Professor, Pediatrics, Pennsylvania State University College of Medicine
Pediatrics
Dr. Neal J. Thomas, MD
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Neal J. Thomas, MD works in the field of Pediatrics. He studied medicine at Medical University of South Carolina. He received 2 awards: "Fellow (FCCM)" and "Fellow (FAAP)". Neal Thomas is also a published doctor. He has 100 paper published. The most recent paper is: Effects of type IV phosphodiesterase inhibition on cardiac function in the presence and absence of catecholamines.
Publications
- Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology.
- Developing a Clinically Feasible Personalized Medicine Approach to Pediatric Septic Shock.
- Regulation of translation by upstream translation initiation codons of surfactant protein A1 (SP-A1) splice variants.
- Knockdown of Drosha in human alveolar type II cells alters expression of SP-A in culture: A pilot study.
- Competency in the "art" of pediatric mechanical ventilation*.
- The Impact of a Locally Applied Vibrating Device on Outpatient Venipuncture in Children.
- Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock.
- Outcome of Pediatric Acute Myeloid Leukemia Patients Receiving Intensive Care in the United States.
- Retrospective outcomes of glucose control in critically ill children.
- The nose knows what it wants: high-flow nasal cannula versus nasopharyngeal continuous positive airway pressure*.
- The Relationship of Fluid Administration to Outcome in the Pediatric Calfactant in Acute Respiratory Distress Syndrome Trial.
- Pediatric Calfactant in Acute Respiratory Distress Syndrome Trial.
- High frequency oscillation and airway pressure release ventilation in pediatric respiratory failure.
- Acute Lung Injury in Children-Kids Really Aren't Just "Little Adults"
- Assessing Pulmonary Arterial Hypertension in Infants With Severe Chronic Lung Disease of Infancy: A Role for a Pulmonary Artery Catheter?
- A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure.
- The kinetics of cardiopulmonary bypass: a dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass.
- Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray.
- The Influence of Developmental Age on the Early Transcriptomic Response of Children with Septic Shock.
- Validation of a gene expression-based subclassification strategy for pediatric septic shock.
- Surfactant protein genetics in community-acquired pneumonia: balancing the host inflammatory state.
- Dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass.
- Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products.
- Surfactant composition and biophysical properties are important in clinical studies.
- Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women.
- Defining acute lung disease in children with the oxygenation saturation index.
- Severe pulmonary hypertension associated with the acute motor sensory axonal neuropathy subtype of Guillain-Barré syndrome.
- Transmission of surfactant protein variants and haplotypes in children hospitalized with respiratory syncytial virus.
- Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass.
- Demographics of abusive head trauma in the Commonwealth of Pennsylvania.
- Temporal factors and the incidence of physical abuse in young children: decreased nonaccidental trauma during Child Abuse Prevention Month.
- Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock.
- Characterization of a human surfactant protein A1 (SP-A1) gene-specific antibody; SP-A1 content variation among individuals of varying age and pulmonary health.
- Assessment of parental presence during bedside pediatric intensive care unit rounds: effect on duration, teaching, and privacy.
- Palivizumab prophylaxis to prevent respiratory syncytial virus mortality after pediatric bone marrow transplantation: a decision analysis model.
- Surfactant protein A2 (SP-A2) variants expressed in CHO cells stimulate phagocytosis of Pseudomonas aeruginosa more than do SP-A1 variants.
- Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury.
- Opioids causing a back up in the pediatric intensive care unit? No solution yet.
- Family-based association tests suggest linkage between surfactant protein B (SP-B) (and flanking region) and respiratory distress syndrome (RDS): SP-B haplotypes and a...
- High-throughput DNA methylation profiling using universal bead arrays.
- The impact of pediatric trauma in the Amish community.
- Efficacy of bystander cardiopulmonary resuscitation and out-of-hospital automated external defibrillation as life-saving therapy in commotio cordis.
- A randomized controlled trial comparing three different techniques of nasojejunal feeding tube placement in critically ill children.
- Epoprostenol and home mechanical ventilation for pulmonary hypertension associated with chronic lung disease.
- Prospective assessment of guidelines for determining appropriate depth of endotracheal tube placement in children.
- Duration of cardiopulmonary resuscitation before extracorporeal rescue: how long is not long enough?
- Idiopathic thrombocytopenic purpura complicated by an intracranial hemorrhage secondary to an arteriovenous malformation.
- Cost-effectiveness of exogenous surfactant therapy in pediatric patients with acute hypoxemic respiratory failure.
- Altered chemokine response in an animal model of multiple organ dysfunction syndrome induced by zymosan.
- Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers.
- Gas gangrene secondary to Clostridium perfringens in pediatric oncology patients.
