Physician
Family Medicine
Dr. Robert A. McKnight Jr., MD
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Robert A. McKnight Jr., MD is an expert in the field of Family Medicine. He went to medical school at University of Arkansas for Medical Sciences College of Medicine. University of Arkansas for Medical Sciences College of Medicine is ranked 83/35 in Research/PrimaryCare. Robert A. McKnight Jr., MD is a published MD as well. He has 52 publications published. The latest was: Severe position effects imposed on a 1 kb mouse whey acidic protein gene promoter are overcome by heterologous matrix attachment regions. Robert A. McKnight Jr., MD is registered with Medicare.
Publications
- Intrauterine growth restriction perturbs nucleosome depletion at a growth hormone responsive element in the mouse IGF-1 gene.
- Intrauterine growth restriction disrupts developmental epigenetics around distal growth hormone response elements on the rat hepatic IGF-1 gene.
- Combination of intrauterine growth restriction and a high-fat diet impairs cholesterol elimination in rats.
- Essential nutrient supplementation prevents heritable metabolic disease in multigenerational intrauterine growth-restricted rats.
- Fetal growth restriction alters hippocampal 17-beta estradiol and estrogen receptor alpha levels in the newborn male rat.
- Intrauterine growth restriction transiently delays alveolar formation and disrupts retinoic acid receptor expression in the lung of female rat pups.
- Novel thromboxane A2 analog-induced IUGR mouse model.
- Intrauterine Growth Restriction Affects Hippocampal Dual Specificity Phosphatase 5 Gene Expression and Epigenetic Characteristics.
- IUGR decreases elastin mRNA expression in the developing rat lung and alters elastin content and lung compliance in the mature rat lung.
- IUGR Alters T-Lymphocyte Cell Number and DUSP1 Levels in the Thymus of Newborn and Juvenile Rats.
- IUGR differentially alters MeCP2 expression and H3K9Me3 of the PPARγ gene in male and female rat lungs during alveolarization.
- Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth.
- Intrauterine growth retardation affects expression and epigenetic characteristics of the rat hippocampal glucocorticoid receptor gene.
- Fetal growth restriction alters transcription factor binding and epigenetic mechanisms of renal 11beta-hydroxysteroid dehydrogenase type 2 in a sex-specific manner.
- Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene.
- Intrauterine growth restriction due to uteroplacental insufficiency decreased white matter and altered NMDAR subunit composition in juvenile rat hippocampi.
- Nasal ventilation alters mesenchymal cell turnover and improves alveolarization in preterm lambs.
- Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction.
- Uteroplacental insufficiency alters nephrogenesis and downregulates cyclooxygenase-2 expression in a model of IUGR with adult-onset hypertension.
- Growth retardation alters the epigenetic characteristics of hepatic dual specificity phosphatase 5.
- Uteroplacental insufficiency increases p53 phosphorylation without triggering the p53-MDM2 functional circuit response in the IUGR rat kidney.
- Uteroplacental insufficiency alters hepatic expression, phosphorylation, and activity of the glucocorticoid receptor in fetal IUGR rats.
- Nonresponsiveness of cerebral p53-MDM2 functional circuit in newborn rat pups rendered IUGR via uteroplacental insufficiency.
- Uteroplacental insufficiency induces site-specific changes in histone H3 covalent modifications and affects DNA-histone H3 positioning in day 0 IUGR rat liver.
- Glucose transporter GLUT8 translocation in neurons is not insulin responsive.
- Aberrant insulin-induced GLUT4 translocation predicts glucose intolerance in the offspring of a diabetic mother.
- Production of the mouse whey acidic protein in transgenic pigs during lactation.
- Severe position effects imposed on a 1 kb mouse whey acidic protein gene promoter are overcome by heterologous matrix attachment regions.
- High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine.
- Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population.
- Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation.
- Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice.
- The whey acidic protein.
- Expression of genomic and cDNA transgenes after co-integration in transgenic mice.
- Regulation of human protein C gene expression by the mouse WAP promoter.
- An Ets site in the whey acidic protein gene promoter mediates transcriptional activation in the mammary gland of pregnant mice but is dispensable during lactation.
- GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst.
- Developmental regulation of genes mediating murine brain glucose uptake.
- Epigenetics and fetal adaptation to perinatal events: diversity through fidelity.
- Effect of development and hypoxic-ischemia upon rabbit brain glucose transporter expression.
- Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats.
- Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs.
- Gestational programming of offspring obesity: a potential contributor to Alzheimer''s disease.
- Uteroplacental insufficiency affects kidney VEGF expression in a model of IUGR with compensatory glomerular hypertrophy and hypertension.
- Intrauterine growth restriction disturbs mediators of placental protein turnover.
- Placental variability in methylation reflects maternal and fetal pathogenesis.
- Intrauterine growth restriction, neural microRNA expression and hypertension in the mouse.
- Stem cell DNA methylation: a consequence of intrauterine growth restriction.
- Mechanical-tactile stimulation (MTS) during neonatal stress prevents hyperinsulinemia despite stress-induced adiposity in weanling rat pups.
- IUGR decreases PPARγ and SETD8 Expression in neonatal rat lung and these effects are ameliorated by maternal DHA supplementation.
- Uteroplacental insufficiency increases visceral adiposity and visceral adipose PPARgamma2 expression in male rat offspring prior to the onset of obesity.
Schools
Univ Of Ar Coll Of Med
University South Ala
Doctors Specialties
- Family Medicine
Accepted Insurances
- Choice Plus POS II
- Assurant Health
- Blue Card PPO
- Dental Blue 100/200/300
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Commercial Insurance Company
- First Health (Coventry Health Care) PPO
- Choice Care PPO
- Medicare MCR
- POMCO Group
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Education
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University of South Alabama -
University of Arkansas for Medical Sciences College of Medicine
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