Professor of Medicine Chief, Division of Endocrinology
Endocrinology
Dr. Ronald M. Lechan, MD
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Dr. Ronald M. Lechan is an expert in the field of Endocrinology. He graduated from University of Vermont College of Medicine. He received 6 awards: "America's Top Doctors", "Boston Magazine", "CMS Meaningful Use Stage 1 Certification", "Boston Herald", "Elected Member" and "Super Doctor". Ronald Lechan has written publications. He has 101 publications published with PubMed. The lastest publication is: 'Synthesis of luteinising hormone releasing factor and thyrotropin-releasing factor in glutamate-lesioned mice.' He accepts Medicare payments and is registered with Medicare.gov.
Publications
- Parallel Regulation of Thyroid Hormone Transporters OATP1c1 and MCT8 During and After Endotoxemia at the Blood-Brain Barrier of Male Rodents.
- Inflammation-inducible Type 2 deiodinase expression in the leptomeninges, choroid plexus and at brain blood vessels in male rodents.
- Pancreatic neuroendocrine tumor With ectopic adrenocorticotropin production: a case report and review of literature.
- Distinct glutamatergic and GABAergic subsets of hypothalamic proopiomelanocortin neurons revealed by in situ hybridization in male rats and mice.
- New Syndrome of paraganglioma and somatostatinoma associated with polycythemia.
- Refeeding-Activated Glutamatergic Neurons in the Hypothalamic Paraventricular Nucleus (PVN) Mediate Effects of Melanocortin Signaling in the Nucleus Tractus Solitarius...
- Inhibition of the Type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment.
- Distribution of hypophysiotropic thyrotropin-releasing Hormone (TRH)-synthesizing neurons in the hypothalamic paraventricular nucleus of the mouse.
- Contribution of TNF-alpha and nuclear factor-kappaB signaling to Type 2 iodothyronine deiodinase activation in the mediobasal hypothalamus after lipopolysaccharide adm...
- Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
- Distribution and axonal projections of neurons coexpressing thyrotropin-releasing Hormone and urocortin 3 in the rat brain.
- Neurogenin 3-specific dipeptidyl peptidase-2 Deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity.
- Efferent projections of thyrotropin-releasing Hormone-synthesizing neurons residing in the anterior parvocellular subdivision of the hypothalamic paraventricular nucleus.
- Tanycyte pyroglutamyl peptidase II contributes to regulation of the hypothalamic-pituitary-Thyroid axis through glial-axonal associations in the median eminence.
- Type 1 cannabinoid receptor-containing axons innervate hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons.
- Differential effects of refeeding on melanocortin-responsive neurons in the hypothalamic paraventricular nucleus.
- Induction of Type 2 iodothyronine deiodinase in the mediobasal hypothalamus by bacterial lipopolysaccharide: role of corticosterone.
- Mitogen-activated protein kinase contributes to lipopolysaccharide-induced activation of corticotropin-releasing Hormone synthesizing neurons in the hypothalamic parav...
- Importance of cocaine- and amphetamine-regulated transcript peptide in the central nucleus of amygdala in anxiogenic responses induced by ethanol Withdrawal.
- Contribution of noradrenergic and adrenergic cell groups of the brainstem and agouti-related protein-synthesizing neurons of the arcuate nucleus to neuropeptide-y inne...
- Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of Type 2 deiodinase in the rat brain.
- Cocaine- and amphetamine-regulated transcript (CART) is colocalized With the orexigenic neuropeptide Y and agouti-related protein and absent from the anorexigenic alph...
- Negative feedback regulation of hypophysiotropic thyrotropin-releasing hormone (TRH) synthesizing neurons: role of neuronal afferents and Type 2 deiodinase.
- Immunohistochemical localization of cocaine- and amphetamine-regulated transcript peptide in the brain of the catfish, Clarias batrachus (Linn.).
- Importance of melanocortin signaling in refeeding-induced neuronal activation and satiety.
- Temozolomide in the treatment of an invasive prolactinoma resistant to dopamine agonists.
- Central mechanisms for Thyroid hormone regulation.
- Neuroendocrine implications for the association between cocaine- and amphetamine regulated transcript (CART) and hypophysiotropic thyrotropin-releasing Hormone (TRH).
- Atypical expression of Type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism.
- Role of melanocortin signaling in the regulation of the hypothalamic-pituitary-Thyroid (HPT) axis.
- Differential effects of central leptin, insulin, or glucose administration during fasting on the hypothalamic-pituitary-Thyroid axis and feeding-related neurons in the...
