Assistant Professor of Pediatrics, Boston Children's Hospital

Nephrology

Markus Frank works in the field of Nephrology. He studied medicine at Albert Einstein College of Medicine. He has 1 awards "Elected Member". Markus Frank is also a published MD. He has 25 publication published. The most recent publication is: ABCB5-targeted chemoresistance reversal inhibits Merkel cell carcinoma growth.

Publications

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• ABCB5-targeted chemoresistance reversal inhibits Merkel cell carcinoma growth.
• Nestin depletion induces melanoma matrix metalloproteinases and invasion.
• ABCB5 is a limbal stem cell gene required for corneal development and repair.
• Stem cells and targeted approaches to melanoma cure.
• Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk.
• Synergy of photoacoustic and fluorescence flow cytometry of circulating cells with negative and positive contrasts.
• Metabolic Inhibition of Galectin-1-Binding Carbohydrates Accentuates Antitumor Immunity.
• ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients.
• The Pro-Apoptotic Protein Bim Is a MicroRNA Target in Kidney Progenitors.
• Colorectal Cancer Stem Cells: Biology and Therapeutic Implications.
• VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth.
• Isolation of tumorigenic circulating melanoma cells.
• The in vitro spheroid melanoma cell culture assay: cues on tumor initiation?
• A novel in vivo regulatory role of P-glycoprotein in alloimmunity.
• Modulation of T-cell activation by malignant melanoma initiating cells.
• The therapeutic promise of the cancer stem cell concept.
• Identification and targeting of cancer stem cells.
• Antitumor immunity and cancer stem cells.
• Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.
• ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma.
• CD40-induced transcriptional activation of vascular endothelial growth factor involves a 68-bp region of the promoter containing a CpG island.
• Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter.
• P-glycoprotein and alloimmune T-cell activation.
• Restoring the cornea from limbal stem cells.

Schools

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• RuprechtKarlsUniversitaet Heidelberg Medizinische Gesamtfakultat

• Albert Einstein College Of Med

• Albert Einstein College Med

• Brigham and Womens Hospital Harvard Med School

• Harvard Med School

Doctors Specialties

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• Internal Medicine
• Nephrology

Accepted Insurances

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Awards

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• Elected Member

Education

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• Brigham and Women's Hospital
• Albert Einstein College of Medicine
• Ruprecht Karl University Faculty of Medicine

Hospital

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• Boston Children's Hospital
• Brigham and Women's Hospital

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