Associate Professor, Pediatrics, Perelman School of Medicine
Pediatric Hematology & Oncology
Dr. Richard C. Aplenc, MD
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Richard Aplenc practices Pediatric Hematology & Oncology. He went to medical school at University of Virginia School of Medicine. Dr. Richard C. Aplenc is a published doctor. He published 86 publications, including: 'Inappropriate drug-donation practices in Bosnia and Herzegovina.'
Publications
- CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531.
- Burden of Influenza-Related Hospitalizations and Attributable Mortality in Pediatric Acute Lymphoblastic Leukemia.
- Comparison of administrative/billing data to expected protocol-mandated chemotherapy exposure in children with acute Myeloid leukemia: A report from the Children's Onc...
- The impact of chemotherapy shortages on COG and local clinical trials: A report from the Children's Oncology Group.
- Oxidant stress regulatory genetic variation in recipients and donors contributes to risk of primary graft dysfunction after lung transplantation.
- Association of Weekend Admission With Hospital Length of Stay, Time to Chemotherapy, and Risk for Respiratory Failure in Pediatric Patients With Newly Diagnosed Leukem...
- Predictors of antiemetic alteration in pediatric acute Myeloid leukemia.
- Acquired isochromosome 12p, somatic TP53 and PTEN mutations, and a germline ATM variant in an adolescent male with concurrent acute megakaryoblastic Leukemia and media...
- Effect of body mass in children with hematologic malignancies undergoing allogeneic bone marrow transplantation.
- TPMT and MTHFR genotype is not associated with altered risk of thioguanine-related sinusoidal obstruction syndrome in pediatric acute lymphoblastic Leukemia: A report ...
- Dexrazoxane exposure and risk of secondary acute Myeloid leukemia in pediatric oncology patients.
- Establishing a high-risk neuroblastoma cohort using the pediatric health information system database.
- Outcome of Pediatric Acute Myeloid Leukemia Patients Receiving Intensive Care in the United States.
- Patient and hospital factors associated with induction mortality in acute lymphoblastic Leukemia.
- CLL/SLL diagnosed in an adolescent.
- Zoonotic infections in pediatric patients with acute Leukemia.
- Induction mortality, ATRA administration, and resource utilization in a nationally representative cohort of children with acute promyelocytic Leukemia in the United St...
- Leveraging administrative data to monitor rituximab use in 2875 patients at 42 freestanding children's hospitals across the United States.
- Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine directed therapy.
- Chimeric antigen receptor-modified T cells for acute lymphoid Leukemia.
- IL1RN Coding Variant Is Associated with Lower Risk of Acute Respiratory Distress Syndrome and Increased Plasma IL1RA.
- Induction mortality and resource utilization in children treated for acute Myeloid leukemia at free-standing pediatric hospitals in the United States.
- Epidemiology of childhood acute Myeloid leukemia.
- Assembly of a cohort of children treated for acute Myeloid leukemia at free-standing children's hospitals in the United States using an administrative database.
- The use of palliative chemotherapy in pediatric oncology patients: A national survey of pediatric oncologists.
- Dexrazoxane use in pediatric patients with acute lymphoblastic or Myeloid leukemia from 1999 and 2009: Analysis of a national cohort of patients in the pediatric healt...
- Platelet factor 4 platelet levels are inversely correlated with steady-state platelet counts and with platelet transfusion needs in pediatric Leukemia patients.
- Germline genetic variation and treatment response on CCG-1891.
- Molecular Therapeutic Approaches for Pediatric Acute Myeloid Leukemia.
- Low-Dose, High-Frequency CPR Training Improves Skill Retention of In-Hospital Pediatric Providers.
- Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma.
- Pediatric phase I trial and pharmacokinetic study of dasatinib: a report from the children's oncology group phase I consortium.
- ANGPT2 Genetic Variant is Associated with Trauma-Associated Acute Lung Injury and Altered Plasma Angiopoietin-2 Isoform Ratio.
- Association of functional polymorphisms in CYP19A1 with aromatase inhibitor associated arthralgia in breast cancer survivors.
- Survival by race among children with extracranial solid tumors in the United States between 1985 and 2005.
- A phase 1 trial and pharmacokinetic study of cediranib, an orally bioavailable pan-vascular endothelial growth factor receptor inhibitor, in children and adolescents w...
- "Booster" training: Evaluation of instructor-led bedside cardiopulmonary resuscitation skill training and automated corrective feedback to improve cardiopulm...
- Steps forward in neuroblastoma genetic epidemiology.
- Risk factors for renal failure in pediatric patients with acute Myeloid leukemia: a retrospective cohort study.