- Role of Thyroid hormone deiodination in the hypothalamus.
- Origin of cocaine- and amphetamine-regulated transcript-containing axons innervating hypophysiotropic corticotropin-releasing Hormone-synthesizing neurons in the rat.
- Ascending brainstem pathways are not involved in lipopolysaccharide-induced suppression of thyrotropin-releasing Hormone gene expression in the hypothalamic paraventri...
- Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-Thyroid axis in the melanocortin 4 receptor knockout mouse.
- Cocaine- and amphetamine-regulated transcript co-contained in thyrotropin-releasing Hormone (TRH) neurons of the hypothalamic paraventricular nucleus modulates TRH-ind...
- Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: implications for the nonThyroidal illness syndrome.
- Origin of cocaine- and amphetamine-regulated transcript (CART)-immunoreactive innervation of the hypothalamic paraventricular nucleus.
- Hypertensive crisis inducing rhabdomyolysis during laparoscopic resection of a large pheochromocytoma: a case report.
- Central administration of neuropeptide Y reduces alpha-melanocyte-stimulating Hormone-induced cyclic adenosine 5'-monophosphate response element binding protein (CREB)...
- Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-Thyroid axis.
- Agouti-related protein (AGRP) has a central inhibitory action on the hypothalamic-pituitary-Thyroid (HPT) axis; comparisons between the effect of AGRP and neuropeptide...
- VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-contain...
- Corticotropin-releasing Hormone-synthesizing neurons of the human hypothalamus receive neuropeptide Y-immunoreactive innervation from neurons residing primarily outsid...
- Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires Type 2 deiodinase.
- Noradrenergic innervation of hypophysiotropic thyrotropin-releasing Hormone-synthesizing neurons in rats.
- The dilemma of the nonThyroidal illness syndrome.
- Type 2 iodothyronine deiodinase is highly expressed in germ cells of adult rat testis.
- Cocaine- and amphetamine-regulated transcript (CART) expression is differentially regulated in the hypothalamic paraventricular nucleus of lactating rats exposed to su...
- Regulation of cocaine- and amphetamine-regulated transcript-synthesising neurons of the hypothalamic paraventricular nucleus by endotoxin; implications for lipopolysac...
- Association of cocaine- and amphetamine-regulated transcript and neuropeptide Y in the forebrain and pituitary of the catfish, Clarias batrachus: a double immunofluore...
- Endocrinology and art. Acromegaly and goiter in the Pre-Columbian, Mesoamerican population.
- Infundibular tanycytes as modulators of neuroendocrine function: hypothetical role in the regulation of the Thyroid and gonadal axis.
- The TRH neuron: a hypothalamic integrator of energy Metabolism.
- Goiter in the court of the Byzantine Empress, Theodora.
- Bacterial lipopolysaccharide (LPS)-induced Type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall ...
- Neuroanatomical evidence for participation of the hypothalamic dorsomedial nucleus (DMN) in regulation of the hypothalamic paraventricular nucleus (PVN) by alpha-melan...
- Relative contribution of brainstem afferents to the cocaine- and amphetamine-regulated transcript (CART) innervation of thyrotropin-releasing Hormone synthesizing neur...
- Glutamatergic innervation of corticotropin-releasing Hormone- and thyrotropin-releasing Hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the...
- Feedback regulation of thyrotropin-releasing hormone (TRH): mechanisms for the non-Thyroidal illness syndrome.
- Central administration of cocaine- and amphetamine-regulated transcript increases phosphorylation of cAMP response element binding protein in corticotropin-releasing h...
- Galanin- but not galanin-like peptide-containing axon terminals innervate hypophysiotropic TRH-synthesizing neurons in the hypothalamic paraventricular nucleus.
- Medullary adrenergic neurons contribute to the cocaine- and amphetamine-regulated transcript-immunoreactive innervation of thyrotropin-releasing Hormone synthesizing n...
- New paradigms in neuroendocrinology: relationships between obesity, systemic inflammation and the neuroendocrine system.
- Glucagon like peptide-1 (7-36) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing Hormone neurons in the hypothalamic paraventricular nucleus.
- GABA-ergic innervation of thyrotropin-releasing Hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat.
- Effect of precipitated morphine Withdrawal on post-translational processing of prothyrotropin releasing hormone (proTRH) in the ventrolateral column of the midbrain pe...
- Medullary adrenergic neurons contribute to the neuropeptide Y-ergic innervation of hypophysiotropic thyrotropin-releasing Hormone-synthesizing neurons in the rat.
