Chair, Spine Surgery Division Director, Tissue Engineering/Biomaterials Lab
Orthopaedic Surgery
Dr. Michael J. Yaszemski, MD
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Michael J. Yaszemski, MD is an expert in the field of Orthopaedic Surgery. He went to medical school at Georgetown University School of Medicine. Georgetown University School of Medicine is ranked 49 in research and 84 in primary care medicine Michael Yaszemski is also a published physician. He has 99 publication published. The most recent publication is: Ligament Tissue Engineering Using a Novel Porous Polycaprolactone Fumarate Scaffold and Adipose Tissue-Derived Mesenchymal Stem Cells Grown in Platelet Lysate. He is registered with Medicare.
Publications
- Inhibition of Autophagy Increases 2-Methoxyestradiol-Induced Cytotoxicity in SW1353 Chondrosarcoma Cells.
- Ligament Tissue Engineering Using a Novel Porous Polycaprolactone Fumarate Scaffold and Adipose Tissue-Derived Mesenchymal Stem Cells Grown in Platelet Lysate.
- Tissue Engineered Constructs: Perspectives on Clinical Translation.
- Effect of calcium phosphate coating and rhBMP-2 on bone regeneration in rabbit calvaria using poly(propylene fumarate) scaffolds.
- Nanocomposite bone scaffolds based on biodegradable polymers and hydroxyapatite.
- Specimen-specific nonlinear finite element modeling to predict vertebrae Fracture loads after vertebroplasty.
- Key changes in denervated muscles and their impact on regeneration and reinnervation.
- Comparison of cellular architecture, axonal growth and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord.
- Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma.
- Non-Invasive Isometric Force Measurement of Plantar Flexors in Rats.
- Biomechanical Evaluation of an Injectable and Biodegradable Copolymer P(PF-co-CL) in a Cadaveric Vertebral Body Defect Model.
- Hydrogel-PLGA delivery system prolongs 2-methoxyestradiol-mediated anti-tumor effects in Osteosarcoma cells.
- MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor p53 in Osteosarcoma.
- RNA-Dependent Protein Kinase Is Essential for 2-Methoxyestradiol-Induced Autophagy in Osteosarcoma Cells.
- Evaluation of Osteoconductive Scaffolds in the Canine Femoral Multi-Defect Model.
- Histone deacetylase 3 is required for maintenance of bone mass during aging.
- Delayed repair of the peripheral Nerve: A novel model in the rat sciatic Nerve.
- In vivo transplantation of autogenous marrow-derived cells following rapid intraoperative magnetic separation based on hyaluronan to augment bone regeneration.
- Controlled release of doxorubicin from pH-responsive microgels.
- Fusion of dynactin 1 to anaplastic lymphoma kinase in inflammatory myofibroblastic tumor.
- Short- and long-term peripheral Nerve regeneration using a poly-lactic-co-glycolic-acid scaffold containing Nerve growth factor and glial cell line-derived neurotrophi...
- Controlled release of vascular endothelial growth factor using poly-lactic-co-glycolic acid microspheres: In vitro characterization and application in polycaprolactone...
- Prospective assessment of patient morbidity from prone sacral positioning.
- Reformulating polycaprolactone fumarate to eliminate toxic diethylene glycol: Effects of polymeric branching and autoclave sterilization on material properties.
- Aneurysmal bone cyst of the Cervical spine in children.
- Comparison of polymer scaffolds in rat spinal cord: A step toward quantitative assessment of combinatorial approaches to spinal cord repair.
- High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated ...
- Osteoblast growth and bone-healing response to three-dimensional poly(?-caprolactone fumarate) scaffolds.
- Induction of Fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow.
- Sustained delivery of dibutyryl cyclic adenosine monophosphate to the transected spinal cord via oligo [(polyethylene glycol) fumarate] hydrogels.
- Rat sciatic Nerve repair with a poly-lactic-co-glycolic acid scaffold and Nerve growth factor releasing microspheres.
- COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta.
- In vitro and in vivo release of Nerve growth factor from biodegradable poly-lactic-co-glycolic-acid microspheres.
- Enhanced bone morphogenetic protein-2-induced ectopic and orthotopic bone formation by intermittent parathyroid hormone (1-34) administration.
- Growth factor interactions in bone regeneration.
- Development of Electrically Conductive Oligo(polyethylene glycol) Fumarate-Polypyrrole Hydrogels for Nerve Regeneration.
- Introduction of new devices and technologies into a Spine surgery practice: a review of processes and regulations.
- In vivo biodegradation and biocompatibility of PEG/sebacic acid-based hydrogels using a cage implant system.
- Collagen type I hydrogel allows migration, proliferation, and osteogenic differentiation of rat bone marrow stromal cells.
- Augmentation of surgical angiogenesis in vascularized bone allotransplants with host-derived a/v bundle implantation, fibroblast growth factor-2, and vascular endothel...
- A biofilm approach to detect bacteria on removed spinal implants.
- Video fluoroscopic analysis of the effects of three commonly-prescribed off-the-shelf orthoses on vertebral motion.
- Germline TGF-beta receptor mutations and skeletal fragility: a report on two patients with Loeys-Dietz syndrome.
- 2-methoxyestradiol-mediated anti-tumor effect increases osteoprotegerin expression in Osteosarcoma cells.
- Enhanced cell ingrowth and proliferation through three-dimensional nanocomposite scaffolds with controlled pore structures.
- Porous tantalum and poly-epsilon-caprolactone biocomposites for osteochondral defect repair: preliminary studies in rabbits.
- Metastatic bone Disease: diagnosis, evaluation, and treatment.
- Effects of composite formulation on the mechanical properties of biodegradable poly(propylene fumarate)/bone fiber scaffolds.
