Physician
Family Medicine
Dr. Patrick L. Leong, DO
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Patrick Leong is an expert in the field of Family Medicine. He received awards:"Meaningful Use Stage 1 Certification". Patrick Leong is a published physician. He published 21 publications, including: 'Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli.' Dr. Patrick L. Leong, DO accepts Medicare payments and is registered with Medicare.gov.
Publications
- Na+/K+-ATPase activity during early development and growth of an Antarctic sea urchin.
- Energy metabolism during embryonic development and larval growth of an Antarctic sea urchin.
- Glucocorticoids increase sodium pump alpha(2)- and beta(1)-subunit abundance and mRNA in rat skeletal muscle.
- Short-term K(+) deprivation provokes insulin resistance of cellular K(+) uptake revealed with the K(+) clamp.
- Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli.
- Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles.
- Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance.
- Phenol injury-induced hypertension stimulates proximal tubule Na+/H+ exchanger activity.
- Modest dietary K+ restriction provokes insulin resistance of cellular K+ uptake and phosphorylation of renal outer medulla K+ channel without fall in plasma K+ concent...
- Effects of ACE inhibition on proximal tubule sodium transport.
- Redistribution of myosin VI from top to base of proximal tubule microvilli during acute hypertension.
- Differential traffic of proximal tubule Na+ transporters during hypertension or PTH: NHE3 to base of microvilli vs. NaPi2 to endosomes.
- Acute hypotension induced by aortic clamp vs. PTH provokes distinct proximal tubule Na+ transporter redistribution patterns.
- Mechanisms of pressure natriuresis: how blood pressure regulates renal sodium transport.
- Modest K+ restriction provokes insulin resistance of cellular K+ uptake without decrease in plasma K.
- Chronic renal injury-induced hypertension alters renal NHE3 distribution and abundance.
- Responses of proximal tubule sodium transporters to acute injury-induced hypertension.
- Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension.
- Diuretic response to acute hypertension is blunted during angiotensin II clamp.
- Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity.
Schools
University of Osteopathic Medicine And Health Sciences College of Osteopathic Medicine
Des Moines General Hospital
Des Moines General Ia
Des Moines General
Doctors Specialties
- Osteopathic Manipulative Therapy
- Family Medicine
Accepted Insurances
Awards
- Meaningful Use Stage 1 Certification
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