Professor, Medicine, University of Minnesota Medical School, Minneapolis
Emergency Medicine
Dr. Paul R. Pentel, MD
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Paul Pentel practices Emergency Medicine. He researched medicine at Stanford University School of Medicine. Stanford University School of Medicine is a top medical university. Stanford University School of Medicine has a rank of 2 in research and a 25 in primary care He received 1 awards: "Super Doctor". Doctor Paul R. Pentel, MD has written publications. He has 101 publications published with PubMed. The lastest paper is: 'Effects of cotinine on cigarette self-administration.' He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Scientific overview: 2013 BBC plenary symposium on tobacco addiction.
- Portion size effects on weight gain in a free living setting.
- Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alum.
- Stability of heroin, 6-monoacetylmorphine, and morphine in biological samples and validation of an LC-MS assay for delayed analyses of pharmacokinetic samples in rats.
- Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens.
- Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats.
- Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist.
- An oxycodone conjugate vaccine elicits oxycodone-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia.
- Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats.
- Combined active and passive immunization against nicotine: Minimizing monoclonal antibody requirements using a target antibody concentration strategy.
- A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats.
- Comparison of the behavioral effects of cigarette smoke and pure nicotine in rats.
- Passive immunization with a nicotine-specific monoclonal antibody decreases brain nicotine levels but does not precipitate withdrawal in nicotine-dependent rats.
- Combined active and passive immunization enhances the efficacy of immunotherapy against nicotine in rats.
- Stability of the nicotine metabolite ratio in ad libitum and reducing smokers.
- Compensatory nicotine self-administration in rats during reduced access to nicotine: an animal model of smoking reduction.
- Acetaldehyde, a major constituent of tobacco smoke, enhances behavioral, endocrine, and neuronal responses to nicotine in adolescent and adult rats.
- Effects of maternal intravenous nicotine administration on locomotor behavior in pre-weanling rats.
- Tobacco extract but not nicotine impairs the mechanical strength of fracture healing in rats.
- Effects of nicotine withdrawal on performance under a progressive-ratio schedule of sucrose pellet delivery in rats.
- Current status of immunologic approaches to treating tobacco dependence: vaccines and nicotine-specific antibodies.
- Safety and immunogenicity of a nicotine conjugate vaccine in current smokers.
- The TEAM project: the effectiveness of smoking cessation intervention with hospital patients.
- Reinstatement of nicotine self-administration in rats by presentation of nicotine-paired stimuli, but not nicotine priming.
- Hospital-based program for increasing the availability of emergency contraception: simulating nonprescription access.
- Lack of effect of 5HT3 antagonist in mediating subjective and behavioral responses to cotinine.
- Continuous nicotine infusion reduces nicotine self-administration in rats with 23-h/day access to nicotine.
- The Anti-(+)-Methamphetamine Monoclonal Antibody mAb7F9 Attenuates Acute (+)-Methamphetamine Effects on Intracranial Self-Stimulation in Rats.
- Pharmacokinetic correlates of the effects of a heroin vaccine on heroin self-administration in rats.
- Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats.
- Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats.
- New directions in nicotine vaccine design and use.
- Enhanced immunogenicity of a bivalent nicotine vaccine.
- Differential effects of passive immunization with nicotine-specific antibodies on the acute and chronic distribution of nicotine to brain in rats.
- Vaccination against nicotine does not prevent nicotine-induced changes in fetal nicotinic receptor binding and c-fos mRNA expression in rats.
- Changes in maternal and fetal nicotine distribution after maternal administration of monoclonal nicotine-specific antibody to rats.
- Monoclonal nicotine-specific antibodies reduce nicotine distribution to brain in rats: dose- and affinity-response relationships.
- Tissue-dependent effects of immunization with a nicotine conjugate vaccine on the distribution of nicotine in rats.
- Biomarkers of tobacco exposure or harm: application to clinical and epidemiological studies. 25-26 October 2001, Minneapolis, Minnesota.
- Preferences and practices among renters regarding smoking restrictions in apartment buildings.
- Maternal vaccination against nicotine reduces nicotine distribution to fetal brain in rats.
- Therapeutic doses of phenylpropanolamine increase supine systolic blood pressure.
- Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities.
- Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats.
- Effects of high dose alpha-1-acid glycoprotein on desipramine toxicity in rats.
- Effects of phenylpropanolamine and isometric exercise on blood pressure.
- Propranolol antagonism of phenylpropanolamine-induced hypertension.
- Tricyclic antidepressant poisoning. Management of arrhythmias.
- Encapsulated alkali ingestion has a characteristic endoscopic appearance.
- Myocardial necrosis due to intraperitoneal administration of phenylpropanolamine in rats.
- Pharmacokinetics and toxicity of high-dose human alpha 1-acid glycoprotein infusion in the rat.
