Instructor, Internal Medicine, Mayo Medical School
Occupational Medicine
Dr. Richard D. Newcomb, MD
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Richard Newcomb practices Occupational Medicine. Richard Newcomb has written publications. He has 51 publications published with PubMed. The lastest paper is: 'Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas.'
Publications
- A survey of physicians' perceptions of their health care needs.
- Self-Report of Tobacco Use Status: Comparison of Paper-Based Questionnaire, Online Questionnaire, and Direct Face-to-Face Interview-Implications for Meaningful Use.
- Protective eyewear selection for interventional fluoroscopy.
- Using artificial neural networks to classify unknown volatile chemicals from the firings of insect olfactory sensory neurons.
- Predicting odorant chemical class from odorant descriptor values with an assembly of multi-layer perceptrons.
- A PCR-directed cell-free approach to optimize protein expression using diverse fusion tags.
- Characterisation of two alcohol acyltransferases from kiwifruit (Actinidia spp.) reveals distinct substrate preferences.
- Patterns of mitochondrial haplotype diversity in the invasive pest Epiphyas postvittana (Lepidoptera: Tortricidae).
- Biochemical characterisation of MdCXE1, a carboxylesterase from apple that is expressed during fruit ripening.
- Selective sweeps at the organophosphorus insecticide resistance locus, Rop-1, have affected variation across and beyond the {alpha}-esterase gene cluster in the Austra...
- Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects.
- DNA diagnostics of three armored scale species on kiwifruit in New Zealand.
- A genomics approach reveals that aroma production in apple is controlled by ethylene predominantly at the final step in each biosynthetic pathway.
- High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon.
- Phylogenetic Analysis of "Candidatus Phytoplasma australiense" Reveals Distinct Populations in New Zealand.
- Analyses of expressed sequence tags from apple.
- Multiple mutations and gene duplications conferring organophosphorus insecticide resistance have been selected at the Rop-1 locus of the sheep blowfly, Lucilia cuprina.
- The carboxylesterase gene family from Arabidopsis thaliana.
- Sucrose phosphate synthase genes in plants belong to three different families.
- DNA barcoding of the endemic New Zealand leafroller moth genera, Ctenopseustis and Planotortrix.
- Odorant receptors from the light brown apple moth (Epiphyas postvittana) recognize important volatile compounds produced by plants.
- Molecular basis of female-specific odorant responses in Bombyx mori.
- Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins.
- Selective pressures on Drosophila chemosensory receptor genes.
- Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening.
- Functional analysis of a Drosophila melanogaster olfactory receptor expressed in Sf9 cells.
- The squash aspartic proteinase inhibitor SQAPI is widely present in the cucurbitales, comprises a small multigene family, and is a member of the phytocystatin family.
- An alcohol acyl transferase from apple (cv. Royal Gala), MpAAT1, produces esters involved in apple fruit flavor.
- Pheromone binding proteins of Epiphyas postvittana (Lepidoptera: Tortricidae) are encoded at a single locus.
- Molecular cloning of an alpha-esterase gene cluster on chromosome 3r of Drosophila melanogaster.
- cDNA cloning, baculovirus-expression and kinetic properties of the esterase, E3, involved in organophosphorus resistance in Lucilia cuprina.
- A novel alpha-amylase gene is transiently upregulated during low temperature exposure in apple fruit.
- Isolation of alpha cluster esterase genes associated with organophosphate resistance in Lucilia cuprina.
- The acetylcholinesterase gene and organophosphorus resistance in the Australian sheep blowfly, Lucilia cuprina.
- Amplification of DNA from preserved specimens shows blowflies were preadapted for the rapid evolution of insecticide resistance.
- RNA interference in the light brown apple moth, Epiphyas postvittana (Walker) induced by double-stranded RNA feeding.
- Expressed sequence tags and proteomics of antennae from the tortricid moth, Epiphyas postvittana.
- Pernin: a novel, self-aggregating haemolymph protein from the New Zealand green-lipped mussel, Perna canaliculus (Bivalvia: Mytilidae).
- A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly.
- Binding of Bacillus thuringiensis delta-endotoxins Cry1Ac and Cry1Ba to a 120-kDa aminopeptidase-N of Epiphyas postvittana purified from both brush border membrane ves...
- Expressed sequence tags from the midgut of Epiphyas postvittana (Walker) (Lepidoptera: Tortricidae).
- Female-biased expression of odourant receptor genes in the adult antennae of the silkworm, Bombyx mori.
- Analysis of the circadian clock gene period in the sheep blow fly Lucilia cuprina.
- SNX-325, a novel calcium antagonist from the spider Segestria florentina.
- Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas.
- Processing of the egg-laying hormone (ELH) precursor in the bag cell neurons of Aplysia.
- The yellow condition in Drosophila melanogaster. A biological structuralist approach to the study of phenocopies.
- The sensitive period for yellow phenocopy induction in Drosophila melanogaster.
- Structural and biosynthetic properties of peptides in cone snail venoms.
- Increased production of extracellular glutamate by the mitochondrial glutaminase following neuronal death.
Schools
Mi State Univ Coll Human Med
Doctors Specialties
- Internal Medicine
- Occupational Medicine
Accepted Insurances
Education
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University of Michigan School of Public Health -
McGaw Medical Center of Northwestern University -
Michigan State University College of Human Medicine
Hospital
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Mayo Clinic - Rochester, Minnesota
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