Chairman, Department of Medicine, Cedars-Sinai Medical Center
Pulmonology
Dr. Paul W. Noble, MD
|
|
Give Review
Paul Noble works in the field of Pulmonology. He went to NYU School of Medicine. Dr. Paul W. Noble has written publications. He has 102 publications published with PubMed. The lastest paper is: 'Pulmonary manifestations of Sjgren's syndrome.'
Publications
- The Role of TGF-β in the Association Between Primary Graft Dysfunction and Bronchiolitis Obliterans Syndrome.
- Hyaluronan as a therapeutic target in human Diseases.
- Cellular Mechanisms of Tissue Fibrosis. 7. New insights into the cellular mechanisms of Pulmonary fibrosis.
- A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis.
- Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis.
- Comprehensive assessment of the long-term safety of pirfenidone in patients with idiopathic Pulmonary fibrosis.
- Matrix Biology of Idiopathic Pulmonary Fibrosis: A Workshop Report of the National Heart, Lung, and Blood Institute.
- All-cause Mortality Rate in Patients with Idiopathic Pulmonary Fibrosis: Implications for the Design and Execution of Clinical Trials.
- Future Directions in Idiopathic Pulmonary Fibrosis Research: An NHLBI Workshop Report.
- SP-D Regulates Effector Cell Function and Fibrotic Lung Remodeling in Response to Bleomycin Injury.
- Long-term Exposure of Chemokine CXCL10 Causes Bronchiolitis-like Inflammation.
- Multiple stromal populations contribute to Pulmonary fibrosis without evidence for epithelial to mesenchymal transition.
- Role of CD44 in the organization of keratinocyte pericellular hyaluronan.
- Chronic in vivo ??-agonist treatment induces airway ??2AR dysfunction and exacerbates Lung inflammation in mice.
- Bayesian Probit Regression Model for the Diagnosis of Pulmonary Fibrosis: Proof-of-Principle.
- Forced Vital Capacity in Patients with Idiopathic Pulmonary Fibrosis: Test Properties and Minimal Clinically Important Difference.
- Efficacy of a tyrosine kinase inhibitor in idiopathic Pulmonary fibrosis.
- Ozone Inhalation Promotes CX3CR1-Dependent Maturation of Resident Lung Macrophages That Limit Oxidative Stress and Inflammation.
- Severe Lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44.
- End of an ERA: Lessons from Negative Clinical Trials in Idiopathic Pulmonary Fibrosis.
- Innate immune activation potentiates alloimmune Lung disease independent of chemokine (C-X-C motif) receptor 3.
- Cell Plasticity in Lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
- Ascertainment of Individual Risk of Mortality for Patients with Idiopathic Pulmonary Fibrosis.
- Comprehensive microRNA analysis in bleomycin-induced Pulmonary fibrosis identifies multiple sites of molecular regulation.
- Role of hyaluronan and hyaluronan-binding proteins in human asthma.
- Validated gene signatures of idiopathic Pulmonary fibrosis.
- Six-minute-walk test in idiopathic Pulmonary fibrosis: test validation and minimal clinically important difference.
- Airway Fibroblasts in Asthma Manifest an Invasive Phenotype.
- β-arrestin deficiency protects against Pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix.
- Extracorporeal Membrane Oxygenation for Severe Refractory Respiratory Failure Secondary to 2009 H1N1 Influenza A.
- Recruited Exudative Macrophages Selectively Produce CXCL10 Following Non-Infectious Lung Injury.
- Hyaluronan as an immune regulator in human Diseases.
- CD44 deficiency is associated with increased bacterial clearance but enhanced Lung inflammation during Gram-negative pneumonia.
- The role of surfactant protein A in bleomycin-induced acute Lung injury.
- Inhibition of Pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4.
- Regulation of non-infectious Lung injury, inflammation, and repair by the extracellular matrix glycosaminoglycan hyaluronan.
- Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice.
- Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic Lung injury.
- Extracellular superoxide dismutase inhibits inflammation by preventing oxidative fragmentation of hyaluronan.
- Idiopathic Pulmonary fibrosis and Pulmonary hypertension: connecting the dots.
- CD44 is a negative regulator of acute Pulmonary inflammation and lipopolysaccharide-TLR signaling in mouse macrophages.
- Hyaluronan in tissue injury and repair.
- Matrix regulation of Lung injury, inflammation, and repair: the role of innate immunity.
- Idiopathic Pulmonary fibrosis: natural history and prognosis.
- Regulation of Lung injury and repair by Toll-like receptors and hyaluronan.
- Case study review.
- Cutting edge: TLR4 deficiency confers susceptibility to lethal oxidant Lung injury.
- Back to the future: historical perspective on the pathogenesis of idiopathic Pulmonary fibrosis.
- Analyses of efficacy end points in a controlled trial of interferon-gamma1b for idiopathic Pulmonary fibrosis.
- Idiopathic Pulmonary fibrosis: new insights into pathogenesis.
- Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced Pulmonary fibrosis.
- Regulation of Pulmonary fibrosis by chemokine receptor CXCR3.
- Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced Lung apoptosis.
- Idiopathic Pulmonary fibrosis. New insights into classification and pathogenesis usher in a new era therapeutic approaches.
