Gereral outpatient part-time at Indiana University School of Medicine (Clinical Associate Professor)
Psychiatry
Dr. Michael J. Detke, MD
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Michael J. Detke works in the field of Psychiatry. He attended Perelman School of Medicine at the University of Pennsylvania. Michael Detke is a published physician. He has 66 publications published. The most current publication "Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression." Dr. Michael J. Detke accepts all Medicare patients.
Publications
- Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects.
- Evaluation of the Effects of Duloxetine and Escitalopram on 24-Hour Heart Rate Variability: A Mechanistic Study Using Heart Rate Variability as a Pharmacodynamic Measure.
- Sexual Function during Long-Term Duloxetine Treatment in Patients with Recurrent Major Depressive Disorder.
- Long-term safety, tolerability, and efficacy of duloxetine in the treatment of fibromyalgia.
- Efficacy and safety of duloxetine in patients with chronic low back pain.
- Duloxetine in the prevention of Depressive recurrences: a randomized, double-blind, placebo-controlled trial.
- A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive Disorder after initial duloxetine therapy.
- Efficacy and safety of duloxetine in the treatment of generalized anxiety Disorder: a flexible-dose, progressive-titration, placebo-controlled trial.
- Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive Disorder.
- Duloxetine treatment for role functioning improvement in generalized anxiety Disorder: three independent studies.
- Is PTSD caused by traumatic Stress?
- Simple options for improving signal detection in antidepressant clinical trials.
- Efficacy of Duloxetine for the Treatment of Generalized Anxiety Disorder: Implications for Primary Care Physicians.
- The Safety and Tolerability of Duloxetine Compared With Paroxetine and Placebo: A Pooled Analysis of 4 Clinical Trials.
- Duloxetine for the treatment of major depressive Disorder in women ages 40 to 55 years.
- Sexual functioning assessed in 4 double-blind placebo- and paroxetine-controlled trials of duloxetine for major depressive Disorder.
- Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine.
- Duloxetine for the treatment of major depressive Disorder in older patients.
- Time course of depression-symptom improvement during treatment with duloxetine.
- A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive Disorder.
- Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine.
- The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates?
- Effects of duloxetine on painful physical symptoms associated with depression.
- Urinary Side Effects of Duloxetine in the Treatment of Depression and Stress Urinary Incontinence.
- Duloxetine: A New Treatment for the Emotional and Physical Symptoms of Depression.
- Duloxetine in treatment of Anxiety symptoms associated with depression.
- Antidepressant-like effects of cytidine in the forced swim test in rats.
- The tyramine pressor test may have limited sensitivity, especially in the presence of dual serotonin/norepinephrine uptake inhibition.
- Duloxetine, 60 mg once daily, for major depressive Disorder: a randomized double-blind placebo-controlled trial.
- Duloxetine for the treatment of major depressive Disorder.
- A double-blind, randomized trial of duloxetine versus placebo in the management of chronic low back pain.
- A non-inferiority comparison of duloxetine and venlafaxine in the treatment of adult patients with generalized anxiety Disorder.
- Patterns of Depressive symptom response in duloxetine-treated outpatients with mild, moderate or more severe depression.
- Duloxetine in the treatment of major depressive Disorder: a placebo- and paroxetine-controlled trial.
- Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test.
- Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression.
- Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth.
- Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants.
- Blockade of the antidepressant-like effects of 8-OH-DPAT, buspirone and desipramine in the rat forced swim test by 5HT1A receptor antagonists.
- Modulation of behavioral and insulin responses by contextual stimuli paired with food.
- Placebo response and antidepressant clinical trial outcome.
- Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of Major depression.
- The efficacy of duloxetine: a comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials.
- Duloxetine vs. placebo in patients with painful diabetic neuropathy.
- The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression.
- Onset of action for duloxetine 60 mg once daily: double-blind, placebo-controlled studies.
- Duloxetine in the acute and long-term treatment of major depressive Disorder: a placebo- and paroxetine-controlled trial.
- Is treatment-associated hypomania rare with duloxetine: secondary analysis of controlled trials in non-Bipolar depression.
- Management of depression relapse: re-initiation of duloxetine treatment or dose increase.
- Duloxetine in the prevention of relapse of major depressive Disorder: double-blind placebo-controlled study.
- Comparing onset of antidepressant action using a repeated measures approach and a traditional assessment schedule.
- A case study comparing a randomized withdrawal trial and a double-blind long-term trial for assessing the long-term efficacy of an antidepressant.
- Duloxetine as an SNRI treatment for generalized anxiety Disorder: results from a placebo and active-controlled trial.
- Duloxetine treatment for relapse prevention in adults with generalized anxiety Disorder: a double-blind placebo-controlled trial.
- Clinical evidence for serotonin and norepinephrine reuptake inhibition of duloxetine.
- Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive Disorder: Results from a 6-month, randomized, double-blind...
- Examining quality of life in patients with generalized anxiety Disorder: clinical relevance and response to duloxetine treatment.
- Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram).
- The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with majo...
- Use of effect size to determine optimal dose of duloxetine in major depressive Disorder.
- Evidence for the efficacy of duloxetine in trEating mild, moderate, and severe depression.
- Duloxetine in the treatment of major depressive Disorder: an open-label study.
- A six-month double-blind, placebo-controlled, randomized clinical trial of duloxetine for the treatment of fibromyalgia.
- Evaluating the maintenance of effect of duloxetine in patients with diabetic peripheral neuropathic pain.
- Long-term safety of duloxetine during open-label compassionate use treatment of patients who completed previous duloxetine clinical trials.
Schools
Perelman School of Medicine University of Pennsylvania
Mass Gen Hospital
Conditions Treated
- Adjustment Disorder
- Anxiety
- Bipolar Disorder
- Borderline Personality Disorder
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Doctors Specialties
- Psychiatry
Accepted Insurances
Education
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Massachusetts General Hospital -
University of Pennsylvania -
Perelman School of Medicine at the University of Pennsylvania
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1275570558 |
| Last Name Of The Provider | DETKE |
| First Name Of The Provider | MICHAEL |
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