Professor, Neurosurgery, Yale University School of Medicine
Neurosurgery
Dr. Murat Gunel, MD
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Murat Gunel works in the field of Neurosurgery. He received awards:"CMS Meaningful Use Stage 1 Certification", "Fellow (FAANS)" and "Fellow (FACS)". Murat Gunel is a published physician as well. He has 72 publications published. The latest was: Management of low-grade gliomas: radiation therapy at time of recurrence. Murat Gunel accepts all Medicare patients.
Publications
- Somatic POLE mutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis.
- Exceptional aggressiveness of Cerebral cavernous malformation disease associated with PDCD10 mutations.
- Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK.
- Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors.
- Brain malformations associated with knobloch syndrome-review of literature, expanding clinical spectrum, and identification of novel mutations.
- Seizure control for intracranial arteriovenous malformations is directly related to treatment modality: a meta-analysis.
- NGLY1 mutation causes neuromotor impairment, intellectual disability, and neuropathy.
- Pediatric hepatocellular carcinoma due to somatic CTNNB1 and NFE2L2 mutations in the setting of inherited bi-allelic ABCB11 mutations.
- Commentary: Unruptured Brain Arteriovenous Malformations: What a Tangled Web They Weave.
- Results of a national cerebrovascular neurosurgery survey on the management of Cerebral vasospasm/delayed Cerebral ischemia.
- Homozygous loss of DIAPH1 is a novel cause of microcephaly in humans.
- CLP1 Founder Mutation Links tRNA Splicing and Maturation to Cerebellar Development and Neurodegeneration.
- Ccm3, a gene associated with Cerebral cavernous malformations, is required for neuronal migration.
- Mutations in CSPP1 Lead to Classical Joubert Syndrome.
- Exome sequencing links corticospinal motor neuron Disease to common neurodegenerative disorders.
- Vessel wall magnetic resonance imaging identifies the site of rupture in patients with multiple intracranial Aneurysms: proof of principle.
- Mutations in LAMB1 Cause Cobblestone Brain Malformation without Muscular or Ocular Abnormalities.
- Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 leads to early-onset progressive neurodegeneration.
- Whole-exome sequencing identified a patient with TMCO1 defect syndrome and expands the phenotic spectrum.
- Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO.
- A Step Toward Customizing Radiosurgical Care for Arteriovenous Malformations.
- KRIT1, a gene mutated in Cerebral cavernous malformation, encodes a microtubule-associated protein.
- Epigenetic abNormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype.
- Mutational analysis of 206 families with cavernous malformations.
- ClinicoPathological review: giant intraventricular cavernous malformation.
- The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.
- KRIT1/Cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human Cerebral cortex.
- Krev1 interaction trapped-1/Cerebral cavernous malformation-1 protein expression during early angiogenesis.
- Mapping a Mendelian form of intracranial Aneurysm to 1p34.3-p36.13.
- Tumor necrosis factor alpha is a key modulator of inflammation in cerebral Aneurysms.
- Sequence variants in SLITRK1 are associated with Tourette's syndrome.
- Cerebral venous malformations have distinct genetic origin from Cerebral cavernous malformations.
- Hypertension, age, and location predict rupture of small intracranial Aneurysms.
- Mutations in apoptosis-related gene, PDCD10, cause Cerebral cavernous malformation 3.
- CCM2 expression parallels that of CCM1.
- Molecular genetic analysis of two large kindreds with intracranial Aneurysms demonstrates linkage to 11q24-25 and 14q23-31.
- Cerebrovascular disease associated with Aarskog-Scott syndrome.
- Apparently novel genetic syndrome of pachygyria, mental retardation, seizure, and arachnoid cysts.
- Rapid identification of Disease-causing mutations using copy number analysis within linkage intervals.
- Neurological picture. Complications from cervical intra-arterial heroin injection.
- A novel syndrome of Cerebral cavernous malformation and Greig cephalopolysyndactyly. Laboratory investigation.
- Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders.
- Novel NTRK1 mutations cause hereditary sensory and autonomic neuropathy type IV: demonstration of a founder mutation in the Turkish population.
