Chief, Infectious Diseases; Professor, Medicine, UCLA School of Medicine
Infectious Disease
Dr. Michael A. Lovett, MD
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Michael A. Lovett works in the field of Infectious Disease. He graduated from University of California San Diego School of Medicine. University of California San Diego School of Medicine has a rank of 17 in research and a 19 in primary care Dr. Michael A. Lovett is a published doctor. He has 84 papers published. The most current publication "Isolation and characterization of the outer membrane of Borrelia hermsii."
Publications
- Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection.
- The transcriptome of utricle hair cell regeneration in the avian inner ear.
- Prolonged leptospira urinary shedding in a 10-year-old girl.
- Characterization of the outer membrane proteome of Leptospira interrogans expressed during acute lethal infection.
- Lethal infection of C3H/HeJ and C3H/SCID mice with an isolate of Leptospira interrogans serovar copenhageni.
- Quantitative assessment of protection in experimental syphilis.
- Changes in lipopolysaccharide O antigen distinguish acute versus chronic Leptospira interrogans infections.
- A monoclonal antibody that conveys in vitro killing and partial protection in experimental syphilis binds a phosphorylcholine surface epitope of Treponema pallidum.
- Temporal analysis of the antigenic composition of Borrelia burgdorferi during infection in rabbit skin.
- Alveolar septal deposition of immunoglobulin and complement parallels pulmonary hemorrhage in a guinea pig model of severe pulmonary leptospirosis.
- Ocular vaccinia following exposure to a smallpox vaccinee.
- Antigenic composition of Borrelia burgdorferi during infection of SCID mice.
- Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea.
- Isolation of cDNAs from the Cri-du-chat critical region by direct screening of a chromosome 5-specific cDNA library.
- Presenilin 1 interaction in the brain with a novel member of the Armadillo family.
- Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval.
- Physical map of the chromosome 6q22 region containing the oculodentodigital dysplasia locus: analysis of thirteen candidate genes and identification of novel ESTs and ...
- The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes.
- Identification of the homologous beige and Chediak-Higashi syndrome genes.
- Gene expression in pharyngeal arch 1 during human embryonic development.
- Serologic analysis of first-episode nonprimary genital herpes simplex virus infection. Presence of type 2 antibody in acute serum samples.
- Identification of direct downstream targets of Dlx5 during early inner ear development.
- Applying genomics to the avian inner ear: development of subtractive cDNA resources for exploring sensory function and hair cell regeneration.
- Survival of Borrelia burgdorferi in different electroporation buffers.
- Expression of Treponema pallidum antigens in Escherichia coli.
- Serodiagnosis of syphilis by enzyme-linked immunosorbent assay with purified recombinant Treponema pallidum antigen 4D.
- Radiation hybrid map of 13 loci on the long arm of chromosome 5.
- Molecular cloning of the major outer membrane protein of Chlamydia trachomatis.
- Chemotaxis in Borrelia burgdorferi.
- Interjunctional invasion of endothelial cell monolayers.
- Properties of an ordered ring structure formed by recombinant Treponema pallidum surface antigen 4D.
- Role of disulfide bonds in the oligomeric structure and protease resistance of recombinant and native Treponema pallidum surface antigen 4D.
- Virulent strain associated outer membrane proteins of Borrelia burgdorferi.
- Use of the "blue halo" assay in the identification of genes encoding exported proteins with cleavable signal peptides: cloning of a Borrelia burgdorferi plasmid gene w...
- Purification of Treponema pallidum, Nichols strain, by Percoll density gradient centrifugation.
- Analysis of outer membrane ultrastructure of pathogenic Treponema and Borrelia species by freeze-fracture electron microscopy.
- Molecular characterization of common treponemal antigens.
- Interactions of Treponema pallidum with endothelial cell monolayers.
- Correlation of treponemicidal activity in normal human serum with the presence of IgG antibody directed against polypeptides of Treponema phagedenis biotype Reiter and...
- Identification of Treponema pallidum subspecies pallidum genes encoding signal peptides and membrane-spanning sequences using a novel alkaline phosphatase expression v...
- Demonstration of rare protein in the outer membrane of Treponema pallidum subsp. pallidum by freeze-fracture analysis.
- The antigenic interrelationship between the endoflagella of Treponema phagedenis biotype Reiter and Treponema pallidum Nichols strain. I. Treponemicidal activity of cr...
- Humoral immune response in human syphilis to polypeptides of Treponema pallidum.
- Humoral immune response in experimental syphilis to polypeptides of Treponema pallidum.
