Assistant Professor, Pediatrics, University of Pittsburgh School of Medicine

Pediatric Infectious Disease

Philana works in the field of Pediatric Infectious Disease. He went to medical school at Northeast Ohio Medical University. Dr. Philana L. Lin is also published. He has 37 publications published. The lastest publication: "The Effects of B cell Depletion on early Mycobacterium tuberculosis infection in Cynomolgus Macaques.'

Publications

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• The Effects of B cell Depletion on early Mycobacterium tuberculosis infection in Cynomolgus Macaques.
• Immunology studies in non-human primate models of tuberculosis.
• Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.
• PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis.
• A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment.
• Early Changes by (18)Fluorodeoxyglucose positron emission tomography coregistered with computed tomography predict outcome after Mycobacterium tuberculosis infection i...
• In vivo imaging in an ABSL-3 regional biocontainment laboratory.
• Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing.
• Altered Neutrophil Counts at Diagnosis of Invasive Meningococcal Infection in Children.
• Differential Virulence and Disease Progression following Mycobacterium tuberculosis Complex Infection of the Common Marmoset (Callithrix jacchus).
• Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms.
• Early Trends for Invasive Pneumococcal Infections in Children After the Introduction of the 13-valent Pneumococcal Conjugate Vaccine.
• Changes in Pediatric Streptococcus pneumoniae Serotype 19A Invasive Infections in Children from 1993-2011.
• Activated B Cells in the Granulomas of Nonhuman Primates Infected with Mycobacterium tuberculosis.
• CD4 T cell depletion exacerbates acute Mycobacterium tuberculosis while reactivation of latent infection is dependent on severity of tissue depletion in cynomolgus mac...
• The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis i...
• Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection.
• Increase of Streptococcus pneumoniae serotype 6C at 8 children's hospitals in the United States from 1993-2009.
• Simian immunodeficiency virus-induced changes in T cell cytokine responses in cynomolgus macaques with latent Mycobacterium tuberculosis infection are associated with ...
• Understanding latent tuberculosis: a moving target.
• Serotype 19A Is the most common serotype causing invasive pneumococcal infections in children.
• Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cyno...
• Infection with Helicobacter pylori is associated with protection against tuberculosis.
• Reactivation of latent tuberculosis in cynomolgus macaques infected with SIV is associated with early peripheral T cell depletion and not virus load.
• Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model.
• Chronic granulomatous disease in an adolescent with recurrent impetigo and cholecystectomy.
• Comparison of the effects of pathogenic simian human immunodeficiency virus strains SHIV-89.6P and SHIV-KU2 in cynomolgus macaques.
• Differences in reactivation of tuberculosis induced from anti-TNF treatments are based on bioavailability in granulomatous tissue.
• Tumor necrosis factor and tuberculosis.
• Early events in Mycobacterium tuberculosis infection in cynomolgus macaques.
• Tumor necrosis factor and chemokine interactions in the formation and maintenance of granulomas in tuberculosis.
• Safety and immunogenicity of the American Academy of Pediatrics--recommended sequential pneumococcal conjugate and polysaccharide vaccine schedule in pediatric solid o...
• TNF influences chemokine expression of macrophages in vitro and that of CD11b+ cells in vivo during Mycobacterium tuberculosis infection.
• Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection.
• Incidence of invasive pneumococcal disease in children 3 to 36 months of age at a tertiary care pediatric center 2 years after licensure of the pneumococcal conjugate ...
• Immunological concepts in tuberculosis diagnostics for non-human primates: a review.

Schools

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• Northeastern Ohio Universities College Of Medicine

• Mac Neal Mem Hospital

• University Health Center Of Pittsburgh

• University Of Chicago Hosps

Doctors Specialties

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• Pediatric Infectious Disease Medicine
• Pediatric Infectious Disease

Accepted Insurances

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• Aetna HMO
• Choice Plus POS II
• Blue Card PPO
• Blue Cross Blue Shield PPO
• Cigna HMO
• Cigna PPO
• Great West Healthcare-Cigna PPO
• Open Access
• Group Plan PPO
• Highmark Blue Cross Blue Shield
• Choice Care PPO
• Medicaid
• MultiPlan PPO
• PHCS Network PPO
• Choice Plus POS
• Options PPO

Education

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• University of Pittsburgh Medical Center
• University of Chicago
• Northeast Ohio Medical University

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