Professor, Medicine, UCSF School of Medicine
Infectious Disease
Dr. Paul M. Sullam, MD
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Dr. Paul M. Sullam is an expert in the field of Infectious Disease. He went to medical school at University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine is ranked 10/19 in Research/PrimaryCare. Paul Sullam is also a published doctor. He has 81 publication published. The most recent publication is: Physical proximity and functional interplay of the glycoprotein Ib-IX-V complex and the Fc receptor FcgammaRIIA on the platelet plasma membrane.
Publications
- Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein.
- Oral streptococci utilize a siglec-like domain of serine-rich repeat adhesins to preferentially target platelet sialoglycans in human blood.
- Group B streptococcal serine-rich repeat proteins promote interaction with fibrinogen and vaginal colonization.
- Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae.
- Selective transport by SecA2: An expanding family of customized motor proteins.
- Differential Localization of the Streptococcal Accessory Sec Components and Implications for Substrate Export.
- Binding of Glycoprotein Srr1 of Streptococcus agalactiae to Fibrinogen Promotes Attachment to Brain Endothelium and the Development of Meningitis.
- The accessory Sec protein Asp2 modulates GlcNAc deposition on the serine rich repeat glycoprotein GspB.
- A specific interaction between SecA2 and a region of the preprotein adjacent to the signal peptide occurs during transport via the accessory Sec system.
- Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase.
- A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors.
- Characterization of the Fibrinogen Binding Domain of Bacteriophage Lysin from Streptococcus mitis.
- Asp2 and Asp3 Interact Directly with GspB, the Export Substrate of the Streptococcus gordonii Accessory Sec System.
- Conservation of Ebp-type Pilus Genes among Enterococci and Demonstration of Their Role in Adherence of Enterococcus faecalis to Human Platelets.
- Transport of preproteins by the accessory Sec system requires a specific domain adjacent to the signal peptide.
- The pneumococcal serine-rich repeat protein is an intra-species bacterial adhesin that promotes bacterial aggregation in vivo and in biofilms.
- Bacteriophage lysin mediates the binding of streptococcus mitis to human platelets through interaction with fibrinogen.
- Streptococcus mitis phage-encoded adhesins mediate attachment to {alpha}2-8-linked sialic acid residues on platelet membrane gangliosides.
- Characterization of Streptococcus gordonii SecA2 as a paralogue of SecA.
- The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier.
- Genetic diversity of arginine catabolic mobile element in Staphylococcus epidermidis.
- Characterization of the accessory Sec system of Staphylococcus aureus.
- Glycine residues in the hydrophobic core of the GspB signal sequence route export toward the accessory Sec pathway.
- Binding of the streptococcal surface glycoproteins GspB and Hsa to human salivary proteins.
- Two additional components of the accessory sec system mediating export of the Streptococcus gordonii platelet-binding protein GspB.
- Role of SraP, a Serine-Rich Surface Protein of Staphylococcus aureus, in binding to human platelets.
- Four proteins encoded in the gspB-secY2A2 operon of Streptococcus gordonii mediate the intracellular glycosylation of the platelet-binding protein GspB.
- The Streptococcus gordonii surface proteins GspB and Hsa mediate binding to sialylated carbohydrate epitopes on the platelet membrane glycoprotein Ibalpha.
- The Streptococcus gordonii platelet binding protein GspB undergoes glycosylation independently of export.
- Genomic organization and molecular characterization of SM1, a temperate bacteriophage of Streptococcus mitis.
- Pattern recognition by TREM-2: binding of anionic ligands.
- Role of the Serine-Rich Surface Glycoprotein Srr1 of Streptococcus agalactiae in the Pathogenesis of Infective Endocarditis.
- An accessory sec locus of Streptococcus gordonii is required for export of the surface protein GspB and for normal levels of binding to human platelets.
- Proteins PblA and PblB of Streptococcus mitis, which promote binding to human platelets, are encoded within a lysogenic bacteriophage.
- Clumping factor A mediates binding of Staphylococcus aureus to human platelets.
- Genetic loci of Streptococcus mitis that mediate binding to human platelets.
- A randomized, placebo-controlled study of rifabutin added to a regimen of clarithromycin and ethambutol for treatment of disseminated infection with Mycobacterium aviu...
- Acetylsalicylic acid reduces vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus ...
