Professor, Pediatrics, UC, Davis School of Medicine
Pediatric Pulmonology
Dr. Ruth J. McDonald, MD
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Ruth J. McDonald, MD works in the field of Pediatric Pulmonology. She researched medicine at Oregon Health & Science University School of Medicine. She received 1 awards: "Fellow (FAAP)". Ruth McDonald is a published doctor and has 25 publications published. The lastest was: 'Aerosol delivery of lipid:DNA complexes to lungs of rhesus monkeys.'
Publications
- Postnatal episodic ozone results in persistent attenuation of pulmonary and peripheral blood responses to LPS challenge.
- Persistent rhinitis and epithelial remodeling induced by cyclic ozone exposure in the nasal airways of infant monkeys.
- Five-fold increase in pediatric parapneumonic empyema since introduction of pneumococcal conjugate vaccine.
- Effect of secondhand cigarette smoke, RSV bronchiolitis and parental asthma on urinary cysteinyl LTE4.
- Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery.
- Immunostimulatory oligonucleotides attenuate airways remodeling in allergic monkeys.
- Antibiotic sampling from central venous catheters versus peripheral veins.
- Hydrogen peroxide induces DNA single strand breaks in respiratory epithelial cells.
- Neutrophils injure bronchial epithelium after ozone exposure.
- Pharmacologic management of the hospitalized pediatric asthma patient.
- Eosinophils cause acute edematous injury in isolated perfused rat lungs.
- Time course of ozone-induced neutrophilia in normal humans.
- Expression of mucin synthesis and secretion in human tracheobronchial epithelial cells grown in culture.
- Safety of airway gene transfer with Ad2/CFTR2: aerosol administration in the nonhuman primate.
- Effects of ozone and neutrophils on function and morphology of the isolated rat lung.
- Substance P primes the formation of hydrogen peroxide and nitric oxide in human neutrophils.
- Trafficking of neutrophils across airway epithelium is dependent upon both thioredoxin- and pertussis toxin-sensitive signaling mechanisms.
- Neutrophil adherence to airway epithelium is reduced by antibodies to the leukocyte CD11/CD18 complex.
- Aerosol delivery of lipid:DNA complexes to lungs of rhesus monkeys.
- Functional and morphologic changes caused by acute ozone exposure in the isolated and perfused rat lung.
- Ozone effects on mechanics and arachidonic acid metabolite concentrations in isolated rat lungs.
- Neutrophils enhance removal of ozone-injured alveolar epithelial cells in vitro.
- Neutrophils enhance clearance of necrotic epithelial cells in ozone-induced lung injury in rhesus monkeys.
- DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor.
Schools
Oregon Health And Science University School Of Medicine
University Colo Health Science Center
Oregon Health and Science University
University Colo Hsc
Conditions Treated
- Cystic Fibrosis
Doctors Specialties
- Pediatric Pulmonology
Accepted Insurances
Awards
- Fellow (FAAP)
Education
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Oregon Health & Science University -
University of Colorado -
Oregon Health & Science University School of Medicine
Hospital
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University of California, Davis Medical Center
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