Professor, Medicine, Vanderbilt University School of Medicine
Pulmonology
Dr. R Peebles, MD
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Peebles practices Pulmonology. He studied medicine at Vanderbilt University School of Medicine. R Peebles, MD is a published MD. He published 78 publications, including: 'Viral infections in asthma.'
Publications
- STAT6 signaling attenuates IL-17-producing γδ T cells during acute Klebsiella pneumoniae infection.
- Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis.
- Interferon response and respiratory virus control are preserved in bronchial epithelial cells in Asthma.
- Fractional exhaled nitric oxide change in pediatric patients after emergency department care of Asthma exacerbations.
- Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil and CCL8-dependent manner.
- A comprehensive analysis of transfection-assisted delivery of iron oxide nanoparticles to dendritic cells.
- Deficiency of gp91phox Inhibits Allergic Airway Inflammation.
- PGI2 signaling inhibits antigen uptake and increases migration of immature dendritic cells.
- IL-17A inhibits airway reactivity induced by respiratory syncytial virus infection during allergic airway inflammation.
- STAT6 Deficiency Ameliorates Severity of Oxazolone Colitis by Decreasing Expression of Claudin-2 and Th2-Inducing Cytokines.
- IL-17A Induces STAT6-Independent Airway Mucous Cell Metaplasia.
- A New Horizon in Asthma: Inhibiting ILC Function.
- Viral infections in Asthma.
- Epidemiology of Asthma: the year in review.
- Dietary antioxidants and adult Asthma.
- Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5.
- Respiratory syncytial virus infection reduces beta2-adrenergic responses in human airway smooth muscle.
- Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion.
- IL-13 is associated with reduced illness and replication in primary respiratory syncytial virus infection in the mouse.
- Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice.
- The complex relationship between respiratory syncytial virus and allergy in lung Disease.
- Cutting Edge: Oseltamivir decreases T cell GM1 expression and inhibits clearance of respiratory syncytial virus: potential role of endogenous sialidase in antiviral im...
- STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection.
- Differential regulation of GM1 and asialo-GM1 expression by T cells and natural killer (NK) cells in respiratory syncytial virus infection.
- A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction.
- Dietary supplementation of omega-3 fatty acid-containing fish oil suppresses F2-isoprostanes but enhances inflammatory cytokine response in a mouse model of ovalbumin-...
- Attenuation of Chronic pulmonary inflammation in A2B adenosine receptor knockout mice.
- Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.
- Differential immune responses and Pulmonary pathophysiology are induced by two different strains of respiratory syncytial virus.
- Differential pathogenesis of respiratory syncytial virus clinical isolates in BALB/c mice.
- Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells.
- Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells.
- Nuclear factor kappa B induction in airway epithelium increases lung inflammation in allergen-challenged mice.
- Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels.
- Respiratory syncytial virus Disease mechanisms implicated by human, animal model, and in vitro data facilitate vaccine strategies and new therapeutics.
- A functional IL-13 receptor is expressed on polarized murine CD4+ Th17 cells and IL-13 signaling attenuates Th17 cytokine production.
- Allergen-induced airway hyperresponsiveness mediated by cyclooxygenase inhibition is not dependent on 5-lipoxygenase or IL-5, but is IL-13 dependent.
- Viral infections, atopy, and Asthma: is there a causal relationship?
- Pneumothorax-associated pleural eosinophilia in mice is interleukin-5 but not interleukin-13 dependent.
- Oxidant stress modulates murine allergic airway responses.
- Human metapneumovirus infection plays an etiologic role in acute Asthma exacerbations requiring hospitalization in adults.
- Pathogenesis of respiratory syncytial virus infection in the murine model.
- The relationship of rhinovirus-associated Asthma hospitalizations with inhaled corticosteroids and smoking.
- The role of IFN in respiratory syncytial virus pathogenesis.
- Respiratory syncytial virus infections in the adult Asthmatic--mechanisms of host susceptibility and viral subversion.
- Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness.
- Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
- Eotaxin-3 and interleukin-5 pleural fluid levels are associated with pleural fluid eosinophilia in post-coronary artery bypass grafting pleural effusions.
- PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression.
- Human TH17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production.
- DSCG reduces RSV-induced illness in RSV-infected mice.
- Bugs and Asthma: a different disease?
- Wheezing exacerbations in early childhood: evaluation, treatment, and recent advances relevant to the genesis of Asthma.
- Update on the role of prostaglandins in allergic lung inflammation: separating friends from foes, harder than you might think.
- RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules.
- Functional polymorphism of the promoter region of the prostacyclin synthase gene and severity of RSV infection in hospitalized children.
- Induction and function of lipocalin prostaglandin D synthase in host immunity.
- PGI2 as a regulator of CD4+ subset differentiation and function.
- Highlights from the annual scientific assembly: patient-centered approaches to Asthma management: strategies for treatment and management of Asthma.
- IL-13 Regulates Th17 Secretion of IL-17A in an IL-10-Dependent Manner.
- Pleural fluid levels of vascular cell adhesion molecule-1 are elevated in eosinophilic pleural effusions.
- Cyclooxygenase inhibition augments allergic inflammation through CD4-dependent, STAT6-independent mechanisms.
- A mechanistic advance in understanding RSV pathogenesis, but still a long way from therapy.
- Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo.
- Pharmacologic advances in the treatment and prevention of respiratory syncytial virus.
- Novel concepts in virally induced Asthma.
- Anaphylaxis and anaphylactoid reactions. A guide to prevention, recognition, and emergent treatment.
- Anaphylactic shock: pathophysiology, recognition, and treatment.
- Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2.
- The spectrum and treatment of angioedema.
- Viruses and Asthma.
- Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production.
- Bacteria and Asthma: more there than we thought.
- The ever-expanding role of prostanoids in regulating immune responses.
- Viral respiratory tract infections and Asthma: the course ahead.
- Expression of activation markers on alveolar macrophages in allergic Asthmatics after endobronchial or whole-lung allergen challenge.
- Respiratory syncytial virus and reactive airway Disease.
Schools
Vanderbilt University
Conditions Treated
- Asthma
- COPD (Chronic Obstructive Pulmonary Disease)
- Dermatitis
- Sleep Apnea
Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
Education
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Vanderbilt University -
Johns Hopkins University -
Vanderbilt University School of Medicine
Hospital
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Vanderbilt Hospital and Clinics
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