Professor of Medicine
Endocrinology
Dr. Richard J. Auchus, MD
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Richard Auchus is an expert in the field of Endocrinology. He went to medical school at Washington University School of Medicine in St. Louis. He received 1 awards: "CMS Meaningful Use Stage 1 Certification". Richard J. Auchus, MD is also published. He has 98 publications published. The lastest publication: "Mifepristone Improves Octreotide Efficacy in Resistant Ectopic Cushing's Syndrome.' He accepts Medicare payments and is registered with Medicare.gov.
Publications
- Adrenocortical carcinoma in a 17th-century girl.
- Cortisol response to acute stress in asthma: Moderation by depressive mood.
- The Metabolism, Analysis, and Targeting of Steroid Hormones in Breast and Prostate Cancer.
- Impaired 17,20-lyase activity in male mice lacking cytochrome b5 in Leydig cells.
- Adrenal-derived 11-Oxygenated 19-Carbon Steroids are the Dominant Androgens in Classic 21-Hydroxylase Deficiency.
- Exhaled Nitric Oxide Decreases during Academic Examination Stress in Asthma.
- Rapid kinetic methods to dissect steroidogenic cytochrome P450 reaction mechanisms.
- Catecholamine-resistant hypotension and myocardial performance following patent ductus arteriosus ligation.
- Genetics of Primary Aldosteronism.
- Genetic Forms of Adrenal Insufficiency.
- The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1).
- Ectopic Prolactin Secretion From a Perivascular Epithelioid Cell Tumor (PEComa).
- Epoxidation Activities of Human Cytochromes P450c17 and P450c21.
- Urine Free Cortisol in the Diagnosis of Cushing's Syndrome: Is it worth doing and, if so, how?
- Use of Prednisone With Abiraterone Acetate in Metastatic Castration-Resistant Prostate Cancer.
- Adrenal androgens and androgen precursors-definition, synthesis, regulation and physiologic actions.
- Catalytically Relevant Electrostatic Interactions of Cytochrome P450c17 (CYP17A1) and Cytochrome b5.
- Androstenedione is the preferred androgen source in hormone refractory prostate cancer-letter.
- Steroid assays and endocrinology: best practices for basic scientists.
- The contribution of serine 194 phosphorylation to steroidogenic acute regulatory protein function.
- Abiraterone Acetate to Lower Androgens in Women With Classic 21-Hydroxylase Deficiency.
- The clinical phenotype of SDHC-associated hereditary paraganglioma Syndrome (PGL3).
- Hypotension following Patent Ductus Arteriosus Ligation: The Role of Adrenal Hormones.
- A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone.
- Fertility in patients With genetic deficiencies of cytochrome P450c17 (CYP17A1): combined 17-hydroxylase/17,20-lyase deficiency and isolated 17,20-lyase deficiency.
- Two surfaces of cytochrome b5 With major and minor contributions to CYP3A4-catalyzed steroid and nifedipine oxygenation chemistries.
- Prostaglandins Are Essential for Cervical Ripening in LPS-Mediated Preterm Birth But Not Term or Antiprogestin-Driven Preterm Ripening.
- A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer.
- Cortisol Response to Operative Stress With Anesthesia in Healthy Children.
- Approach to the patient: the adult with congenital Adrenal hyperplasia.
- Academic exam stress and depressive mood are associated With reductions in exhaled nitric oxide in healthy individuals.
- A randomized, placebo-controlled proof-of-concept, crossover trial of phenytoin for hydrocortisone-induced declarative memory changes.
- The action of cytochrome b(5) on CYP2E1 and CYP2C19 activities requires anionic residues D58 and D65.
- Introduction to the 2012 Keith L. Parker Memorial Lecturer: Walter L. Miller, MD.
- Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development.
- Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: a rationale for increasing drug exposure in castration-resistant prostate cancer.
- Spironolactone Prevents Chlorthalidone-Induced Sympathetic Activation and Insulin Resistance in Hypertensive Patients.
- Low testosterone levels and increased inflammatory markers in patients With cancer and relationship With cachexia.
- Effects of psychosocial stress on the pattern of salivary protein release.
- Clinical and Biochemical Consequences of CYP17A1 Inhibition With Abiraterone Given With and Without Exogenous Glucocorticoids in Castrate Men With Advanced Prostate Ca...
- Comprehensive 2-dimensional gas chromatography fast quadrupole mass spectrometry (GC????????GC-qMS) for urinary steroid profiling: Mass spectral characteristics With c...
- Steroid profiling by gas chromatography-mass spectrometry and high performance liquid chromatography-mass spectrometry for Adrenal diseases.
- Phenotypic variation in a Chinese family With 46,XY and 46,XX 17?-hydroxylase deficiency.
- Synthesis of halogenated pregnanes, mechanistic probes of steroid hydroxylases CYP17A1 and CYP21A2.
- Detection of synthetic testosterone use by novel comprehensive two-dimensional gas chromatography combustion-isotope ratio mass spectrometry.
- Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer.
- Exercise Training Versus Propranolol in the Treatment of the Postural Orthostatic Tachycardia Syndrome.
