Deputy Director, Radiology and Imaging Sciences, NIH
Nuclear Medicine
Dr. Ronald D. Neumann, MD
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Ronald Neumann works in the field of Nuclear Medicine. He studied medicine at Yale University School of Medicine. Yale University School of Medicine is one of the top medical schools in the US. Yale University School of Medicine is ranked 7 in research and 57 in primary care medicine He has 1 awards "Whos Who in Medicine and Healthcare". Ronald Neumann is a published doctor and has 99 publications published. The lastest was: 'Phase I study of the pharmacokinetics of a radioimmunoconjugate, 90Y-T101, in patients with CD5-expressing leukemia and lymphoma.'
Publications
- G-Quadruplex Formation Between G-Rich PNA and Homologous Sequences in Oligonucleotides and Supercoiled Plasmid DNA.
- Changes in human pluripotent stem cell gene expression after genotoxic stress exposures.
- PPG Peptide Nucleic Acids that Promote DNA Guanine Quadruplexes.
- Perspective, the one most responsive to change.
- Human embryonic stem cell responses to ionizing radiation exposures: current state of knowledge and future challenges.
- Effect of 5-(125)Iiodo-2'-deoxyuridine uptake on the proliferation and pluripotency of human embryonic stem cells.
- Study of charge transport mechanisms in (125)I-induced DNA damage at various temperatures.
- Targeting DNA g-quadruplex structures with Peptide nucleic acids.
- Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region.
- Systems-related facts and consequences in assessing risk from low-level irradiation.
- Base damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-termini.
- Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: effect of exportins and DNA structure.
- Low-level ionizing radiation from noninvasive cardiac imaging: can we extrapolate estimated risks from epidemiologic data to the clinical setting?
- Low-dose cancer risk modeling must recognize up-regulation of protection.
- Assessing DNA structures with 125I radioprobing.
- Tracking radiation exposure from diagnostic imaging devices at the NIH.
- Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining.
- Radiation-induced bystander effects in cultured human stem cells.
- Duplex formation at the 5' end affects the quadruplex conformation of the human telomeric repeat overhang in sodium but not in potassium.
- Two principal considerations are needed after low doses of ionizing radiation.
- Phosphorylation of histone H2AX in radiation-induced micronuclei.
- Determination and analysis of site-specific 125I decay-induced DNA double-strand break end-group structures.
- An in vitro nonhomologous end-joining assay using linear duplex oligonucleotides.
- Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break.
- DNA damage produced by 125I-triplex-forming oligonucleotides as a measure of their successful delivery into cell nuclei.
- Characterization of complex apurinic/apyrimidinic-site clustering associated with an authentic site-specific radiation-induced DNA double-strand break.
- DNA uptake and repair enzyme access to transfected DNA is under reported by gene expression.
- A protocol for separation and isolation of small and/or large DNA fragments with high yield using CL4B Sepharose.
- Repair of radiation-induced DNA double-strand breaks is dependent upon radiation quality and the structural complexity of double-strand breaks.
- Iodine-125 radioprobing of E. coli RNA polymerase transcription elongation complexes.
- Repair of sequence-specific 125I-induced double-strand breaks by nonhomologous DNA end joining in mammalian cell-free extracts.
- Absorbed dose and the quantification of physical events at low-dose irradiation of tissue.
- Effects of low doses of ionizing radiation exposures on stress-responsive gene expression in human embryonic stem cells.
- Lessons Learned about Human Stem Cell Responses to Ionizing Radiation Exposures: A Long Road Still Ahead of Us.
- Survival of tumor cells in stem cell preparations and bone marrow of patients with high-risk or metastatic breast cancer after receiving dose-intensive or high-dose ch...
- Repeat unit sequence variation in minisatellites: a novel source of DNA polymorphism for studying variation and mutation by single molecule analysis.
- A malignant melanoma imaging agent: synthesis, characterization, in vitro binding and biodistribution of iodine-125-(2-piperidinylaminoethyl)4-iodobenzamide.
- Detection of pulmonary embolism in man with 111In-labeled autologous platelets.
- Neuropathy associated with acrodermatitis chronica atrophicans. Clinical and morphological features.
- Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism.
- Transferrin dependence of Ga (NO3)3 inhibition of growth in human-derived small cell lung cancer cells.
- Isolation of human simple repeat loci by hybridization selection.
- Recurrent 2-bp deletion in exon 10c of the NF1 gene in two cases of von Recklinghausen neurofibromatosis.
- Viruses as tools for studies on the molecular biology of mammalian cells.
- Cloned fragments of human adenovirus type-12 DNA.
- Minisatellite mutation frequency in human sperm following radiotherapy.
- Serum HER-2 extracellular domain: relationship with clinicobiological presentation and prognostic value before and after primary treatment in 701 breast cancer patients.
- A simple method for affinity purification of radiolabeled monoclonal antibodies.
- Integration of adenovirus type 2 DNA at a limited number of cellular sites in productively infected cells.
- Radiolabeled peptides and other ligands for receptors overexpressed in tumor cells for imaging neoplasms.
