Physician
Pulmonology
Dr. Robert M. Strieter, MD
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Robert Strieter practices Pulmonology. Robert Strieter is a published doctor. He published 101 publications, including: 'CXCR4, but not CXCR7, discriminates metastatic behavior in non-small cell lung cancer cells.'
Publications
- CXCR4, but not CXCR7, discriminates metastatic behavior in non-small cell lung cancer cells.
- Dose-dependent Effect of Statin Therapy on Circulating CXCL12 Levels in Patients with Hyperlipidemia.
- Myeloid suppressor cell depletion augments antitumor activity in lung cancer.
- Fibrocytes and the pathogenesis of diffuse parenchymal lung disease.
- Type I immune response cytokine-chemokine cascade is associated with Pulmonary arterial hypertension.
- Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors.
- Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis.
- Neutrophil Mobilization from the Bone Marrow during Polymicrobial Sepsis Is Dependent on CXCL12 Signaling.
- Role of CXCR3 Ligands in IL-7/IL-7R{alpha}-Fc-Mediated Antitumor Activity in Lung Cancer.
- Chemokines as mediators of tumor angiogenesis and neovascularization.
- Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer.
- Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3.
- Plasma chemokine levels are associated with the presence and extent of angiographic coronary collaterals in chronic ischemic heart disease.
- Role of LTB(4) in the pathogenesis of elastase-induced murine Pulmonary emphysema.
- Neutropenia enhances lung dendritic cell recruitment in response to Aspergillus via a cytokine-to-chemokine amplification loop.
- Interferons induce CXCR3-cognate chemokine production by human metastatic melanoma.
- V(alpha)14iNKT cells promote liver pathology during adenovirus infection by inducing CCL5 production: implications for gene therapy.
- An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells.
- Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.
- IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury.
- CXC chemokines in cancer angiogenesis and metastases.
- Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection.
- Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma.
- The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of Pulmonary fibrosis.
- New mechanisms of Pulmonary fibrosis.
- CXC-chemokine/CXCR2 biological axis promotes angiogenesis in vitro and in vivo in pancreatic cancer.
- NKT cells mediate Pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines.
- IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer.
- Therapeutic effect of blocking CXCR2 on neutrophil recruitment and dextran sodium sulfate-induced colitis.
- Circulating fibrocytes are an indicator of poor prognosis in idiopathic Pulmonary fibrosis.
- Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli.
- Early NK cell-derived IFN-{gamma} is essential to host defense in neutropenic invasive aspergillosis.
- CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.
- The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting Pulmonary fibrosis.
- Chemokines as mediators of neovascularization.
- GammadeltaT cells initiate acute inflammation and injury in adenovirus-infected liver via cytokine-chemokine cross talk.
- Out of the shadows: CXC chemokines in promoting aberrant lung cancer angiogenesis.
- Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.
- Identification of secreted proteins that mediate cell-cell interactions in an in vitro model of the lung cancer microenvironment.
- Depletion of beta-arrestin-2 promotes tumor growth and angiogenesis in a murine model of lung cancer.
- What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis.
- The chemokine receptor CXCR3 is an independent prognostic factor in patients with localized clear cell renal cell carcinoma.
- Bcl-2 orchestrates a cross-talk between endothelial and tumor cells that promotes tumor growth.
- Opposing roles of murine duffy antigen receptor for chemokine and murine CXC chemokine receptor-2 receptors in murine melanoma tumor growth.
- Fibrocytes in lung disease.
- Differentiation of human circulating fibrocytes as mediated by transforming growth factor-beta and peroxisome proliferator-activated receptor gamma.
- Keratinocyte growth factor improves repair in the injured tracheal epithelium.
- Platelet factor-4 variant chemokine CXCL4L1 inhibits melanoma and lung carcinoma growth and metastasis by preventing angiogenesis.
- Expression of CXCR3 on mononuclear cells and CXCR3 ligands in patients with metastatic renal cell carcinoma in response to Systemic IL-2 therapy.
- The role of CXC chemokines in Pulmonary fibrosis.
- Circulating peripheral blood fibrocytes in human fibrotic interstitial lung disease.
- Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB.
- Stem cells and chronic lung disease.
- IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.
- Inflammation and angiogenesis in fibrotic lung disease.
- Mycoplasma fermentans and TNF-beta interact to amplify immune-modulating cytokines in human lung fibroblasts.
- The role of cytokines during the pathogenesis of ventilator-associated and ventilator-induced lung injury.
- CXCR3+CD4+ T cells mediate innate immune function in the pathophysiology of liver ischemia/reperfusion injury.
- High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
- Matrix metalloproteinases and matrix metalloproteinase inhibitors in acute lung injury.
- IntraPulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
- Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury.
- CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis.
- Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor im...
- Characterization of human fibrocytes as circulating adipocyte progenitors and the formation of human adipose tissue in SCID mice.
- CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury.
- CXCR2/CXCR2 ligand biological axis impairs alveologenesis during dsRNA-induced lung inflammation in mice.
- Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 beta-induced neovascularization and tumor growth.
- Pathogenesis and natural history of usual interstitial pneumonia: the whole story or the last chapter of a long novel.
- The role of CXCR2/CXCR2 ligand biological axis in renal cell carcinoma.
- CD14 deficiency leads to increased MIP-2 production, CXCR2 expression, neutrophil transmigration, and early death in pneumococcal infection.
- Masters of angiogenesis.
- IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
- Inhibition of polymorphonuclear leukocyte-mediated graft damage synergizes with short-term costimulatory blockade to prevent cardiac allograft rejection.
- Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses.
- Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines.
- Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinas...
- CXCR2 is critical for dsRNA-induced lung injury: relevance to viral lung infection.
- Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome.
- CXCL11 attenuates bleomycin-induced Pulmonary fibrosis via inhibition of vascular remodeling.
- Pulmonary fibrosis.
- Mechanisms and mediators of Pulmonary fibrosis.
- CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer.
- Identification and partial characterization of a variant of human CXCR3 generated by posttranscriptional exon skipping.
- BRAK/CXCL14 is a potent inhibitor of angiogenesis and a chemotactic factor for immature dendritic cells.
- Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis.
- Increased bronchoalveolar lavage human beta-defensin type 2 in bronchiolitis obliterans syndrome after lung transplantation.
- The role of the Th2 CC chemokine ligand CCL17 in Pulmonary fibrosis.
- Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis.
- Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmona...
- Innate immunity dictates cytokine polarization relevant to the development of Pulmonary fibrosis.
- Chemokine monokine induced by IFN-gamma/CXC chemokine ligand 9 stimulates T lymphocyte proliferation and effector cytokine production.
- CXC chemokines in angiogenesis of cancer.
- The chemokine receptor, CXCR2, mediates the tumorigenic effects of ELR+ CXC chemokines.
- Intratumoral administration of dendritic cells overexpressing CCL21 generates Systemic antitumor responses and confers tumor immunity.
- CXCR2 is critical to hyperoxia-induced lung injury.
- Association between Pulmonary fibrosis and coronary artery disease.
- Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer.
- Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer.
- Contrasting roles for CXCR2 during experimental colitis.
Schools
Michigan State University
St Joseph Mercy Hospital
University Mich Med Center
Conditions Treated
- Pulmonary Hypertension
- Sarcoidosis
- Systemic Sclerosis
Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
Education
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University of Michigan Hospitals and Health Centers -
St Joseph Mercy Livingston Hospital -
Michigan State University College of Human Medicine
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