- Intracerebroventricular administration of alpha-melanocyte stimulating Hormone increases phosphorylation of CREB in TRH- and CRH-producing neurons of the hypothalamic ...
- Synthesis of luteinising Hormone releasing factor and thyrotropin-releasing factor in glutamate-lesioned mice.
- Feedback regulation of thyrotropin-releasing hormone gene expression by Thyroid hormone in the hypothalamic paraventricular nucleus.
- Transient thyrotoxicosis and persistent hypoThyroidism due to acute autoimmune Thyroiditis after interleukin-2 and interferon-alpha therapy for metastatic carcinoma: a...
- Thyrotropin-releasing Hormone gene expression in the hypothalamic paraventricular nucleus is dependent upon feedback regulation by both triiodothyronine and thyroxine.
- HypoThyroidism increases vasoactive intestinal polypeptide (VIP) immunoreactivity and gene expression in the rat hypothalamic paraventricular nucleus.
- Gomori-positive astrocytes in primary culture: effects of in vitro age and cysteamine exposure.
- Thyrotropin-releasing-Hormone-immunoreactive innervation of thyrotropin-releasing-Hormone-tuberoinfundibular neurons in rat hypothalamus: anatomical basis to suggest u...
- Expression of Thyroid hormone receptor beta 2 in rat hypothalamus.
- Muscle denervation increases thyrotropin-releasing Hormone (TRH) biosynthesis in the rat medullary raphe.
- 1-naphthol-pyronin B as a novel substrate for silver intensification: application to light and electron microscopic immunocytochemistry of neuroendocrine systems.
- Neuropeptide-Y-immunoreactive innervation of thyrotropin-releasing Hormone-synthesizing neurons in the rat hypothalamic paraventricular nucleus.
- proTRH gene expression by fetal pancreatic islets in culture.
- Estrogen regulates the gene expression of vasoactive intestinal peptide in the anterior pituitary.
- Isolated adrenocorticotropin deficiency associated With an autoantibody to a corticotroph antigen that is not adrenocorticotropin or other proopiomelanocortin-derived ...
- Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide.
- Glial peroxidase activity in the hypothalamic arcuate nucleus: effects of estradiol valerate-induced persistent estrus.
- Immunoreactive interleukin-1 beta localization in the rat forebrain.
- Immunoreactive neuronal pathways of Growth hormone-releasing hormone (GRH) in the brain and pituitary of the teleost Gadus morhua.
- In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes.
- Localization of somatostatin mRNA in the gut, pancreas and Thyroid gland of the rat using antisense RNA probes for in situ hybridization.
- Pro-TRH gene expression and precursor peptides in rat brain. Observations by hybridization analysis and immunocytochemistry.
- TRH and Diseases of the motor system.
- Thyroid hormone regulates vasoactive intestinal peptide (VIP) mRNA levels in the rat anterior pituitary gland.
- Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice.
- Hypophysiotrophic thyrotropin releasing Hormone (TRH) synthesizing neurons. Ultrastructure, adrenergic innervation and putative transmitter action.
- Neural control of shark rectal gland.
- Vasoactive intestinal peptide in the anterior pituitary is increased in hypoThyroidism.
- Thyrotropin-releasing Hormone precursor: characterization in rat brain.
- Immunolocalization of the thyrotropin-releasing Hormone proHormone in the rat central nervous system.
- Amyotrophic lateral sclerosis: thyrotropin-releasing Hormone and histidyl proline diketopiperazine in the spinal cord and cerebrospinal fluid.
- Identification and characterization of thyrotropin-releasing Hormone precursor peptides in rat brain.
Schools
University of Vermont College of Medicine
Beth Israel Hospital
Tufts New England Med Center
Conditions Treated
- Abnormal Thyroid
- Acromegaly and Gigantism
- Adrenal Incidentaloma
- Adrenal Insufficiency
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Doctors Specialties
- Endocrinology
Accepted Insurances
Awards
- America's Top Doctors
- Boston Magazine
- CMS Meaningful Use Stage 1 Certification
- Boston Herald
- Elected Member
- Super Doctor
Education
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Tufts Medical Center -
Beth Israel Deaconess Medical Center -
University of Vermont College of Medicine
Hospital
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Tufts Medical Center
Drug Facts
| NPI NUMBER | 1700824018 | |
| NPPES Provider LastName | LECHAN | |
| NPPES Provider FirstName | RONALD | |
| NPPES Provider ZIPCode | 02111 | |
| NPPES Provider State | MA | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 222.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1700824018 |
| Last Name Of The Provider | LECHAN |
| First Name Of The Provider | RONALD |
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