Physician
Hematology
Dr. Paul O. Schwarzenberger, MD
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Paul O. Schwarzenberger practices Hematology. He studied medicine at Medical College of Wisconsin Affiliated Hospitals. Paul Schwarzenberger is a published physician. He has 71 papers published. The most current publication "The treatment of malignant mesothelioma with a gene modified cancer cell line: a phase I study."
Publications
- Oncofetal antigen/immature laminin receptor protein in pregnancy and cancer.
- A Phase 2 Randomized Trial of Paclitaxel and Carboplatin with or without Panitumumab for First-Line Treatment of Advanced Non-Small-Cell Lung Cancer.
- Requirement of TPO/c-mpl for IL-17A-induced granulopoiesis and megakaryopoiesis.
- CD34+ hematopoietic stem cells support entry and replication of poliovirus: a potential new gene introduction route.
- Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer.
- Phase 2 trial of Allovectin-7 in advanced metastatic melanoma.
- Production, safety and antitumor efficacy of recombinant Oncofetal Antigen/immature laminin receptor protein.
- Critical role of IL-17 receptor signaling in acute TNBS-induced colitis.
- IL-17 receptor knockout mice have enhanced myelotoxicity and impaired hemopoietic recovery following gamma irradiation.
- Interleukin-17A: a T-cell-derived growth factor for murine and human mesenchymal stem cells.
- CD4+ T cell-independent DNA vaccination against opportunistic infections.
- Retrovirus molecular conjugates: a versatile and efficient gene transfer vector system for primitive human hematopoietic progenitor cells.
- Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destructi...
- Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis.
- Development of a gene therapy based bone marrow purging system for leukemias.
- Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection.
- Phase II randomized trial of vinorelbine and gemcitabine versus carboplatin and paclitaxel in advanced non-small-cell lung cancer.
- Dose escalation of docetaxel concomitant with hypofractionated, once weekly chest radiotherapy for non-small-cell lung cancer: a phase I study.
- Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice.
- Replication of an adenoviral vector controlled by the human telomerase reverse transcriptase promoter causes tumor-selective tumor lysis.
- IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance.
- Retrovirus molecular conjugates.
- Interleukin 17: an example for gene therapy as a tool to study cytokine mediated regulation of hematopoiesis.
- Lentiviral vectors for sustained transgene expression in human bone marrow-derived stromal cells.
- Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction.
- Hematopoietic stem cells.
- Marrow stem cells, mesenchymal progenitor cells, and stromal progeny.
- Chimerism analysis in sex-mismatched murine transplantation using quantitative real-time PCR.
- Acute alcohol intoxication suppresses the CXC chemokine response during endotoxemia.
- Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice.
- CD4+ T cell-independent vaccination against Pneumocystis carinii in mice.
- Interleukin-17 and lung host defense against Klebsiella pneumoniae infection.
- Efficient c-kit receptor-targeted gene transfer to primary human CD34-selected hematopoietic stem cells.
- Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense.
- Il-17 mobilizes peripheral blood stem cells with short- and long-term repopulating ability in mice.
- IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis.
- Retrovirus molecular conjugates. A novel, high transduction efficiency, potentially safety-improved, gene transfer system.
- Prolonged ethanol treatment enhances lipopolysaccharide/phorbol myristate acetate-induced tumor necrosis factor-alpha production in human monocytic cells.
- Immunotherapy-based treatment strategies for malignant mesothelioma.
- Poly-L-lysine-based molecular conjugate vectors: a high efficiency gene transfer system for human progenitor and leukemia cells.
- Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate.
- Gene-modified PA1-STK cells home to tumor sites in patients with malignant pleural mesothelioma.
- Inhibition of TNF-alpha processing and TACE-mediated ectodomain shedding by ethanol.
- Immunomodulation and adenoviral gene transfer to the lungs of nonhuman primates.
- Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis.
- Activation of tumor necrosis factor-alpha-converting enzyme-mediated ectodomain shedding by nitric oxide.
- Propylthiouracil reduces xenograft tumor growth in an athymic nude mouse prostate cancer model.
- Treatment of thrombotic thrombocytopenic purpura with the cryosupernatant fraction of plasma: a case report and review of the literature.
- Cloning and characterization of the prostate-specific membrane antigen promoter.
- IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cells.
- The treatment of malignant mesothelioma with a gene modified cancer cell line: a phase I study.
- IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines.
- Plasmacytoma in HIV disease: two case reports and review of the literature.
- Antitumor activity with the HSV-tk-gene-modified cell line PA-1-STK in malignant mesothelioma.
- Gene therapy for malignant mesothelioma: a novel approach for an incurable cancer with increased incidence in Louisiana.
- Adenoviral-mediated interferon-gamma gene therapy augments pulmonary host defense of ethanol-treated rats.
- Receptor-targeted recombinant adenovirus conglomerates: a novel molecular conjugate vector with improved expression characteristics.
- Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection.
- Targeted gene transfer to human hematopoietic progenitor cell lines through the c-kit receptor.
- Effects of nifedipine and indomethacin on leukotriene C4- and D4-induced coronary constriction at normal and reduced coronary perfusion in dogs.
- Treatment of mesothelioma with gene-modified PA1STK cells and ganciclovir: a phase I study.
- Dose escalation of once weekly oral vinorelbine concurrent with weekly split dose hypofractionated chest radiation for palliation of advanced non-small cell lung cance...
- Early stage breast cancer.
- IL-17 is a potent synergistic factor with GM-CSF in mice in stimulating myelopoiesis, dendritic cell expansion, proliferation, and functional enhancement.
- Targeted agents for chronic myelogenous leukemia: will that be the end of allogeneic bone marrow transplantation for that disease?
- Biochemical characterization of riboflavin carrier protein (RCP) in prostate cancer.
- Combination of CsA, MTX and low-dose, short-course mycophenolate mofetil for GVHD prophylaxis.
- IL-17F/IL-17R interaction stimulates granulopoiesis in mice.
- Phase I study of flavopiridol in combination with Paclitaxel and Carboplatin in patients with non-small-cell lung cancer.
- Randomized phase III trial comparing bexarotene (L1069-49)/cisplatin/vinorelbine with cisplatin/vinorelbine in chemotherapy-naive patients with advanced or metastatic ...
Doctors Specialties
- Medical Oncology
- Oncology
- Hematology
Accepted Insurances
Education
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National Institutes of Health Clinical Center -
Medical College of Wisconsin Affiliated Hospitals
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