- Why human cytochrome P450c21 is a progesterone 21-hydroxylase.
- Primary aldosteronism and a Texas two-step.
- Clinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: a new Syndrome.
- The molecular biology, biochemistry, and physiology of human steroidogenesis and its Disorders.
- CYP17A1 intron mutation causing cryptic splicing in 17?-hydroxylase deficiency.
- Acute Stress-induced Increases in Exhaled Nitric Oxide in Asthma and Their Association With Endogenous Cortisol.
- Reversible sympathetic overactivity in hypertensive patients With primary aldosteronism.
- 3beta-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer.
- Menstrual cycle affects renal-Adrenal and hemodynamic responses during prolonged standing in the postural orthostatic tachycardia syndrome.
- Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases Types 1 and 2 in HEK-293 cells.
- Venus and the heart: endocrine influences on cardiovascular health in women.
- Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
- Synthesis and activity of dafachronic acid ligands for the C. elegans DAF-12 nuclear hormone receptor.
- Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients.
- Non-traditional metabolic pathways of Adrenal steroids.
- Rapid cortisol assays improve the success rate of Adrenal vein sampling for primary aldosteronism.
- Androstenedione up-regulation of endometrial aromatase expression via local conversion to estrogen: potential relevance to the pathogenesis of endometriosis.
- HyperThyroidism-associated coronary vasospasm with myocardial infarction and subsequent euThyroid angina.
- "Subclinical Cushing's syndrome" is not subclinical: improvement after Adrenalectomy in 9 patients.
- Basic concepts and recent developments in human steroid hormone biosynthesis.
- Will the lessons from primary aldosteronism change the treatment of hypertension and left ventricular hypertrophy?
- Measurement of 18-hydroxycorticosterone during Adrenal vein sampling for primary aldosteronism.
- Variable phenotypes associated with aromatase (CYP19) Insufficiency in humans.
- Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement.
- Alpha2cDel322-325 and beta1Arg389 adrenergic polymorphisms are not associated With reduced left ventricular ejection fraction or increased left ventricular volume.
- Associations among androgens, estrogens, and natriuretic peptides in young women: observations from the Dallas Heart Study.
- A homozygous ZMPSTE24 null mutation in combination with a heterozygous mutation in the LMNA gene causes Hutchinson-Gilford progeria Syndrome (HGPS): insights into the ...
- Do allelic variants in alpha2A and alpha2C adrenergic receptors predispose to hypertension in blacks?
- Role of the alternate pathway of dihydrotestosterone formation in virilization of the Wolffian ducts of the tammar wallaby, Macropus eugenii.
- Arginine 276 controls the directional preference of AKR1C9 (rat liver 3alpha-hydroxysteroid dehydrogenase) in human embryonic kidney 293 cells.
- Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans.
- Epithelial sodium channel allele T594M is not associated With blood pressure or blood pressure response to amiloride.
- Human cytochrome b5 requires residues E48 and E49 to stimulate the 17,20-lyase activity of cytochrome P450c17.
- Miscellaneous endocrine causes of hypertension.
- Overview of dehydroepiandrosterone biosynthesis.
- The rise in Adrenal androgen biosynthesis: adrenarche.
- The backdoor pathway to dihydrotestosterone.
- Human 17beta-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional Metabolism, in HEK-293 cells.
- Two intronic mutations cause 17-hydroxylase deficiency by disrupting splice acceptor sites: direct demonstration of aberrant splicing and absent enzyme activity by exp...
- CYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding.
- 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17.
- The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
- 5alpha-androstane-3alpha,17beta-diol is formed in tammar wallaby pouch young testes by a pathway involving 5alpha-pregnane-3alpha,17alpha-diol-20-one as a key intermed...
- The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.
- Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species.
- Towards a unifying mechanism for CYP17 mutations that cause isolated 17,20-lyase deficiency.
- Gene mutations that promote Adrenal aldosterone production, sodium retention, and hypertension.
- Increases in exhaled nitric oxide after acute stress: association With measures of negative affect and depressive mood.
- Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).
- Mifepristone Improves Octreotide Efficacy in Resistant Ectopic Cushing's Syndrome.
Schools
Washington Center School of Medicine
University Ia Hosps Clins
Wilford Hall Usaf Mc University Tex San Antonio
Procedures Preformed
- Contraceptive Management
Conditions Treated
- Abnormal Thyroid
- Acromegaly and Gigantism
- Adrenal Incidentaloma
- Adrenal Insufficiency
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Doctors Specialties
- Endocrinology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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San Antonio Uniformed Services Health Education Consortium -
University of Iowa Hospitals and Clinics -
Washington University School of Medicine in St. Louis
Hospital
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University of Michigan Hospitals and Health Centers
Drug Facts
| NPI NUMBER | 1083670251 | |
| NPPES Provider LastName | AUCHUS | |
| NPPES Provider FirstName | RICHARD | |
| NPPES Provider ZIPCode | 48105 | |
| NPPES Provider State | MI | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 86.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1083670251 |
| Last Name Of The Provider | AUCHUS |
| First Name Of The Provider | RICHARD |
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