- The Oms66 (p66) protein is a Borrelia burgdorferi porin.
- Treponema pallidum invades intercellular junctions of endothelial cell monolayers.
- Porin activity of the native and recombinant outer membrane protein Oms28 of Borrelia burgdorferi.
- Identification of Treponema pallidum penicillin-binding proteins.
- Surface antigens of the syphilis spirochete and their potential as virulence determinants.
- Porin activity and sequence analysis of a 31-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp1).
- Antigenic interrelationship between endoflagella of Treponema phagedenis biotype Reiter and Treponema pallidum (Nichols): molecular characterization of endoflagellar p...
- Isolation of the outer membranes from Treponema pallidum and Treponema vincentii.
- Renaturation of recombinant Treponema pallidum rare outer membrane protein 1 into a trimeric, hydrophobic, and porin-active conformation.
- A 9.0-kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein: evidence for expression only during infection.
- The surface of virulent Treponema pallidum: resistance to antibody binding in the absence of complement and surface association of recombinant antigen 4D.
- Selective release of the Treponema pallidum outer membrane and associated polypeptides with Triton X-114.
- Cloning and molecular characterization of plasmid-encoded antigens of Borrelia burgdorferi.
- Sequence analysis and characterization of a 40-kilodalton Borrelia hermsii glycerophosphodiester phosphodiesterase homolog.
- Complement activation limits the rate of in vitro treponemicidal activity and correlates with antibody-mediated aggregation of Treponema pallidum rare outer membrane p...
- Native surface association of a recombinant 38-kilodalton Treponema pallidum antigen isolated from the Escherichia coli outer membrane.
- Purification and characterization of a cloned protease-resistant Treponema pallidum-specific antigen.
- Immunization with Treponema pallidum outer membrane vesicles induces high-titer complement-dependent treponemicidal activity and aggregation of T. pallidum rare outer ...
- Demonstration by mass spectrometry that purified native Treponema pallidum rare outer membrane protein 1 (Tromp1) has a cleaved signal peptide.
- Rabbit model of Lyme borreliosis: erythema migrans, infection-derived immunity, and identification of Borrelia burgdorferi proteins associated with virulence and prote...
- Changes in the surface of Leptospira interrogans serovar grippotyphosa during in vitro cultivation.
- Treponemicidal antibody measured by the "washed-killing" assay correlates with immunity in experimental rabbit syphilis.
- Acquired resistance to Borrelia burgdorferi infection in the rabbit. Comparison between outer surface protein A vaccine- and infection-derived immunity.
- Recombinant Treponema pallidum rare outer membrane protein 1 (Tromp1) expressed in Escherichia coli has porin activity and surface antigenic exposure.
- Sequence analysis and recombinant expression of a 28-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp2).
- Molecular cloning and sequence analysis of the gene encoding OmpL1, a transmembrane outer membrane protein of pathogenic Leptospira spp.
- Immunization of rabbits with recombinant Treponema pallidum surface antigen 4D alters the course of experimental syphilis.
- Cloning, sequencing, and expression of two class B endoflagellar genes of Treponema pallidum subsp. pallidum encoding the 34.5- and 31.0-kilodalton proteins.
- Protection elicited by native outer membrane protein Oms66 (p66) against host-adapted Borrelia burgdorferi: conformational nature of bactericidal epitopes.
- Immunohistochemical analysis of Lyme disease in the skin of naive and infection-immune rabbits following challenge.
- Antigenic and structural characterization of Treponema pallidum (Nichols strain) endoflagella.
- Immunization with Treponema pallidum endoflagella alters the course of experimental rabbit syphilis.
- Homologous and heterologous Borrelia burgdorferi challenge of infection-derived immune rabbits using host-adapted organisms.
- Comparison of protection in rabbits against host-adapted and cultivated Borrelia burgdorferi following infection-derived immunity or immunization with outer membrane v...
- Correlation of immunity in experimental syphilis with serum-mediated aggregation of Treponema pallidum rare outer membrane proteins.
- Isolation and characterization of the outer membrane of Borrelia hermsii.
- Leptospirosis: a zoonotic disease of global importance.
- Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni.
- Use of the skin protection assay in experimental syphilis to assess protective immunity against a specific Treponema pallidum surface epitope.
Schools
University Of California San Diego School Of Medicine
Mass Gen Hospital
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Education
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Massachusetts General Hospital -
University of California San Diego School of Medicine
Hospital
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Ronald Reagan UCLA Medical Center
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