Physician
Allergy & Immunology
Dr. Robert Yarchoan, MD
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Doctor Robert Yarchoan, MD is an expert in the field of Allergy & Immunology. He received awards:"Elected Member" and "Whos Who in Medicine and Healthcare". Doctor Robert Yarchoan, MD is a published doctor as well. He has 72 publications published. The latest was: Pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS and related disorders.
Publications
- Rituximab plus liposomal doxorubicin in HIV-infected patients with KSHV-associated multicentric Castleman disease.
- A sensitive and robust HPLC assay with fluorescence detection for the quantification of pomalidomide in human plasma for pharmacokinetic analyses.
- Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome.
- Activation of virus uptake through induction of macropinocytosis with a novel polymerizing peptide.
- Human and viral interleukin-6 and other cytokines in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.
- Bone Marrow Findings in HIV-Positive Patients With Kaposi Sarcoma Herpesvirus-Associated Multicentric Castleman Disease.
- A20/TNFAIP3 inhibits NF-?B activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.
- KSHV microRNAs target two components of the TLR/IL-1R signaling cascade, IRAK1 and MYD88, to reduce inflammatory cytokine expression.
- Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors against the Initial Autocleavage in Gag-Pol Polyprotein Processing.
- Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.
- Evaluation of non-invasive multispectral imaging as a tool for measuring the effect of systemic therapy in kaposi sarcoma.
- Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients.
- Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induction by hypoxia and hypoxia-inducible factors.
- Kaposi''s sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation.
- High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy.
- Cancer Burden in the HIV-Infected Population in the United States.
- IL-15 ex vivo overcomes CD4+ T cell deficiency for the induction of human antigen-specific CD8+ T cell responses.
- Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
- The initial step in human immunodeficiency virus type 1 GagProPol processing can be regulated by reversible oxidation.
- Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib.
- An interleukin-6-related systemic inflammatory syndrome in patients co-infected with Kaposi sarcoma-associated herpesvirus and HIV but without Multicentric Castleman d...
- Characterization of immune responses to capsid protein p24 of human immunodeficiency virus type 1 and implications for detection.
- Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion...
- Characterization of the activation of protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1) by hypoxia inducible factor-2 alpha.
- Detection of antibodies to Kaposi''s sarcoma-associated herpesvirus: a new approach using K8.1 ELISA and a newly developed recombinant LANA ELISA.
- The role of tumor histogenesis, FDG-PET, and short-course EPOCH with dose-dense rituximab (SC-EPOCH-RR) in HIV-associated diffuse large B-cell lymphoma.
- Identification of a potential pharmacological sanctuary for HIV type 1 in a fraction of CD4(+) primary cells.
- Radiotherapy for patients with the human immunodeficiency virus: are special precautions necessary?
- Analysis and characterization of dimerization inhibition of a multi-drug-resistant human immunodeficiency virus type 1 protease using a novel size-exclusion chromatogr...
- A splenic marginal zone-like peripheral blood CD27+B220- B cell population is preferentially depleted in HIV type 1-infected individuals.
- Treatment of AIDS-related Kaposi's sarcoma with interleukin-12: rationale and preliminary evidence of clinical activity.
- Using noninvasive multispectral imaging to quantitatively assess tissue vasculature.
- Using quantitative imaging techniques to assess vascularity in AIDS-related Kaposi's sarcoma.
- Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma.
- Nanoparticle-Based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen.
- Hypoxia enhances the phosphorylation and cytotoxicity of ganciclovir and zidovudine in Kaposi's sarcoma-associated herpesvirus infected cells.
- Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization.
- Immunologic, virologic, and neuropsychologic responses in human immunodeficiency virus-infected children receiving their first highly active antiretroviral therapy reg...
- Noninvasive Multimodality Imaging Techniques to Assess Kaposi's Sarcoma.
- Noninvasive infrared imaging for quantitative assessment of tumor vasculature and response to therapy.
- Conservation of virally encoded microRNAs in Kaposi sarcoma--associated herpesvirus in primary effusion lymphoma cell lines and in patients with Kaposi sarcoma or mult...
- Key role for a viral lytic gene in Kaposi's sarcoma.
- Poor specific T cell responses to human herpesvirus 8: A key to unleashing Kaposi sarcoma?
- Possible therapeutic vaccine strategy against human immunodeficiency virus escape from reverse transcriptase inhibitors studied in HLA-A2 transgenic mice.
- Acquired immunodeficiency syndrome-related malignancies in the era of highly active antiretroviral therapy.
- Genetic organization and hypoxic activation of the Kaposi's sarcoma-associated herpesvirus ORF34-37 gene cluster.
- Inhibition of HIV-1 replication by a peptide dimerization inhibitor of HIV-1 protease.
- Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.
- Preferential inhibition of the magnesium-dependent strand transfer reaction of HIV-1 integrase by alpha-hydroxytropolones.
- Therapy insight: AIDS-related malignancies--the influence of antiviral therapy on pathogenesis and management.
- Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells.
- Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation.
- Natural history of lipid abnormalities and fat redistribution among human immunodeficiency virus-infected children receiving long-term, protease inhibitor-containing, ...
- The use of antiretroviral therapy in patients undergoing treatment for HIV-related neoplastic disease.
- Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity.
- Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo.
- An in vivo replication-important function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection.
- Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis.
- Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains hypoxia response elements: relevance to lytic induction by hypoxia.
- Treatment of gammaherpesvirus-related neoplastic disorders in the immunosuppressed host.
- Highly effective treatment of acquired immunodeficiency syndrome-related lymphoma with dose-adjusted EPOCH: impact of antiretroviral therapy suspension and tumor biology.
- Infection of mesothelial cells with human herpes virus 8 in human immunodeficiency virus-infected patients with Kaposi's sarcoma, Castleman's disease, and recurrent pl...
- Reversible oxidative modification as a mechanism for regulating retroviral protease dimerization and activation.
- A pilot study of cidofovir in patients with kaposi sarcoma.
- Development of Kaposi's sarcoma at the site of a biopsy.
- Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy.
- Reversible oxidation of HIV-2 protease.
- Oxidative modifications of kynostatin-272, a potent human immunodeficiency virus type 1 protease inhibitor: potential mechanism for altered activity in monocytes/macro...
- Minimal reactivation of Kaposi's sarcoma-associated herpesvirus by corticosteroids in latently infected B cell lines.
- Pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS and related disorders.
- Cancer prevention in HIV-infected populations.
Schools
Perelman School of Medicine University of Pennsylvania
Doctors Specialties
- Internal Medicine
- Allergy
- Immunology
Accepted Insurances
Awards
- Elected Member
- Whos Who in Medicine and Healthcare
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