Physician
Anesthesiology
Dr. Nancy T. Colburn, MD
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Nancy T. Colburn, MD is an expert in the field of Anesthesiology. She studied medicine at University of Toledo College of Medicine. Nancy Colburn is also published. She has 101 publications published. The lastest publication: "Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells.'
Publications
- Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies.
- Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region.
- Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression.
- Tricyclic guanidine alkaloids from the marine sponge Acanthella cavernosa that stabilize the tumor suppressor PDCD4.
- Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
- Tumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65.
- Fluorescence endoscopic detection of murine colitis-associated colon cancer by topically applied enzymatically rapid-activatable probe.
- Loss of Sulfiredoxin Renders Mice Resistance to Azoxymethane/Dextran Sulfate Sodium Induced Colon Carcinogenesis.
- An integrated understanding of the physiological response to elevated extracellular phosphate.
- The small molecule NSC676914A is cytotoxic and differentially affects NFκB signaling in ovarian cancer cells and HEK293 cells.
- Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells.
- Community-based team approach to the management of children with cleft palate.
- Drug-induced reversion of progression phenotype is accompanied by reversion of AP-1 phenotype in JB6 cells.
- Progression toward tumor cell phenotype is enhanced by overexpression of a mutant p53 tumor-suppressor gene isolated from nasopharyngeal carcinoma.
- Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
- Phosphorylation status and function of P53 are inversely related to protein kinase C activation.
- The SESL model.
- Developmental disfluency and emerging grammar. II. Co-occurrence of disfluency with specified semantic-syntactic structures.
- Developmental disfluency and emerging grammar. I. Disfluency characteristics in early syntactic utterances.
- p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107.
- No point mutation of Ha-ras or p53 genes expressed in preneoplastic-to-neoplastic progression as modeled in mouse JB6 cell variants.
- Hexose uptake as an indicator of JB6 mouse epidermal cell resistance to the mitogenic activity of TPA.
- Should motorcycles be operated within the legal alcohol limits for automobiles.
- Status of the mdm-2 and waf-1 genes in mouse epidermal jb6 variants harboring wild-type p53 - a p53-independent induction of waf-1.
- Progressive elevation of ap-1 activity during preneoplastic-to-neoplastic progression as modeled in mouse jb6 cell variants.
- Inhibition of tumor promoter induced transformation by expression of the small GTP-binding protein Rac in JB6 cells.
- Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion.
- MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene.
- Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53.
- Serum cytokine concentrations, flavonol intake and colorectal adenoma recurrence in the Polyp Prevention Trial.
- A high-legume low-glycemic index diet reduces fasting plasma leptin in middle-aged insulin-resistant and -sensitive men.
- Depression of catalase gene expression after immortalization and transformation of mouse liver cells.
- Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BA...
- Transfer of phorbol ester promotability by transfection of DNA from promotable into nonpromotable cells.
- Tumor-promoting phorbol esters inhibit procollagen synthesis at a pretranslational level in JB-6 mouse epidermal cells.
- Reduced trisialoganglioside synthesis in chemically but not mos-transformed mouse epidermal cells.
- Role of specific membrane and genetic changes in the mechanism of tumour promotion. Studies with promoter-resistant variants.
- Dosage-dependent dominance over wild-type p53 of a mutant p53 isolated from nasopharyngeal carcinoma.
- Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
- Decreased expression of manganese superoxide dismutase mRNA and protein after immortalization and transformation of mouse liver cells.
- PCR-direct sequencing of a GC-rich region by inclusion of 10% DMSO: application to mouse c-jun.
- Differential transformation efficiency but not AP-1 induction under anchorage-dependent and -independent conditions.
- A family of mitogen-activated protein kinase-related proteins interacts in vivo with activator protein-1 transcription factor.
- Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: one is homologous to human tissue inhibitor...
- Preferential primary-response gene expression in promotion-resistant versus promotion-sensitive JB6 cells.
- c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tu...
- The von Hippel-Lindau (VHL) disease tumor-suppressor gene is not mutated in nasopharyngeal carcinomas.
- Transformation reversion induced in JB6 RT101 cells by AP-1 inhibitors.
- Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter. Specific lack of expression in neoplastic JB6 cells may reflect altered gene meth...
- Sequence and localization of a novel FK506-binding protein to mouse chromosome 11.
- Alterations of the p53 tumor-suppressor gene in transformed mouse liver cells.
- Phorbol ester-induced anchorage independence and its antagonism by retinoic acid correlates with altered expression of specific glycoproteins.
- Responses of preneoplastic epidermal cells to tumor promoters and growth factors: use of promoter-resistant variants for mechanism studies.
- The role of mitogenic stimulation and specific glycoprotein changes in the mechanism of late-stage promotion in JB-6 epidermal cell lines.
