Physician
Family Medicine
Dr. Patricia Hinkle, MD
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Patricia Hinkle, MD is an expert in the field of Family Medicine. He studied medicine at University of Missouri - Kansas City School of Medicine. Doctor Patricia Hinkle, MD is a published doctor as well. He has 42 publications published. The latest was: Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane. Patricia Hinkle is registered with Medicare and accepts Medicare payments.
Publications
- Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane.
- Ostα-/- mice are not protected from western diet-induced weight gain.
- Ostα-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity.
- Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish.
- siRNA Screen Identifies the Phosphatase Acting on the G Protein-Coupled Thyrotropin-Releasing Hormone Receptor.
- Detection of G protein-coupled receptors by immunofluorescence microscopy.
- Ca(2+)-induced Ca(2+) release in the pancreatic beta-cell: direct evidence of endoplasmic reticulum Ca(2+) release.
- Thyrotropin-releasing hormone receptor processing: role of ubiquitination and proteasomal degradation.
- Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides.
- Endoplasmic reticulum calcium storage and release in cells expressing misfolded growth hormone.
- Role of TRH receptors as possible mediators of analeptic actions of TRH-like peptides.
- Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation.
- Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers.
- A novel TRH analog, Glp-Asn-Pro-D-Tyr-D-TrpNH2, binds to [3H][3-Me-His2]TRH-labelled sites in rat hippocampus and cortex but not pituitary or heterologous cells expres...
- Dimerization of the thyrotropin-releasing hormone receptor potentiates hormone-dependent receptor phosphorylation.
- Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone.
- Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies.
- Regulation of endogenous melanocortin-4 receptor expression and signaling by glucocorticoids.
- Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor.
- Regulated dimerization of the thyrotropin-releasing hormone receptor affects receptor trafficking but not signaling.
- Fate of internalized thyrotropin-releasing hormone receptors monitored with a timer fusion protein.
- Agonist-dependent up-regulation of thyrotrophin-releasing hormone receptor protein.
- Functional expression of frog and rainbow trout melanocortin 2 receptors using heterologous MRAP1s.
- Use of chimeric melanocortin-2 and -4 receptors to identify regions responsible for ligand specificity and dependence on melanocortin 2 receptor accessory protein.
- Regulation of G protein-coupled receptor signaling: specific dominant-negative effects of melanocortin 2 receptor accessory protein 2.
- Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation.
- Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase.
- Subcellular trafficking of the TRH receptor: effect of phosphorylation.
- Opposite effects of the melanocortin-2 (MC2) receptor accessory protein MRAP on MC2 and MC5 receptor dimerization and trafficking.
- Structure and function of the melanocortin2 receptor accessory protein (MRAP).
- Regions of melanocortin 2 (MC2) receptor accessory protein necessary for dual topology and MC2 receptor trafficking and signaling.
- Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences.
- TRH and related peptides: homeostatic regulators of glutamate transmission?
- Misfolded growth hormone causes fragmentation of the Golgi apparatus and disrupts endoplasmic reticulum-to-Golgi traffic.
- Activation of MAPK by TRH requires clathrin-dependent endocytosis and PKC but not receptor interaction with beta-arrestin or receptor endocytosis.
- Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt's lymphoma cell line containing mutant p53 genes.
- Calcium responses to thyrotropin-releasing hormone, gonadotropin-releasing hormone and somatostatin in phospholipase css3 knockout mice.
- Rapid turnover of calcium in the endoplasmic reticulum during signaling. Studies with cameleon calcium indicators.
- Genetic alteration of phospholipase C beta3 expression modulates behavioral and cellular responses to mu opioids.
- Signal transduction and hormone-dependent internalization of the thyrotropin-releasing hormone receptor in cells lacking Gq and G11.
- Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin prom...
Doctors Specialties
- Family Medicine
Accepted Insurances
- Choice Plus POS II
- Anthem Blue Cross Blue Shield HMO
- Anthem Blue Cross Blue Shield PPO
- Blue Preferred Plus POS
- Blue Preferred Select
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- Commercial Insurance Company
- Coventry Health Care
- Coventry Health Care of Illinois PPO
- Health and Life PPO
- Platinum PPO
- Coventry Health Care of Kansas, Inc. PPO
- Coventry Health Care of Missouri PPO
- First Health (Coventry Health Care) PPO
- Golden Rule
- Group Health Cooperative
- HealthLink PPO
- Homestate Health Plan
- Medicare MCR
- Molina
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Education
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University of Missouri - Kansas City School of Medicine
Drug Facts
| NPI NUMBER | 1023217031 | |
| NPPES Provider LastName | HINKLE | |
| NPPES Provider FirstName | PATRICIA | |
| NPPES Provider ZIPCode | 637754204 | |
| NPPES Provider State | MO | |
| Specialty Description | Family Practice | |
| Total Claim Count | 5867.0 | |
| Distinct Opioid Count | 5.0 | |
| Opioid Claim Count | 196.0 | |
| Percent Opioid Claims | 3.34 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1023217031 |
| Last Name Of The Provider | HINKLE |
| First Name Of The Provider | PATRICIA |
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