Professor of Medicine, Brigham and Women's Hospital
Gastroenterology
Dr. Martin C. Carey, MD
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Doctor Martin C. Carey, MD is an expert in the field of Gastroenterology. He over the years received 3 awards: "Fellow (AGAF)", "Elected Member" and "Whos Who in Medicine and Healthcare". Dr. Martin C. Carey is a published doctor. He has 101 publications published. The most current publication "Laser light scattering evidence for a common wormlike growth structure of mixed micelles in bile salt- and straight-chain detergent-phosphatidylcholine aqueous systems..." Martin Carey is registered with Medicare and accepts Medicare payments.
Publications
- Influence of Phosphatidylcholine and Calcium on Self-Association and Bile Salt Mixed Micellar Binding of the Natural Bile Pigment, Bilirubin Ditaurate.
- Self-assembly of aqueous bilirubin ditaurate, a natural conjugated bile pigment, to contraposing enantiomeric dimers and m(-) and p(+) tetramers and their selective hy...
- Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice.
- Metastable and equilibrium phase diagrams of unconjugated bilirubin IXα as functions of pH in model bile systems: Implications for pigment gallstone formation.
- New pathophysiological concepts underlying pathogenesis of pigment gallstones.
- Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice.
- Pathophysiological preconditions promoting mixed "black" pigment plus cholesterol gallstones in a DeltaF508 mouse model of cystic fibrosis.
- Biliary lipids and cholesterol gallstone disease.
- Roles of infection, inflammation, and the immune system in cholesterol gallstone formation.
- Hepatic insulin resistance directly promotes formation of cholesterol gallstones.
- Pathophysiological basis of liver disease in cystic fibrosis employing a DeltaF508 mouse model.
- Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.
- T-cell function is critical for murine cholesterol gallstone formation.
- Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8(-/-) mice.
- QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains.
- Helicobacter pylori and cholesterol gallstone formation in C57L/J mice: a prospective study.
- Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice.
- Identification of cholelithogenic enterohepatic helicobacter species and their role in murine cholesterol gallstone formation.
- Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance.
- Single and interacting QTLs for cholesterol gallstones revealed in an intercross between mouse strains NZB and SM.
- Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis.
- Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice.
- Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice.
- Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis.
- Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse.
- Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains.
- FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice.
- New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice.
- Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis.
- Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice.
- Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct ve...
- Lith genes control mucin accumulation, cholesterol crystallization, and gallstone formation in A/J and AKR/J inbred mice.
- Epidemiology of the American Indians' burden and its likely genetic origins.
- Biliary cholesterol secretion by the twinned sterol half-transporters ABCG5 and ABCG8.
- Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk.
- Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers.
- Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice.
- Cholesterol synthesis inhibition distal to squalene upregulates biliary phospholipid secretion and counteracts cholelithiasis in the genetically prone C57L/J mouse.
- Characterization of crystallization pathways during cholesterol precipitation from human gallbladder biles: identical pathways to corresponding model biles with three ...
- Physical chemistry of biliary lipids during bile formation.
- Cholesterol carriers in human bile: are "lamellae" involved?
- Rapid (1 hour) high performance gel filtration chromatography resolves coexisting simple micelles, mixed micelles, and vesicles in bile.
- Calcium affinity for biliary lipid aggregates in model biles: complementary importance of bile salts and lecithin.
- Pan-sulfation of bile salts markedly increases hydrophilicity and essentially abolishes self- and hetero-association with lecithin.
- The gene encoding the multispecific organic anion transporter (Cmoat) of the hepatocyte canalicular membrane maps to mouse chromosome 19.
- Enterohepatic cycling of bilirubin: a putative mechanism for pigment gallstone formation in ileal Crohn's disease.
- Spread monomolecular films of monohydroxy bile acids and their salts: influence of hydroxyl position, bulk pH, and association with phosphatidylcholine.
- Pathophysiology and pathogenesis of cholesterol gallstone formation.
- Formation of mixed micelles and vesicles of human apolipoproteins A-I and A-II with synthetic and natural lecithins and the bile salt sodium taurocholate: quasi-elasti...
- Fluorocholesterols, in contrast to hydroxycholesterols, exhibit interfacial properties similar to cholesterol.
- Molecular species of lecithins in human gallbladder bile.
- Evidence for an ATP-independent long-chain phosphatidylcholine translocator in hepatocyte membranes.
- Physical-chemical basis of gallstone formation.
