SAMI |
| View All |
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