Professor, Pathology and Laboratory Medicine, UCLA School of Medicine
Pathology
Dr. Richard A. Gatti, MD
|
|
Give Review
Doctor Richard A. Gatti, MD practices Pathology. He went to medical school at Saint Louis University School of Medicine. Saint Louis University School of Medicine has a rank of 67 in research and a 57 in primary care Richard Gatti is also a published MD. He has 60 paper published. The most recent paper is: RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8.
Publications
- Nijmegen Breakage Syndrome Detected by Newborn Screening for T Cell Receptor Excision Circles (TRECs).
- Mutation of Senataxin Alters Disease-Specific Transcriptional Networks in Patients with Ataxia with Oculomotor Apraxia Type 2.
- A New Series of Small Molecular Weight Compounds Induce Read Through of All Three Types of Nonsense Mutations in the ATM Gene.
- ATM-Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response.
- Rapid and Progressive Pulmonary Fibrosis in 2 Families with DNA Repair Deficiencies of Undetermined Etiology.
- Common copy number variations in fifty radiosensitive cell lines.
- Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia.
- Comprehensive Profiling of Radiosensitive Human Cell Lines with DNA Damage Response Assays Identifies the Neutral Comet Assay as a Potential Surrogate for Clonogenic S...
- DNA double strand break repair is defective in pediatric systemic lupus erythematosus.
- Assessing 'radiosensitivity' with kinetic profiles of ?-H2AX, 53BP1 and BRCA1 foci.
- Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum.
- Stable Brain ATM Message and Residual Kinase-Active ATM Protein in Ataxia-Telangiectasia.
- Heterotopic Purkinje cells in ataxia-telangiectasia.
- High throughput screening of small molecule libraries for modifiers of radiation responses.
- A history of bone marrow transplantation.
- MicroRNAs: new players in the DNA damage response.
- AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling.
- ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.
- ATM is down-regulated by N-Myc-regulated microRNA-421.
- Ataxia-telangiectasia with hyper-IgM and Wilms tumor: fatal reaction to irradiation.
- DNA double strand break repair defects, primary immunodeficiency disorders, and 'radiosensitivity'.
- High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones.
- Phenotypic variations between affected siblings with ataxia-telangiectasia: ataxia-telangiectasia in Japan.
- Nonaminoglycoside compounds induce readthrough of nonsense mutations.
- Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.
- Clinical radiation sensitivity with DNA repair disorders: an overview.
- Rapid flow cytometry-based structural maintenance of chromosomes 1 (SMC1) phosphorylation assay for identification of ataxia-telangiectasia homozygotes and heterozygotes.
- Simultaneous presentation of 2 rare hereditary immunodeficiencies: IL-12 receptor beta1 deficiency and ataxia-telangiectasia.
- New approaches to treatment of primary immunodeficiencies: fixing mutations with chemicals.
- Correction of prototypic ATM splicing mutations and aberrant ATM function with antisense morpholino oligonucleotides.
- Immunodeficiency, radiosensitivity, and the XCIND syndrome.
- ATM mutations in Italian families with ataxia telangiectasia include two distinct large genomic deletions.
- Intact T cell responses in ataxia telangiectasia.
- Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.
- ATM mutations, haplotype analysis, and immunological status of Russian patients with ataxia telangiectasia.
- A 700-kb physical and transcription map of the cervical cancer tumor suppressor gene locus on chromosome 11q13.
- Post-irradiation phosphorylation of structural maintenance chromosome 1 (SMC1) is independent of the Fanconi protein pathway.
- Functional significance of a deep intronic mutation in the ATM gene and evidence for an alternative exon 28a.
- Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.
- Immunoassay to measure ataxia-telangiectasia mutated protein in cellular lysates.
- Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons.
- ATM protein purified from vaccinia virus expression system: DNA binding requirements for kinase activation.
- Five haplotypes account for fifty-five percent of ATM mutations in Brazilian patients with ataxia telangiectasia: seven new mutations.
- Nonclassical splicing mutations in the coding and noncoding regions of the ATM Gene: maximum entropy estimates of splice junction strengths.
- Improved diagnostic testing for ataxia-telangiectasia by immunoblotting of nuclear lysates for ATM protein expression.
- Ataxia-telangiectasia: diagnosis and treatment.
- Independent mutational events are rare in the ATM gene: haplotype prescreening enhances mutation detection rate.
- ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region.
- Medulloblastoma with adverse reaction to radiation therapy in nijmegen breakage syndrome.
- Comprehensive scanning of the ATM gene with DOVAM-S.
- ATM mutations on distinct SNP and STR haplotypes in ataxia-telangiectasia patients of differing ethnicities reveal ancestral founder effects.
- Early diagnosis of ataxia-telangiectasia using radiosensitivity testing.
- Nijmegen breakage syndrome: clinical characteristics and mutation analysis in eight unrelated Russian families.
- TCL-1, MTCP-1 and TML-1 gene expression profile in non-leukemic clonal proliferations associated with ataxia-telangiectasia.
- Dubowitz syndrome is a complex comprised of multiple, genetically distinct and phenotypically overlapping disorders.
- Mass spectrometry-based tissue imaging of small molecules.
- Homozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks.
- SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs.
- RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8.
Schools
Saint Louis University School of Medicine
Doctors Specialties
- Pediatrics
- Pathology
Accepted Insurances
Education
-
University of Minnesota at Fairview -
Saint Louis University School of Medicine
Hospital
-
Ronald Reagan UCLA Medical Center
Helpful Reviews
Similar Doctors
|
|
Dr. Ashley S. Margol, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Debra L. Tang, MD |
|
|
Dr. Griselda Alvarez, MD |
|
|
Dr. Alan D. Alter, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Mamie V. Barrow, MD |
|
|
Dr. David H. Bolour, MD |
|
|
Dr. Rama Paliwal, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Michelle T. Essig, MD |
|
|
Dr. Charles R. Lassman, MD
This Doctor is OpenDoctor Recommended.
 This doctor has more publications
|
|
|
Dr. Min Huang, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Paul Mischel, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Sharon L. Hirschowitz, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Angela K. Weiner, MD |