Instructor, Medicine-Massachusetts General Hospital, Harvard Medical School
Oncology
Dr. Michaela J. Higgins, MD
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Michaela Higgins is an expert in the field of Oncology. Michaela J. Higgins is also published. He has 101 publications published. The lastest publication: "The imprinted domain in mouse distal Chromosome 7: reagents for mutagenesis and sequencing.' He is registered with Medicare and accepts Medicare payments.
Publications
- Drug withdrawal in women with progressive metastatic breast Cancer while on aromatase inhibitor therapy.
- Isocitrate Dehydrogenase 1 (IDH1) Mutation in Breast Adenocarcinoma Is Associated With Elevated Levels of Serum and Urine 2-Hydroxyglutarate.
- Planning Cancer control in Latin America and the Caribbean.
- Extended adjuvant endocrine therapy in hormone dependent breast Cancer: The paradigm of the NCIC-CTG MA.17/BIG 1-97 trial.
- Detection of tumor PIK3CA status in Metastatic Breast Cancer using Peripheral Blood.
- Denosumab and the current status of bone-modifying drugs in breast Cancer.
- A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast Cancer.
- Mutation of a single allele of the Cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells.
- Targeted therapies for breast Cancer.
- Pharmacogenetics of endocrine therapy for breast Cancer.
- PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human Breast epithelial cells.
- All nodes lead to chemo...
- CYP2D6 polymorphisms and tamoxifen metabolism: clinical relevance.
- New directions in the systemic treatment of metastatic thyroid Cancer.
- Understanding resistance to tamoxifen in hormone receptor-positive breast Cancer.
- Knockin of mutant PIK3CA activates multiple oncogenic pathways.
- Pharmacogenetics of tamoxifen: who should undergo CYP2D6 genetic testing?
- What is the current status of ovarian suppression/ablation in women with premenopausal early-stage breast Cancer?
- Adjuvant endocrine therapy for premenopausal hormone receptor-positive breast Cancer; much done, more to do.
- Therapeutic options in the management of metastatic breast Cancer.
- Paraneoplastic coma and acquired central alveolar hypoventilation as a manifestation of brainstem encephalitis in a patient with ANNA-1 antibody and small-cell Lung ca...
- Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1.
- Aging skeletal muscle: physiologic changes and the effects of training.
- Placental growth retardation due to loss of imprinting of Phlda2.
- Genetics of multiple Myeloma.
- Expanding role of bisphosphonates in the management of early breast Cancer.
- Chemotherapy for lung Cancer: the state of the art in 2009.
- The androgen receptor in breast Cancer: learning from the past.
- Breast Cancer in 2010: Novel targets and therapies for a personalized approach.
- Silencing of CDKN1C (p57KIP2) is associated with hypomethylation at KvDMR1 in Beckwith-Wiedemann syndrome.
- The imprinted domain in mouse distal Chromosome 7: reagents for mutagenesis and sequencing.
- Alternative mechanisms associated with silencing of CDKN1C in Beckwith-Wiedemann syndrome.
- Divergently transcribed overlapping genes expressed in Liver and kidney and located in the 11p15.5 imprinted domain.
- A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome.
- A model system to study genomic imprinting of human genes.
- Concussive signs and symptoms following head impacts in collegiate athletes.
- The application of atomic force microscopy to topographical studies and force measurements on the secreted adhesive of the green alga Enteromorpha.
- A differentially methylated imprinting control region within the Kcnq1 locus harbors a methylation-sensitive chromatin insulator.
- Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes.
- Epigenotype-phenotype correlations in Beckwith-Wiedemann syndrome.
- Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.
- Mtr1, a novel biallelically expressed gene in the center of the mouse distal chromosome 7 imprinting cluster, is a member of the Trp gene family.
- Knock in of the AKT1 E17K mutation in human Breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.
- Mapping of genes and transcribed sequences in a gene rich 400-kb region on human chromosome 11p15.1-->p14.
- Sex differences in head acceleration during heading while wearing soccer headgear.
- Apolipoprotein E genotype and concussion in college athletes.
- The pericentromeric region of human chromosome 11: evidence for a chromosome-specific duplication.
- Neuronal structural protein polymorphism and concussion in college athletes.
- NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia.
- Increased expression of dendritic mRNA following the inDuction of long-term potentiation.
- Creating conDuctive structures for cell growth: growth and alignment of myogenic cell types on polythiophenes.
- Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation.
- Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromos...
- Contig maps and genomic sequencing identify candidate genes in the usher 1C locus.
- Lacrosse equipment and cervical spinal cord space during immobilization: preliminary Analysis.
- A multiswitchable poly(terthiophene) bearing a spiropyran functionality: understanding photo- and electrochemical control.