- PDCD10, the gene mutated in Cerebral cavernous malformation 3, is expressed in the neurovascular unit.
- Apoptotic functions of PDCD10/CCM3, the gene mutated in Cerebral cavernous malformation 3.
- Presence of the Brain proteins cerebral cavernous malformation-2 and cerebral cavernous malformation-3 in rat testes and their potential role in experimental varicocele.
- CCM2 and CCM3 proteins contribute to vasculogenesis and angiogenesis in human placenta.
- A novel heterozygous deletion within the 3'' region of the PAX6 gene causing isolated aniridia in a large family group.
- COL4A1 mutation in preterm intraventricular Hemorrhage.
- The syndrome of pachygyria, mental retardation, and arachnoid cysts maps to 11p15.
- The critical role of hemodynamics in the development of Cerebral vascular disease.
- Novel VLDLR microdeletion identified in two Turkish siblings with pachygyria and pontocerebellar atrophy.
- Four novel SCN1A mutations in Turkish patients with severe myoclonic Epilepsy of infancy (SMEI).
- Temporal expression of angiogenesis-related genes in developing neonatal rodent retina: a novel in vivo model to study Cerebral vascular development.
- A patient with Duchenne muscular dystrophy and autism demonstrates a hemizygous deletion affecting Dystrophin.
- Stabilization of VEGFR2 signaling by Cerebral cavernous malformation 3 is critical for vascular development.
- L-histidine decarboxylase and Tourette's syndrome.
- Genome-wide association study identifies susceptibility loci for IgA nephropathy.
- The essential role of centrosomal NDE1 in human Cerebral cortex neurogenesis.
- CCM2 expression during prenatal development and adult human neocortex.
- Complications from cervical intra-arterial heroin injection.
- Homozygosity mapping and targeted genomic sequencing reveal the gene responsible for cerebellar hypoplasia and quadrupedal locomotion in a consanguineous kindred.
- A founder mutation as a cause of Cerebral cavernous malformation in Hispanic Americans.
- Intraoperative endovascular treatment as an adjunct to microsurgical clipping of paraclinoid Aneurysms.
- Carotid endarterectomy prevention strategies and complications management.
- Vasoactive intestinal polypeptide and its receptor changes in human temporal lobe Epilepsy.
- Heterozygous 5p13.3-13.2 deletion in a patient with type I Chiari malformation and bilateral Duane retraction syndrome.
- Management of low-grade Gliomas: radiation therapy at time of recurrence.
- Sulbactam/ampicillin in the treatment of pediatric infections.
- Azoospermia and cryptorchidism in a male with a de novo reciprocal t(Y;16) translocation.
- SomatiCA: Identifying, Characterizing and Quantifying Somatic Copy Number Aberrations from Cancer Genome Sequencing Data.
Schools
Istanbul Universitesi Cerrahpasa Tip Fakultesi
Yale University School Of Med
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Procedures Preformed
- Cerebrospinal Fluid (CSF) Shunt - Insertion, Repair or Removal
- Craniectomy, Craniotomy, Surgery of Skull Base, Neuroendoscopy
- Lamina Procedures (incl. Laminectomy, Laminoplasty, Laminotomy)
- Repair Intracranial Aneurysm
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Conditions Treated
- Acoustic Neuroma
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- Brain Aneurysm
- Brain Cancer
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Doctors Specialties
- Neurosurgery
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Fellow (FAANS)
- Fellow (FACS)
Education
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Yale-New Haven Hospital -
Istanbul University Faculty of Medicine
Hospital
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Yale-New Haven Hospital
Drug Facts
| NPI NUMBER | 1073594073 | |
| NPPES Provider LastName | GUNEL | |
| NPPES Provider FirstName | MURAT | |
| NPPES Provider ZIPCode | 065191369 | |
| NPPES Provider State | CT | |
| Specialty Description | Neurosurgery | |
| Total Claim Count | 16.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1073594073 |
| Last Name Of The Provider | GUNEL |
| First Name Of The Provider | MURAT |
| View All |
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