Assistant Professor of Pediatrics, Massachusetts General Hospital
Pediatric Endocrinology
Dr. Paul A. Boepple, MD
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Doctor Paul A. Boepple, MD works in the field of Pediatric Endocrinology. He researched medicine at University of Vermont College of Medicine. He received 1 awards: "Regional Top Doctor". Paul Boepple is a published MD. He published 51 publications, including: 'Leptin levels in children with central precocious puberty.'
Publications
- Trial of Recombinant Follicle Stimulating Hormone (rFSH) Pre-treatment for GnRH-induced Fertility in Patients with Congenital Hypogonadotropic Hypogonadism.
- Reversal and Relapse of Hypogonadotropic Hypogonadism: Resilience and Fragility of the Reproductive Neuroendocrine System.
- Metabolic Effects of Roux-en-Y Gastric Bypass in Obese Adolescents and Young Adults.
- Fanconi-Bickel Syndrome and Autosomal Recessive Proximal Tubulopathy with Hypercalciuria (ARPTH) Are Allelic Variants Caused by GLUT2 Mutations.
- A genetic basis for functional hypothalamic amenorrhea.
- Safety of frequent venous blood sampling in a pediatric research population.
- The relative role of gonadal sex steroids and gonadotropin-releasing hormone pulse frequency in the regulation of follicle-stimulating hormone secretion in men.
- Relative roles of inhibin B and sex steroids in the negative feedback regulation of follicle-stimulating hormone in men across the full spectrum of seminiferous epithe...
- Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem ...
- Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism.
- The role of prior pubertal development, biochemical markers of testicular maturation, and genetics in elucidating the phenotypic heterogeneity of idiopathic hypogonado...
- Reversal of idiopathic hypogonadotropic hypogonadism.
- Digenic mutations account for variable phenoTypes in idiopathic hypogonadotropic hypogonadism.
- Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenoTypes.
- Importance of inhibin B in the regulation of FSH secretion in the human male.
- The longitudinal study of adrenal maturation during gonadal suppression: evidence that adrenarche is a gradual process.
- The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormon...
- Variation in the timing of puberty: clinical spectrum and genetic investigation.
- Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating horm...
- Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback.
- Is Obesity an outcome of gonadotropin-releasing hormone agonist administration? Analysis of growth and body composition in 110 patients with central precocious puberty.
- Unsustained or slowly progressive puberty in young girls: initial presentation and long-term follow-up of 20 untreated patients.
- Leptin levels in children with central precocious puberty.
- Clinical review 96: Differential control of gonadotropin secretion in the human: endocrine role of inhibin.
- The impact of reversible gonadal sex steroid suppression on serum leptin concentrations in children with central precocious puberty.
- Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility.
- The genetic and clinical heterogeneity of gonadotropin-releasing hormone deficiency in the human.
- Contour of the GnRH pulse independently modulates gonadotropin secretion in the human male.
- Inhibin B in males with gonadotropin-releasing hormone (GnRH) deficiency: changes in serum concentration after shortterm physiologic GnRH replacement--a clinical resea...
- Inhibin B secretion in males with gonadotropin-releasing hormone (GnRH) deficiency before and during long-term GnRH replacement: relationship to spontaneous puberty, t...
- Adrenal hypoplasia congenita with hypogonadotropic hypogonadism: evidence that DAX-1 mutations lead to combined hypothalmic and pituitary defects in gonadotropin produ...
- Defective regulation of glycoprotein free alpha-subunit in males with isolated gonadotropin-releasing hormone deficiency--a clinical research center study.
- Accuracy and reproducibility of clinical measures of testicular volume.
- Impact of sex steroids and their suppression on skeletal growth and maturation.
- Changes in growth and serum growth hormone and plasma somatomedin-C levels during suppression of gonadal sex steroid secretion in girls with central precocious puberty.
- Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty.
- Adrenarche and skeletal maturation during luteinizing hormone releasing hormone analogue suppression of gonadarche.
- Gonadotrophin-releasing hormone agonist treatment of central precocious puberty: an analysis of growth data in a developmental context.
- Sleep modulation of neuroendocrine function: developmental changes in gonadotropin-releasing hormone secretion during sexual maturation.
- Altered patterns of pituitary secretion and renal excretion of free alpha-subunit during gonadotropin-releasing hormone agonist-induced pituitary desensitization.
- Gonadotrophin-releasing hormone analogues as therapeutic probes in human growth and development: evidence from children with central precocious puberty.
- Serum melatonin in central precocious puberty is lower than in age-matched prepubertal children.
- Recurrent ovarian cysts in childhood: diagnosis of McCune-Albright syndrome by bone scan.
- Ovulation and Menstrual function of adolescent girls with central precocious puberty after therapy with gonadotropin-releasing hormone agonists.
- The natural history of autonomous gonadal function, adrenarche, and central puberty in gonadotropin-independent precocious puberty.
- Improving hypertension detection and referral in an ambulatory setting.
- Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation.
- Adolescent Obesity and bariatric surgery.
- Interplay between dose and frequency of GnRH administration in determining pituitary gonadotropin responsiveness.
- Rathke''s cleft cysts in children and adolescents: association with female puberty.
Schools
University Of Vermont College Of Medicine
Duke University Med Center
Massachusetts General Hospital
Conditions Treated
- Diabetes Type 2
- Goiter
- Hyperlipidemia
- Hypothyroidism
- View All
Doctors Specialties
- Pediatric Endocrinology
Accepted Insurances
Awards
- Regional Top Doctor
Education
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Massachusetts General Hospital -
Duke University Hospital -
University of Vermont College of Medicine
Hospital
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Newton-Wellesley Hospital -
Massachusetts General Hospital
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