- Cyclophosphamide-metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study.
- Pre-transplant lung function is predictive of survival following pediatric bone marrow transplantation.
- Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute Leukemia in childhood.
- Cefepime and mortality in pediatric acute myelogenous Leukemia: a retrospective cohort study.
- International variations in infection supportive care practices for paediatric patients with acute Myeloid leukaemia.
- Flow cytometric determination of Src phosphorylation in pediatric patients treated with dasatinib.
- Host genetic variants in the interleukin-6 promoter predict poor outcome in patients with estrogen receptor-positive, node-positive breast cancer.
- Association of human NAD(P)H:quinone oxidoreductase 1 (NQO1) polymorphism with development of acute lung injury.
- Hematopoietic colony-stimulating factor priming does not influence survival in acute Myeloid leukemia: a meta-analysis of randomized trials.
- Slow efavirenz metabolism genotype is common in Botswana.
- Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma.
- Unrelated donor bone marrow transplantation for children with acute Myeloid leukemia beyond first remission or refractory to chemotherapy.
- Respiratory syncytial virus infections in children with acute Myeloid leukemia: a report from the Children''s Oncology Group.
- Infections in pediatric acute Myeloid leukemia: lessons learned and unresolved questions.
- Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute Myeloid leukemia: a report from the Children''s Oncology Group.
- In response to "Drug metabolizing enzyme polymorphisms predict clinical outcome in a node-positive breast cancer cohort".
- Inferior outcomes for overweight children undergoing allogeneic stem cell transplantation.
- Pharmacogenetics of acute lymphoblastic Leukemia treatment response.
- X-linked lymphoproliferative disease with a novel SH2D1A gene mutation.
- Interleukin-1 alpha genotype and outcome of unrelated donor haematopoietic stem cell transplantation for Chronic myeloid leukaemia.
- Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury.
- Ethnicity and survival in childhood acute Myeloid leukemia: a report from the Children''s Oncology Group.
- Unrelated donor or partially matched related donor peripheral stem cell transplant with CD34+ selection and CD3+ addback for pediatric patients with Leukemias.
- Drug-metabolizing enzyme polymorphisms predict clinical outcome in a node-positive breast cancer cohort.
- No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood Leukemia.
- Identification of HLA-DQalpha and -DRbeta residues associated with susceptibility and protection to epithelial ovarian cancer.
- Safety and efficacy of gemtuzumab ozogamicin in pediatric patients with advanced CD33+ acute Myeloid leukemia.
- Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic Leukemia.
- Unrelated donor bone marrow transplantation for children with severe aplastic Anemia: minimal GVHD and durable engraftment with partial T cell depletion.
- CYP3A4, CYP3A5, and CYP3A43 genotypes and haplotypes in the etiology and severity of prostate cancer.
- Outcomes of transplantation with partial T-cell depletion of matched or mismatched unrelated or partially matched related donor bone marrow in children and adolescents...
- Genetic polymorphisms of CYP1A1, CYP2D6, GSTM1, and GSTT1 and susceptibility to acute lymphoblastic Leukemia in Indian children.
- Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia.
- An unexpectedly high incidence of Epstein-Barr virus lymphoproliferative disease after CD34+ selected autologous peripheral blood stem cell transplant in neuroblastoma.
- Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute Myeloid leukemia: Children's Cancer Group Study 2941.
- Pharmacogenetics of gemtuzumab-associated hepatic sinusoidal occlusion syndrome after hematopoietic stem cell transplant.
- GST polymorphisms and occurrence of second neoplasms after treatment of childhood Leukemia.
- Randomized trial of busulfan vs total body irradiation containing conditioning regimens for children with acute lymphoblastic Leukemia: a Pediatric Blood and Marrow Tr...
- CYP3A genotypes and treatment response in paediatric acute lymphoblastic leukaemia.
- Group sequential methods and sample size savings in biomarker-disease association studies.
- Differential bone marrow aspirate DNA yields from commercial extraction kits.
- Cytoplasmic micro heavy chain confers sensitivity to dexamethasone-induced apoptosis in early B-lineage acute lymphoblastic Leukemia.
- Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer.
- Acute Myeloid leukaemia in children.
- Inappropriate drug-donation practices in Bosnia and Herzegovina.
- Medical relief in central Bosnia.
Schools
University of Virginia Main Campus
University Of California San Diego
Chop
Procedures Preformed
- Bone Marrow Transplant
Conditions Treated
- Anemia
- Chronic Myeloid Leukemia (CML)
- Lymphocytosis
- Lymphoma
- View All
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Education
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Children's Hospital of Philadelphia -
University of California San Diego -
University of Virginia School of Medicine
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