- Jading in the pediatric intensive care unit: Implications for healthcare providers of medically complex children.
- Amantadine penetration into cerebrospinal fluid of a child with influenza A encephalitis.
- Decreasing unplanned extubations: utilization of the Penn State Children's Hospital Sedation Algorithm.
- Magnesium sulfate for control of muscle rigidity and spasms and avoidance of mechanical ventilation in pediatric tetanus.
- F2-isoprostane and neuron-specific enolase in cerebrospinal fluid after severe traumatic brain injury in infants and children.
- Theophylline for acute renal vasoconstriction associated with tacrolimus: a new indication for an old therapeutic agent?
- Is the injured child different or just treated differently with respect to the development of multiple organ dysfunction syndrome?
- Plasma concentrations of defensins and lactoferrin in children with severe sepsis.
- Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis.
- A prospective assessment of the effect of aminophylline therapy on urine output and inflammation in critically ill children.
- The temporal version of the pediatric sepsis biomarker risk model.
- Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model.
- Myocardial revascularization for the third time. Clinical characteristics and follow-up.
- Biological and molecular characterizations of Toxoplasma gondii strains obtained from southern sea otters (Enhydra lutris nereis).
- Dual Sarcocystis neurona and Toxoplasma gondii infection in a Northern sea otter from Washington state, USA.
- Ultrastructure of tight junctions in prostaglandin-exposed rat stomach.
- Pediatric ECMO for severe quinidine cardiotoxicity.
- Biological characterisation of Sarcocystis neurona isolated from a Southern sea otter (Enhydra lutris nereis).
- Bicycle-related head injuries in South Carolina children: what can we do to prevent them?
- Semilunar valve switch procedure: autotransplantation of the native aortic valve to the pulmonary position in the Ross procedure.
- Myocardial calcification caused by secondary hyperparathyroidism due to dietary deficiency of calcium and vitamin D.
- Penn State Hershey--center for pediatric cardiovascular research.
- Cardiac failure in hemolytic uremic syndrome and rescue with extracorporeal life support.
- Hypovolemic shock in pediatric patients.
- Genetic variants of surfactant proteins A, B, C, and D in bronchopulmonary dysplasia.
- Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men.
- Effects of type IV phosphodiesterase inhibition on cardiac function in the presence and absence of catecholamines.
- Treatment with the type IV phosphodiesterase inhibitor Ro 20-1724 protects renal and mesenteric blood flow in endotoxemic rats treated with norepinephrine.
- Chronic type IV phosphodiesterase inhibition protects glomerular filtration rate and renal and mesenteric blood flow in a zymosan-induced model of multiple organ dysfu...
- Effect of the type IV phosphodiesterase inhibitor Ro 20-1724 on catecholamine-induced alterations in regional vascular resistance and regional blood flow.
- Assessment of the macrophage marker quinolinic acid in cerebrospinal fluid after pediatric traumatic brain injury: insight into the timing and severity of injury in ch...
- Type IV phosphodiesterase inhibition improves cardiac contractility in endotoxemic rats.
- Pro/con clinical debate: do colloids have advantages over crystalloids in paediatric sepsis?
- Safety and efficacy of sedation with propofol for transoesophageal echocardiography in children in an outpatient setting.
- Effect of exogenous surfactant (calfactant) in pediatric acute lung injury: a randomized controlled trial.
- Deletions within a CA-repeat-rich region of intron 4 of the human SP-B gene affect mRNA splicing.
- DNA methylation markers of surfactant proteins in lung cancer.
- Haplotypes of the surfactant protein genes A and D as susceptibility factors for the development of respiratory distress syndrome.
- The use of a daily goals sheet to improve communication in the paediatric intensive care unit.
- Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome.
- Palivizumab in congenital heart disease: should international guidelines be revised?
- Post hoc analysis of calfactant use in immunocompromised children with acute lung injury: Impact and feasibility of further clinical trials.
- An international assessment of a web-based diagnostic tool in critically ill children.
- Validating the genomic signature of pediatric septic shock.
- Palivizumab: a review of its use in the protection of high risk infants against respiratory syncytial virus (RSV).
- Identification of pediatric septic shock subclasses based on genome-wide expression profiling.
- OCTN1 variant L503F is associated with familial and sporadic inflammatory bowel disease.
- Anemia, blood loss, and blood transfusions in North American children in the intensive care unit.
Schools
Temple University
Med University Sc
Chldns Hospital
Doctors Specialties
- Pediatric Critical Care Medicine
- Pediatrics
Accepted Insurances
Awards
- Fellow (FCCM)
- Fellow (FAAP)
Education
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University of Pittsburgh Medical Center -
Medical University of South Carolina -
Temple University School of Medicine
Hospital
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Penn State Milton S. Hershey Medical Center
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