- Inhibition by tumor-promoting phorbol esters of procollagen synthesis in promotable JB6 mouse epidermal cells.
- Tumor-promoter-resistant cells lack trisialoganglioside response.
- Ganglioside changes induced by tumor promoters in promotable JB6 mouse epidermal cells: antagonism by an antipromoter.
- Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion.
- Retinoids inhibit promoter-dependent preneoplastic progression in mouse epidermal cell lines.
- Transfer of sensitivity to tumor promoters by transfection of DNA from sensitive into insensitive mouse JB6 epidermal cells.
- Discrimination between nonmalignant and malignant cells by combinations of IFN-gamma and IFN-alpha/beta.
- Membrane and genetic events in tumor promotion: studies with promoter resistant variants of JB6 cells.
- Preferential oxidation of cell surface sialic acid by periodate leads to promotion of transformation in JB6 cells.
- The role of phorbol ester receptor binding in responses to promoters by mouse and human cells.
- Phorbol diester and epidermal growth factor receptors in 12-O-tetradecanoylphorbol-13-acetate-resistant and -sensitive mouse epidermal cells.
- Specific binding of transforming growth factor correlates with promotion of anchorage independence in EGF receptorless mouse JB6 cells.
- Genes and membrane signals involved in neoplastic transformation.
- Benzoyl peroxide promotion of transformation of JB6 mouse epidermal cells: inhibition by ganglioside GT but not retinoic acid.
- Tumor-promoting effects of di(2-ethylhexyl)phthalate in JB6 mouse epidermal cells and mouse skin.
- American Cancer Society workshop on tumor promotion and antipromotion.
- Genes that cooperate with tumor promoters in transformation.
- Lifespan extension of basal cell nevus syndrome fibroblasts by transfection with mouse pro or v-myc genes.
- Protein kinase C and its substrates in tumor promoter-sensitive and -resistant cells.
- Transfer by pro gene transfection of tumor promoter-sensitive phenotype to promotion-insensitive JB6 cells.
- Comparison of P+-active and -inactive pro-1 homologues from human nasopharyngeal carcinoma cells.
- Four-day duration of tumor promoter exposure required to transform JB6 promotion-sensitive cells to anchorage independence.
- Genes and signal transduction in tumor promotion: conclusions from studies with promoter resistant variants of JB-6 mouse epidermal cells.
- Evidence that mouse promotion-sensitivity gene pro1 is transcribed by RNA polymerase III.
- Comparison of mouse pro-1 and pro-2 transfectants for responses to tumor promoters and antipromoters.
- Possible involvement of a lanthanide-sensitive protein kinase C substrate in lanthanide promotion of neoplastic transformation.
- Role of cytoskeleton changes and expression of the H-ras oncogene during promotion of neoplastic transformation in mouse epidermal JB6 cells.
- Extracellular calcium requirement for promotion of transformation in JB6 cells.
- DNA sequences in human nasopharyngeal carcinoma cells that specify susceptibility to tumor promoter-induced neoplastic transformation.
- Induction of anchorage-independent growth of JB6 mouse epidermal cells by 1 alpha,25-dihydroxyvitamin D3.
- Cloning and characterization of putative genes that specify sensitivity to neoplastic transformation by tumor promoters.
- A transforming activity not detected by DNA transfer to NIH 3T3 cells is detected by JB6 mouse epidermal cells.
- Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA.
- Early superoxide dismutase-sensitive event promotes neoplastic transformation in mouse epidermal JB6 cells.
- Differential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB6 cells.
- Transforming activity of nasopharyngeal carcinoma DNA detectable in mouse JB6 cells.
- AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells.
- Synergistic inhibition of phorbol ester-induced transformation of JB6 cells by transforming growth factor-beta and retinoic acid.
- Gene regulation and genetic susceptibility to neoplastic transformation: AP-1 and p80 expression in JB6 cells.
- Isolation and partial characterization of a transformation-associated sequence from human nasopharyngeal carcinoma.
- Deletion mapping of tumor promotion-susceptibility gene pro1 implicates an RNA polymerase III transcription unit.
- An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma.
- Differential induction of 15 and 16 kDa nuclear proteins in promotion sensitive and promotion resistant mouse JB6 cells.
- Differential c-jun expression in response to tumor promoters in JB6 cells sensitive or resistant to neoplastic transformation.
- A simple method using PCR for direct sequencing of genomic DNA from frozen tumor tissue embedded in optimal cutting temperature compound.
- 12-O-tetradecanoylphorbol-13-acetate--induced levels of AP-1 proteins: a 46-kDa protein immunoprecipitated by anti-fra-1 and induced in promotion-resistant but not pro...
Schools
University Of Toledo
University Of Pittsburgh Med Center
Doctors Specialties
- Anesthesiology
Accepted Insurances
Education
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University of Pittsburgh Medical Center -
University of Toledo College of Medicine
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