Physician
Internal Medicine
Dr. Roger J. Pomerantz, MD
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Doctor Roger J. Pomerantz, MD is an expert in the field of Internal Medicine. Roger J. Pomerantz, MD is a published doctor as well. He has 71 publications published. The latest was: Generation of retroviral particles for the spleen necrosis virus (SNV)-based vector system and their use in transduction of various cell types.
Publications
- Generation of retroviral particles for the spleen necrosis virus (SNV)-based vector system and their use in transduction of various cell types.
- The challenge of finding a cure for HIV infection.
- Hide-and-seek: the challenge of viral persistence in HIV-1 infection.
- Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rh...
- Cholesterol-depleting statin drugs protect postmitotically differentiated human neurons against ethanol- and human immunodeficiency virus type 1-induced oxidative stre...
- HIV-1 Vpr potently induces programmed cell death in the CNS in vivo.
- Rabies virus glycoprotein as a carrier for anthrax protective antigen.
- Inhibition of endogenous reverse transcription of human and nonhuman primate lentiviruses: potential for development of lentivirucides.
- siRNA targeting vaccinia virus double-stranded RNA binding protein [E3L] exerts potent antiviral effects.
- Attenuation of HIV-1 infection by other microbial agents.
- Seminal reservoirs during an HIV type 1 eradication trial.
- HIV type 1 cervicovaginal reservoirs in the era of HAART.
- Exogenous IL-7 induces Fas-mediated human neuronal apoptosis: potential effects during human immunodeficiency virus type 1 infection.
- Molecular interactions of human immunodeficiency virus type 1 with primary human oral keratinocytes.
- The RNA helicase DDX1 is involved in restricted HIV-1 Rev function in human astrocytes.
- Current status of gene therapy strategies to treat HIV/AIDS.
- Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines.
- Human Immunodeficiency virus type 1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells via the activation of caspases.
- Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.
- Spleen necrosis virus-based vector delivery of anti-HIV-1 genes potently protects human hematopoietic cells from HIV-1 infection.
- Caffeine inhibits human immunodeficiency virus type 1 transduction of nondividing cells.
- IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.
- Antiretroviral therapy in the developing world.
- T-Cells and excitotoxicity: HIV-1 and other neurodegenerative disorders.
- A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev.
- The perlecan heparan sulfate proteoglycan mediates cellular uptake of HIV-1 Tat through a pathway responsible for biological activity.
- Antiviral effects of human immunodeficiency virus type 1-specific small interfering RNAs against targets conserved in select neurotropic viral strains.
- Immunogenicity study of glycoprotein-deficient rabies virus expressing simian/human immunodeficiency virus SHIV89.6P envelope in a rhesus macaque.
- Cross-packaging of human immunodeficiency virus type 1 vector RNA by spleen necrosis virus proteins: construction of a new generation of spleen necrosis virus-derived ...
- HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy.
- Expression of latent HAART-persistent HIV type 1 induced by novel cellular activating agents.
- Spliced spleen necrosis virus vector RNA is not encapsidated: implications for retroviral replication and vector design.
- Effects of HIV-1 Vpr on neuroinvasion and neuropathogenesis.
- HIV and GB virus C--can two viruses be better than one?
- HIV-1 infection and genomics: sorting out the complexity.
- The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity.
- Covalently linked human immunodeficiency virus type 1 gp120/gp41 is stably anchored in rhabdovirus particles and exposes critical neutralizing epitopes.
- Peripheral blood Dendritic cells are not a major reservoir for HIV type 1 in infected individuals on virally suppressive HAART.
- Treatment of Mycobacterium avium complex immune reconstitution disease in HIV-1-infected individuals.
- Human immunodeficiency virus type 1 enters primary human brain microvascular endothelial cells by a mechanism involving cell surface proteoglycans independent of lipid...
- Rev binds specifically to a purine loop in the SL1 region of the HIV-1 leader RNA.
- Genotypic alteration of HAART-persistent HIV-1 reservoirs in vivo.
- Cell-type-specific gene delivery into neuronal cells in vitro and in vivo.
- Structural and functional study of the apelin-13 peptide, an endogenous ligand of the HIV-1 coreceptor, APJ.
- Inhibition of HIV-1 in the central nervous system by IFN-alpha2 delivered by an SV40 vector.
- Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1.
- Slower progression of HIV-1 infection in persons with GB virus C co-infection correlates with an intact T-helper 1 cytokine profile.
- Twenty years of therapy for HIV-1 infection.
- Cell-cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ.
- Reservoirs, sanctuaries, and residual disease: the hiding spots of HIV-1.
- Immune reconstitution syndrome in AIDS. Interview by Vicki Glaser.
- Potent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins.
- In a subset of subjects on highly active antiretroviral therapy, human immunodeficiency virus type 1 RNA in plasma decays from 50 to <5 copies per milliliter, with a h...
- Replication of lentiviruses.
- Second-generation rabies virus-based vaccine vectors expressing human immunodeficiency virus type 1 gag have greatly reduced pathogenicity but are highly immunogenic.
- Ethanol strongly potentiates apoptosis induced by HIV-1 proteins in primary human brain microvascular endothelial cells.
- Approaching eradication of highly active antiretroviral therapy-persistent human immunodeficiency virus type 1 reservoirs with immune activation therapy.
- Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretrovir...
- New methods for the detection of HIV.
- HIV-1 reservoirs.
- RNA interference meets HIV-1: will silence be golden?
- A trans-dominant negative HIV type 1 Rev with intact domains of NLS/NOS and NES.
- Primary isolated human brain microvascular endothelial cells express diverse HIV/SIV-associated chemokine coreceptors and DC-SIGN and L-SIGN.
- Gene therapy using a simian virus 40-derived vector inhibits the development of in vivo human immunodeficiency virus type 1 infection of severe combined immunodeficien...
- Lentiviral expression of HIV-1 Vpr induces apoptosis in human neurons.
- Live and killed rhabdovirus-based vectors as potential hepatitis C vaccines.
- Reservoirs of human immunodeficiency virus type 1: the main obstacles to viral eradication.
- Rhabdovirus-based vectors with human immunodeficiency virus type 1 (HIV-1) envelopes display HIV-1-like tropism and target human dendritic cells.
- Combination genetic therapy to inhibit HIV-1.
- Central nervous system infections in individuals with HIV-1 infection.
Schools
Johns Hopkins University School of Medicine
Doctors Specialties
- Infectious Disease Medicine
- Internal Medicine
Accepted Insurances
Education
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Massachusetts General Hospital
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