- Gender differences in head-neck segment dynamic stabilization during head acceleration.
- Chromosome loops, insulators, and histone methylation: new insights into regulation of imprinting in clusters.
- Electronic health record - public health (EHR-PH) system prototype for interoperability in 21st century healthcare systems.
- Short-term changes in maternal and neonatal urinary iodine excretion.
- Linkage-disequilibrium mapping without genotyping.
- Driven dynamics of the vortex-phase mixture near the peak effect: the "vortex capacitor".
- Percolation transition in the heterogeneous vortex state of NbSe2.
- Pregnancy in women with Type 1 and Type 2 diabetes in Dublin.
- Effect of end-cutting intramedullary reamers on host-allograft contact area.
- Comparison of demographic and donation profiles and transfusion-transmissible disease markers and risk rates in previously transfused and nontransfused blood donors.
- Bipolar affective disorder partially cosegregates with a balanced t(9;11)(p24;q23.1) chromosomal translocation in a Small pedigree.
- Efficacy of the fumagillin Analog TNP-470 for Nucleospora salmonis and Loma salmonae infections in chinook salmon Oncorhynchus tshawytscha.
- Stereology of the placenta in type 1 and type 2 diabetes.
- Structure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in human.
- Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltran...
- Granulomatous appendicitis revisited: report of a case.
- Central nervous system nocardiosis in an immunocompetent child.
- High-throughput genotyping of human platelet antigens using the 5''-nuclease assay and minor groove binder probe technology.
- IMA: An R package for high-throughput Analysis of Illumina's 450K Infinium methylation data.
- Maternal gametic transmission of translocations or inversions of human chromosome 11p15.5 results in regional DNA hypermethylation and downregulation of CDKN1C express...
- Liquid deposition patterning of conDucting polymer ink onto hard and soft flexible substrates via dip-pen nanolithography.
- Fabrication and characterization of cytocompatible polypyrrole films inkjet printed from nanoformulations cytocompatible, inkjet-printed polypyrrole films.
- ConDucting polymers with immobilised fibrillar collagen for enhanced neural interfacing.
- Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells.
- Kynurenine metabolism predicts cognitive function in patients following cardiac bypass and thoracic surgery.
- Genetic variation and individualized medicine.
- Reversible shape memory of nanoscale deformations in inherently conDucting polymers without reprogramming.
- Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome.
- Guidance of neurite outgrowth on aligned electrospun polypyrrole/poly(styrene-beta-isobutylene-beta-styrene) fiber platforms.
- Physical surface and electromechanical properties of doped polypyrrole biomaterials.
- Visualizing dynamic actuation of ultrathin polypyrrole films.
- Identification of DNA methylation in 3' genomic regions that are associated with upregulation of gene expression in colorectal Cancer.
- Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.
- Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.
- Skeletal muscle cell proliferation and differentiation on polypyrrole substrates doped with extracellular matrix components.
- Nanoscale mechanical characterisation of amyloid fibrils discovered in a natural adhesive.
- Frequency modulation atomic force microscopy reveals individual intermediates associated with each unfolded I27 titin domain.
- Integrated medical-psychiatric care of a dying borderline patient: a case of dynamically informed "practical psychotherapy".
- Structured water layers adjacent to biological membranes.
- Autologous blood transfusion for cardiopulmonary bypass: effects of storage conditions on platelet function.
- The role of psychiatry in U.S. Air Force primary care: research-based models for clinical consultation and education.
- Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1.
- Direct imaging of individual intrinsic hydration layers on lipid bilayers at Angstrom resolution.
- Direct imaging of lipid-ion network formation under physiological conditions by frequency modulation atomic force microscopy.
Schools
Tufts Univ Sch Of Med
Procedures Preformed
- Thoracentesis
Conditions Treated
- Adrenal Gland Cancer
- Anal and Rectal Cancer
- Anemia
- Bile Duct Cancer
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Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
- Great West Healthcare-Cigna PPO
- Commercial Insurance Company
- GHI PPO
- Fallon Community Health Plan
- Harvard Pilgrim Health Care PPO
- Medicare MCR
- Network Health
- United Healthcare
Education
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Johns Hopkins University -
University College of Dublin National Univ SOM
Hospital
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Massachusetts General Hospital
Drug Facts
| NPI NUMBER | 1255537973 | |
| NPPES Provider LastName | HIGGINS | |
| NPPES Provider FirstName | MICHAELA | |
| NPPES Provider ZIPCode | 021142621 | |
| NPPES Provider State | MA | |
| Specialty Description | Medical Oncology | |
| Total Claim Count | 249.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1255537973 |
| Last Name Of The Provider | HIGGINS |
| First Name Of The Provider | MICHAELA |
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