- Nonreactive pupils due to monoamine oxidase inhibitor overdose.
- Physical assessment and differential diagnosis of the poisoned patient.
- Hemoperfusion for imipramine overdose: elimination of active metabolites.
- Myocardial injury after phenylpropanolamine ingestion.
- Lack of effect of hypertonic sodium bicarbonate on QRS duration in patients taking therapeutic doses of class IC antiarrhythmic drugs.
- Determination of the in vivo antigen-antibody affinity constant from the redistribution of desipramine in rats following administration of a desipramine-specific monoc...
- Pretreatment with drug-specific antibody reduces desipramine cardiotoxicity in rats.
- Cardiac drug toxicity: digitalis glycosides and calcium-channel and beta-blocking agents.
- Adaptation of the Müller method to allow quantitative characterization of the affinity and cross-reactivity of antibodies by competitive radioimmunoassay.
- Rapid administration of high-dose human antibody Fab fragments to dogs: pharmacokinetics and toxicity.
- Effects of carbamazepine on acute responses to smoked cocaine-base in human cocaine users.
- Drug-specific F(ab'')2 fragment reduces desipramine cardiotoxicity in rats.
- Redistribution of tricyclic antidepressants in rats using a drug-specific monoclonal antibody: dose-response relationship.
- Reversal of desipramine toxicity in rats using drug-specific antibody Fab' fragment: effects on hypotension and interaction with sodium bicarbonate.
- The effect of phenylpropanolamine on blood pressure during upright bicycle exercise in normal subjects.
- Flu-like symptoms associated with fluoxetine overdose: a case report.
- Hypertonic sodium bicarbonate partially reverses QRS prolongation due to flecainide in rats.
- Effects of alpha-1-acid glycoprotein administration on propranolol binding and beta blockade in rats.
- Effect of hypertonic sodium bicarbonate on encainide overdose.
- Individual variability in the blood pressure response to intravenous phenylpropanolamine: a pharmacokinetic and pharmacodynamic investigation.
- Clinical features and consequences of seizures due to cyclic antidepressant overdose.
- Pharmacokinetics and toxicity of high doses of antibody Fab fragments in rats.
- Large scale production and purification of paraquat and desipramine monoclonal antibodies and their Fab fragments.
- Inhibition of nicotine-induced seizures in rats by combining vaccination against nicotine with chronic nicotine infusion.
- Passive immunization against nicotine prevents nicotine alleviation of nicotine abstinence syndrome.
- Altered disposition of repeated nicotine doses in rats immunized against nicotine.
- Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain.
- Carvedilol affects the physiological and behavioral response to smoked cocaine in humans.
- Effects of labetalol treatment on the physiological and subjective response to smoked cocaine.
- Predictors of cardiovascular response to smoked cocaine in humans.
- A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats.
- Sex and menstrual cycle differences in the subjective effects from smoked cocaine in humans.
- Immunization of rats reduces nicotine distribution to brain.
- Effects of phenytoin on cocaine self-administration in humans.
- Effects of cotinine on cigarette self-administration.
- Effects of dynorphin A(1-13) on opiate withdrawal in humans.
- Variation in human plasma cholinesterase activity during low-dose cocaine administration.
- Cotinine: effects with and without nicotine.
- Active immunization alters the plasma nicotine concentration in rats.
- Safety of cotinine in humans: physiologic, subjective, and cognitive effects.
- Bacterial expression and characterization of an anti-desipramine single-chain antibody fragment.
- High-level secretion of two antibody single chain Fv fragments by Pichia pastoris.
- Nitric oxide contributes to desipramine-induced hypotension in rats.
- Cloning, expression, and purification of an anti-desipramine single chain antibody in NS/O myeloma cells.
- Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats.
- Smoked cocaine self-administration in females.
- Effects of recombinant drug-specific single chain antibody Fv fragment on [3H]-desipramine distribution in rats.
- Drug-specific antibodies as antidotes for tricyclic antidepressant overdose.
- Methodological issues in the administration of multiple doses of smoked cocaine-base in humans.
Schools
Stanford University School Of Medicine
Hennepin Co Med Center
Doctors Specialties
- Medical Toxicology
- Emergency Medicine
Accepted Insurances
Awards
- Super Doctor
Education
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Hennepin County Medical Center -
Stanford University School of Medicine
Hospital
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Hennepin County Medical Center
Drug Facts
| NPI NUMBER | 1154368983 | |
| NPPES Provider LastName | PENTEL | |
| NPPES Provider FirstName | PAUL | |
| NPPES Provider ZIPCode | 554151623 | |
| NPPES Provider State | MN | |
| Specialty Description | Internal Medicine | |
| Total Claim Count | 68.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1154368983 |
| Last Name Of The Provider | PENTEL |
| First Name Of The Provider | PAUL |
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