- Laser light scattering evidence for a common wormlike growth structure of mixed micelles in bile salt- and straight-chain detergent-phosphatidylcholine aqueous systems...
- Principles of laser light-scattering spectroscopy: applications to the physicochemical study of model and native biles.
- Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: relevance to bile formation and stability.
- Whither biliary sludge?
- Chemical species of lipids in bile.
- Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones.
- In vitro evidence that phospholipid secretion into bile may be coordinated intracellularly by the combined actions of bile salts and the specific phosphatidylcholine t...
- Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems pa...
- Quasielastic light scattering evidence for vesicular secretion of biliary lipids.
- Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during ...
- Bile salt hydrophobicity controls vesicle secretion rates and transformations in native bile.
- Enterohepatic cycling of bilirubin as a cause of ''black'' pigment gallstones in adult life.
- Cryoelectron microscopy of a nucleating model bile in vitreous ice: formation of primordial vesicles.
- Biliary lipid secretion in health and in cholesterol gallstone disease.
- The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man.
- Bilirubin cycles enterohepatically after ileal resection in the rat.
- Cholesterol gallstone formation. 1. Physical-chemistry of bile and biliary lipid secretion.
- Thermodynamic and molecular determinants of sterol solubilities in bile salt micelles.
- Cholesterol gallstone dissolution in bile. Dissolution kinetics of crystalline cholesterol monohydrate by conjugated chenodeoxycholate-lecithin and conjugated ursodeox...
- Dissolution of human cholesterol gallstones in stimulated chenodeoxycholate-rich and ursodeoxycholate-rich biles. An in vitro study of dissolution rates and mechanisms.
- Cholesterol gallstone formation. 2. Pathobiology and pathomechanics.
- Apolipoprotein E4: another risk factor for cholesterol gallstone formation?
- Pathogenesis of cholesterol gallstones: a parsimonious hypothesis.
- Cholesterol gallstone dissolution in bile: dissolution kinetics of crystalline (anhydrate and monohydrate) cholesterol with chenodeoxycholate, ursodeoxycholate, and th...
- The "mirroring" of gallstones: description of a novel silvering method to determine the surface area of an irregular object. In vitro demonstration that multiple galls...
- The hydrophobic-hydrophilic balance of bile salts. Inverse correlation between reverse-phase high performance liquid chromatographic mobilities and micellar cholestero...
- Self-association of human apolipoproteins A-I and A-II and interactions of apolipoprotein A-I with bile salts: quasi-elastic light scattering studies.
- Mathematical model of biliary lipid secretion: a quantitative analysis of physiological and biochemical data from man and other species.
- Imaging biliary lipid secretion in the rat: ultrastructural evidence for vesiculation of the hepatocyte canalicular membrane.
- Microscope laser light-scattering spectroscopy of vesicles within canaliculi of rat hepatocyte couplets.
- Influence of dilution on the physical state of model bile systems: NMR and quasi-elastic light-scattering investigations.
- Effects of taurodihydrofusidate, a bile salt analogue, on bile formation and biliary lipid secretion in the rhesus monkey.
- Update on physical state of bile.
- Critical tables for calculating the cholesterol saturation of native bile.
- Pathogenesis of gallstones.
- Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores.
- Rapid computation with the personal computer of the percent cholesterol saturation of bile samples.
- Effects of bile and bile salts on growth and membrane lipid uptake by Giardia lamblia. Possible implications for pathogenesis of intestinal disease.
- Micellar properties of sodium fusidate, a steroid antibiotic structurally resembling the bile salts.
- Homing-in on the origin of biliary steroids.
- Aspirin prevention of cholesterol gallstone formation in prairie dogs.
- Bile acids and bile salts: ionization and solubility properties.
- Coassimilation of dietary fat and benzo(a)pyrene in the small intestine: an absorption model using the killifish.
- Physical-chemical pathogenesis of pigment gallstones.
- Aqueous bile salt-lecithin-cholesterol systems: equilibrium aspects.
- Physical-chemical methods for determining bilirubin solubilities in simulated bile systems.
- Quasi-elastic light-scattering studies of aqueous biliary lipid systems. Cholesterol solubilization and precipitation in model bile solutions.
Doctors Specialties
- Gastroenterology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- First Health (Coventry Health Care) PPO
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Awards
- Fellow (AGAF)
- Elected Member
- Whos Who in Medicine and Healthcare
Education
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Boston University Medical Center -
University College of Dublin National Univ SOM
Hospital
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Brigham and Women's Hospital
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