- Time will tell: predicting survival in idiopathic Interstitial pneumonia.
- CD44 deficiency leads to enhanced neutrophil migration and Lung injury in Escherichia coli pneumonia in mice.
- Resolution of Lung inflammation by CD44.
- Signaling properties of hyaluronan receptors.
- A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine Lung.
- Patient experiences with Pulmonary fibrosis.
- Pirfenidone in patients with idiopathic Pulmonary fibrosis (CAPACITY): two randomised trials.
- Effect of interferon gamma-1b on survival in patients with idiopathic Pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial.
- The clinical course of patients with idiopathic Pulmonary fibrosis.
- Idiopathic Pulmonary fibrosis.
- The role of Toll-like receptors in non-infectious Lung injury.
- A placebo-controlled trial of interferon gamma-1b in patients with idiopathic Pulmonary fibrosis.
- Hyaluronan and its catabolic products in tissue injury and repair.
- IL-13-induced chemokine responses in the Lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling.
- Airway inflammation and remodeling in asthma. Lessons from interleukin 11 and interleukin 13 transgenic mice.
- A cytokine reborn? Endothelin-1 in Pulmonary inflammation and fibrosis.
- Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).
- Divergence in macrophage insulin-like growth factor-I (IGF-I) synthesis induced by TNF-alpha and prostaglandin E2.
- Induction and regulation of macrophage metalloelastase by hyaluronan fragments in mouse macrophages.
- IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling.
- The role of hyaluronan degradation products as innate alloimmune agonists.
- Hyaluronan fragments induce plasminogen activator inhibitor-1 and inhibit urokinase activity in mouse alveolar macrophages: a potential mechanism for impaired fibrinol...
- Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages.
- Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic Pulmonary fibrosis. A potential mechanism for the recruitment and activation of ne...
- Insulin-like growth factor-1 (IGF-1) mRNA expression in bone marrow derived macrophages is stimulated by chrysotile asbestos and bleomycin. A potential marker for a re...
- CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex.
- Transforming growth factor-beta primes macrophages to express inflammatory gene products in response to particulate stimuli by an autocrine/paracrine mechanism.
- Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages.
- Hyaluronan fragments synergize with interferon-gamma to induce the C-X-C chemokines mig and interferon-inducible protein-10 in mouse macrophages.
- Development of functional diversity in mouse macrophages. Mutual exclusion of two phenotypic states.
- Inhibition of interferon gamma induced interleukin 12 production: a potential mechanism for the anti-inflammatory activities of tumor necrosis factor.
- Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.
- Functional switching of macrophage responses to tumor necrosis factor-alpha (TNF alpha) by interferons. Implications for the pleiotropic activities of TNF alpha.
- Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells.
- The ability to recognize phosphatidylserine on apoptotic cells is an inducible function in murine bone marrow-derived macrophages.
- Regulation of hyaluronan-induced chemokine gene expression by IL-10 and IFN-gamma in mouse macrophages.
- Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages.
- Pulmonary manifestations of Sjögren's syndrome.
- A critical assessment of treatment options for idiopathic Pulmonary fibrosis.
- Stimulation of inducible nitric oxide synthase in rat liver by hyaluronan fragments.
- Regulation of plasminogen activator inhibitor-1 and urokinase by hyaluronan fragments in mouse macrophages.
- Enhanced expression of IL-12 associated with Th1 cytokine profiles in active Pulmonary sarcoidosis.
- Hyaluronan fragments induce nitric-oxide synthase in murine macrophages through a nuclear factor kappaB-dependent mechanism.
- Extensive surface phenotyping of alveolar macrophages in interstitial Lung disease.
- Definition of a lipopolysaccharide-responsive element in the 5'-flanking regions of MuRantes and crg-2.
- Leptin regulates proinflammatory immune responses.
- Hyaluronan synthase 2 regulates fibroblast senescence in Pulmonary fibrosis.
Schools
NEW YORK UNIV SCH OF MED
Procedures Preformed
- Thoracentesis
- Ventilation Management
Conditions Treated
- Acidosis
- Alkalosis
- Bronchitis
- Collapsed Lung (Pneumothorax)
- View All
Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
Education
-
University of Colorado -
UCSF -
NYU School of Medicine
Hospital
-
Duke University Hospital -
Cedars-Sinai Medical Center
Drug Facts
| NPI NUMBER | 1942286307 | |
| NPPES Provider LastName | NOBLE | |
| NPPES Provider FirstName | PAUL | |
| NPPES Provider ZIPCode | 065191369 | |
| NPPES Provider State | CT | |
| Specialty Description | Pulmonary Disease | |
| Total Claim Count | 75.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1942286307 |
| Last Name Of The Provider | NOBLE |
| First Name Of The Provider | PAUL |
| View All |
Similar Doctors
|
|
Dr. Victor F. Tapson, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Sidney A. Mercado, MD |
|
|
Dr. Babak B. Saedi, MD |
|
|
Dr. Andrea T. Feinberg, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Vijay Babu, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. David Balfe, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Nir Maghen, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Alyse M. Mousette, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Waylan Wong
This Doctor is OpenDoctor Recommended.
|