- Streptavidin distribution in metastatic tumors pretargeted with a biotinylated monoclonal antibody: theoretical and experimental pharmacokinetics.
- Radionuclide renography predicts functional changes in patients with renal artery involvement by Takayasu's arteritis.
- Amplification of human minisatellites by the polymerase chain reaction: towards DNA fingerprinting of single cells.
- STS for minisatellite 33.1 (D9S49): direct typing by PCR.
- Determination of the nucleotide sequence for the penton-base gene of human adenovirus type 5.
- The role of gallium-67 tumour scintigraphy in patients with small, non-cleaved cell lymphoma.
- Two-step targeting of experimental lung metastases with biotinylated antibody and radiolabeled streptavidin.
- Pulmonary and oxygen transport effects of intravenously administered endotoxin in normal humans.
- Correspondence Re: Timothy S. Loy, Paul L. Gelven, Dawn Mullins, and Alberto A. Diaz-Arias. Immunostaining for P-glycoprotein in the diagnosis of thyroid carcinomas. M...
- Two unusual cases of metastatic osteosarcoma detected by Tc-99m MDP bone scintigraphy.
- The U.S. Advisory Committee on Human Radiation Experiments.
- Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier.
- The role of positron emission tomography imaging in early assessment of the antitumor impact of biologics and cytotoxics.
- Iodine-131-metaiodobenzylguanidine scintigraphy in preoperative and postoperative evaluation of paragangliomas: comparison with CT and MRI.
- Pulmonary lymphangioleiomyomatosis: correlation of ventilation-perfusion scintigraphy, chest radiography, and CT with pulmonary function tests.
- Localization of Tc-99m MDP in cystosarcoma phyllodes.
- DNA methylation and viral gene expression in adenovirus-transformed and -infected cells.
- Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier.
- Gene radiotherapy; gene targeted versus targeted by gene product.
- Radiolabeled products in rat liver and serum after administration of antibody-amide-DTPA-indium-111.
- Evaluation of different methods for the detection of minimal residual disease in blood and bone marrow of patients with primary breast cancer: importance for clinical ...
- Phase I study of the pharmacokinetics of a radioimmunoconjugate, 90Y-T101, in patients with CD5-expressing leukemia and lymphoma.
- Measurement of local Mr 97,000 and 250,000 protein antigen concentration in sections of human melanoma tumor using in vitro quantitative autoradiography.
- Monoclonal antibodies for radioimmunoscintigraphy of breast cancer.
- In vitro complex formation and biodistribution of mouse antitumor monoclonal antibody in cancer patients.
- Collecting duct carcinoma of the kidney.
- Anti-murine antibody response to mouse monoclonal antibodies: clinical findings and implications.
- Comparison of bone marrow dosimetry and toxic effect of high dose 131I-labeled monoclonal antibodies administered to man.
- Quantitation of triple-helix formation using a photo-cross-linkable aryl azide/biotin/oligonucleotide conjugate.
- Development of DNA-based radiopharmaceuticals carrying Auger-electron emitters for antigene radiotherapy.
- Distribution of the 72-kd type IV collagenase in nonneoplastic and neoplastic thyroid tissue.
- Local distribution and concentration of intravenously injected 131I-9.2.27 monoclonal antibody in human malignant melanoma.
- Scintigraphic findings and follow up in Erdheim-Chester disease.
- Parathyroid imaging by Tc/Tl scintigraphy.
- Value of gross cystic disease fluid protein-15 in distinguishing metastatic breast carcinomas among poorly differentiated neoplasms involving the ovary.
- Positive gallium-67 citrate scintigraphy in Wiskott-Aldrich syndrome with malignant lymphoma.
- P-glycoprotein expression is increased in human secretory and gestational endometrium.
- Immunohistochemical detection of P-glycoprotein in endometrial adenocarcinoma.
- Ultrastructural histology correlates with results of thallium-201/technetium-99m parathyroid subtraction scintigraphy.
- Effect of metabolism on retention of indium-111-labeled monoclonal antibody in liver and blood.
- Application of high affinity binding concept to radiolabel avidin with Tc-99m labeled biotin and the effect of pI on biodistribution.
- Targeting of transferrin receptors in nude mice bearing A431 and LS174T xenografts with [18F]holo-transferrin: permeability and receptor dependence.
- Monitoring responses to antiangiogenic agents using noninvasive imaging tests.
- Differential cellular catabolism of 111In, 90Y and 125I radiolabeled T101 anti-CD5 monoclonal antibody.
- Kinetic analysis of muscarinic receptors in human brain and salivary gland in vivo.
- What is new in nuclear medicine imaging?
- Radiotoxicity of iodine-125-labeled oligodeoxyribonucleotides in mammalian cells.
- Genome-wide gene expression changes in normal human fibroblasts in response to low-LET gamma-radiation and high-LET-like 125IUdR exposures.
Schools
Yale University
Doctors Specialties
- Nuclear Medicine
Accepted Insurances
Awards
- Whos Who in Medicine and Healthcare
Education
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Yale University School of Medicine
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