- Physical proximity and functional interplay of the glycoprotein Ib-IX-V complex and the Fc receptor FcgammaRIIA on the platelet plasma membrane.
- Platelet microbicidal proteins and neutrophil defensin disrupt the Staphylococcus aureus cytoplasmic membrane by distinct mechanisms of action.
- Primary septic arthritis and osteomyelitis due to Mycobacterium avium complex in a patient with AIDS.
- A simple, fluorescent method to internally label platelets suitable for physiological measurements.
- Phenotypic resistance to thrombin-induced platelet microbicidal protein in vitro is correlated with enhanced virulence in experimental endocarditis due to Staphylococc...
- Early manifestations of disseminated Mycobacterium avium complex disease: a prospective evaluation.
- Geographic and seasonal variation in Mycobacterium avium bacteremia among North American patients with AIDS.
- Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis.
- Rifabutin therapy for disseminated Mycobacterium avium complex infection.
- Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome.
- Inhibition of platelet binding and aggregation by streptococcal exopolysaccharide.
- Effect of thrombocytopenia on the early course of streptococcal endocarditis.
- Two controlled trials of rifabutin prophylaxis against Mycobacterium avium complex infection in AIDS.
- Role of the sar locus of Staphylococcus aureus in induction of endocarditis in rabbits.
- Platelet microbicidal protein alone and in combination with antibiotics reduces Staphylococcus aureus adherence to platelets in vitro.
- Fluconazole and platelet microbicidal protein inhibit Candida adherence to platelets in vitro.
- Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis.
- Efficacy of rifabutin in the treatment of disseminated infection due to Mycobacterium avium complex. The Rifabutin Treatment Group.
- The laminin alpha 1 chain Ile-Lys-Val-Ala-Val (IKVAV)-containing peptide promotes liver colonization by human colon cancer cells.
- Staphylococcus aureus induces platelet aggregation via a fibrinogen-dependent mechanism which is independent of principal platelet glycoprotein IIb/IIIa fibrinogen-bin...
- Synovial fluid eosinophilia.
- Cardiac tamponade with refeeding in malnutrition.
- Pathogenesis of endocarditis.
- Influence of the developmental state of valvular lesions on the antimicrobial activity of cefotaxime in experimental enterococcal infections.
- Antimicrobial activity of gentamicin in experimental enterococcal endocarditis.
- Pefloxacin therapy for experimental endocarditis caused by methicillin-susceptible or methicillin-resistant strains of Staphylococcus aureus.
- Paromomycin therapy of endemic amebiasis in homosexual men.
- The benefits of evaluating close associates of child tuberculin reactors from a high prevalence group.
- Use of arabinogalactan to obtain washed murine platelets free of contaminating plasma proteins and appropriate for studies of function, morphology, and thrombopoiesis.
- Therapeutic efficacy of teicoplanin in experimental enterococcal endocarditis.
- Mechanisms of platelet aggregation by viridans group streptococci.
- Role of immunoglobulin G in platelet aggregation by viridans group streptococci.
- Binding of viridans group streptococci to human platelets: a quantitative analysis.
- Role of platelets in endocarditis: clues from von Willebrand disease.
- Characterization of Staphylococcus aureus-platelet binding by quantitative flow cytometric analysis.
- Genes in the accessory sec locus of Streptococcus gordonii have three functionally distinct effects on the expression of the platelet-binding protein GspB.
- Determinants of the streptococcal surface glycoprotein GspB that facilitate export by the accessory Sec system.
- Binding of the Streptococcus gordonii surface glycoproteins GspB and Hsa to specific carbohydrate structures on platelet membrane glycoprotein Ibalpha.
- Purification, crystallization and preliminary X-ray diffraction analysis of the carbohydrate-binding region of the Streptococcus gordonii adhesin GspB.
- Asp3 mediates multiple protein-protein interactions within the accessory Sec system of Streptococcus gordonii.
- Mechanism of cell surface expression of the Streptococcus mitis platelet binding proteins PblA and PblB.
- Role of the serine-rich surface glycoprotein GspB of Streptococcus gordonii in the pathogenesis of infective endocarditis.
Schools
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
Boston University Med CtrUniv Hp
Cedars Sinai Med Center
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Education
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Boston University Medical Center -
Cedars-Sinai Medical Center -
University of Chicago Pritzker School of Medicine
Hospital
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San Francisco VA Medical Center -
UCSF Medical Center
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