Associate Professor Pediatrics at University of California San Francisco Benioff Children's Hospital
Pediatric Hematology & Oncology
Dr. Michelle L. Hermiston, MD
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Michelle Hermiston is an expert in the field of Pediatric Hematology & Oncology. She graduated from Washington University School of Medicine in St. Louis. Michelle L. Hermiston is a published MD. She has 32 publications published. The most current publication "Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene."
Publications
- MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric Leukemia.
- Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) Acute lymphoblastic leukemia.
- Unbiased Modifier Screen Reveals That Signal Strength Determines the Regulatory Role Murine TLR9 Plays in Autoantibody Production.
- A(nother) RAF mutation in LCH.
- The Structural Wedge Domain of the Receptor-like Tyrosine Phosphatase CD45 Enforces B Cell Tolerance by Regulating Substrate Specificity.
- Initially disadvantaged, TEL-AML1 cells expand and initiate Leukemia in response to irradiation and cooperating mutations.
- Oncogenic Kras initiates Leukemia in hematopoietic stem cells.
- Differential impact of the CD45 juxtamembrane wedge on central and peripheral T Cell receptor responses.
- B Cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency.
- Dysregulation of signaling pathways in CD45-deficient NK Cells leads to differentially regulated cytotoxicity and cytokine production.
- The juxtamembrane wedge negatively regulates CD45 function in B Cells.
- CD45: a critical regulator of signaling thresholds in Immune cells.
- A practical approach to the evaluation of the anemic child.
- Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases.
- The genetic basis of early T-cell precursor Acute lymphoblastic leukaemia.
- Donor myocardial infarction impairs the therapeutic potential of bone marrow Cells by an interleukin-1-mediated inflammatory response.
- Requirement for CD45 in fine-tuning mast cell responses mediated by different ligand-receptor Systems.
- PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoImmune background.
- Epstein-Barr virus-associated B cell lymphoproliferative disease in a child with neonatal-onset multiSystem inflammatory disease.
- Use of transgenic mice to infer the biological properties of small intestinal stem Cells and to examine the lineage relationships of their descendants.
- Simultaneous localization of six antigens in single sections of transgenic mouse intestine using a combination of light and fluorescence microscopy.
- CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in Immune cells.
- Phenotype of mice lacking functional Deleted in colorectal Cancer (Dcc) gene.
- Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered Cell migration in the intestinal epithelium.
- Forced expression of E-cadherin in the mouse intestinal epithelium slows Cell migration and provides evidence for nonautonomous regulation of Cell fate in a self-renew...
- Chimeric-transgenic mice represent a powerful tool for studying how the proliferation and differentiation programs of intestinal epithelial Cell lineages are regulated.
- Differentiation and self-renewal in the mouse gastrointestinal epithelium.
- Organization of the crypt-villus axis and evolution of its stem Cell hierarchy during intestinal development.
- In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cel...
- Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin.
- Isolation of mutants defective in early steps of meiotic recombination in the yeast Saccharomyces cerevisiae.
Schools
Washington State University
University Ca Sf School Of Med
Conditions Treated
- Acute Leukemia
- Anemia
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- Brain Cancer
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Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Education
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UCSF -
Washington University School of Medicine in St. Louis
Hospital
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UCSF Medical Center
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