- Severe osteogenesis imperfecta in cyclophilin B-deficient mice.
- Three-dimensional porous biodegradable polymeric scaffolds fabricated with biodegradable hydrogel porogens.
- The effects of postoperative ketorolac on wound healing in a rat model.
- Axon regeneration through scaffold into distal spinal cord after transection.
- Mesenchymal stem cells for bone repair and metabolic bone Diseases.
- Importance of the vasculature in cyst formation after spinal cord Injury.
- Development of biodegradable and injectable macromers based on poly(ethylene glycol) and diacid monomers.
- Potential of hydrogels based on poly(ethylene glycol) and sebacic acid as orthopedic tissue engineering scaffolds.
- Solute transport in cyclically deformed porous tissue scaffolds with controlled pore cross-sectional geometries.
- Neural stem cell- and Schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord.
- Neurogenic tumors of the pelvis: clinicopathologic features and surgical outcomes using a multiDisciplinary team.
- Effect of autologous bone marrow stromal cell seeding and bone morphogenetic protein-2 delivery on ectopic bone formation in a microsphere/poly(propylene fumarate) com...
- Designing ideal conduits for peripheral Nerve repair.
- Cellular uptake of gold nanoparticles directly cross-linked with carrier peptides by Osteosarcoma cells.
- Nerve tubes for peripheral Nerve repair.
- Photo-Crosslinked Poly(ε-caprolactone fumarate) Networks: Roles of Crystallinity and Crosslinking Density in Determining Mechanical Properties.
- Rigid fixation of the spinal column improves scaffold alignment and prevents scoliosis in the transected rat spinal cord.
- Urgent surgical decompression compared to methylprednisolone for the treatment of acute spinal cord Injury: a randomized prospective study in beagle dogs.
- 2-methoxyestradiol-induced cell death in Osteosarcoma cells is preceded by cell cycle arrest.
- Fixation strength of unicortical versus bicortical C1-C2 transarticular screws.
- Accuracy of motor axon regeneration across autograft, single-lumen, and multichannel poly(lactic-co-glycolic acid) Nerve tubes.
- Characterization of porous injectable poly-(propylene fumarate)-based bone graft substitute.
- Photo-cross-linked hybrid polymer networks consisting of poly(propylene fumarate) and poly(caprolactone fumarate): controlled physical properties and regulated bone an...
- Relationship of the Internal carotid artery to the anterior aspect of the C1 vertebra: implications for C1-C2 transarticular and C1 lateral mass fixation.
- Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent.
- Methods for in vitro characterization of multichannel Nerve tubes.
- Tissue engineering of bone: material and matrix considerations.
- Synthesis and evaluation of novel biodegradable hydrogels based on poly(ethylene glycol) and sebacic acid as tissue engineering scaffolds.
- Biomechanical evaluation of an injectable radiopaque polypropylene fumarate cement for kyphoplasty in a cadaveric osteoporotic vertebral compression Fracture model.
- Biomechanical comparison of unicortical versus bicortical C1 lateral mass screw fixation.
- Two-dimensional digital video ankle motion analysis for assessment of function in the rat sciatic Nerve model.
- Symposium. The introduction of biologics in orthopaedics: issues of cost, commercialism, and ethics.
- Engineering a noncarrier to a highly efficient carrier peptide for noncovalently delivering biologically active proteins into human cells.
- Changes in red blood cell transfusion practice during the past two decades: a retrospective analysis, with the Mayo database, of adult patients undergoing major Spine ...
- Technology assessment: approach and reimbursement.
- Characterization of photo-cross-linked oligo[poly(ethylene glycol) fumarate] hydrogels for cartilage tissue engineering.
- Total en bloc spondylectomy of C5 vertebra for chordoma.
- C1 anatomy and dimensions relative to lateral mass screw placement.
- Poly(propylene fumarate) bone tissue engineering scaffold fabrication using stereolithography: effects of resin formulations and laser parameters.
- Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of Osteosarcoma cells.
- Local antibiotic delivery with OsteoSet, DBX, and Collagraft.
- Fabrication and characterization of poly(propylene fumarate) scaffolds with controlled pore structures using 3-dimensional printing and injection molding.
- Mechanical effects of partial sacrectomy: when is reconstruction necessary?
- Sacral osteomyelitis after ileal pouch-anal anastomosis: report of four cases.
- Bone-tissue-engineering material poly(propylene fumarate): correlation between molecular weight, chain dimensions, and physical properties.
- Controlled drug release from a novel injectable biodegradable microsphere/scaffold composite based on poly(propylene fumarate).
- Optimal segmentation of microcomputed tomographic images of porous tissue-engineering scaffolds.
- Chondroconductive potential of tantalum trabecular metal.
- Operative management of sacral chordoma.
- Development of a biologic prosthetic composite for cartilage repair.
Schools
Georgetown University School Of Medicine
Wilford Hall Med Center
Harvard Med School
Procedures Preformed
- Dressing and-or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy)
- Dural Repair or Other Spinal Spinal Cord Repair
- Epidural Block, Facet Blocks
- Excision of Femur or Knee
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Conditions Treated
- Ankylosing Spondylitis
- Arm Fracture (incl. Elbow and Shoulder)
- Ataxia
- Back Pain
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Doctors Specialties
- Orthopedic Surgery
- Orthopaedic Surgery
Accepted Insurances
Education
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Beth Israel Deaconess Medical Center -
San Antonio Uniformed Services Health Education Consortium -
Georgetown University School of Medicine
Hospital
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Mayo Clinic - Rochester, Minnesota
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1093792905 |
| Last Name Of The Provider | YASZEMSKI |
| First Name Of The Provider | MICHAEL |
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