Professor, Medicine, University of Pittsburgh School of Medicine
Internal Medicine
Dr. Mark T. Gladwin, MD
|
|
Give Review
Mark Gladwin practices Internal Medicine. He graduated from University of Miami Miller School of Medicine. University of Miami Miller School of Medicine has a rank of 45 in research and a 0 in primary care He received awards:"CMS Meaningful Use Stage 1 Certification" and "Elected Member". Mark Gladwin is a published MD as well. He has 100 publications published. The latest was: Noninfectious and Nonneoplastic Conditions Associated with Human Immunodeficiency Virus Infection. He is registered with Medicare and accepts Medicare payments.
Publications
- Noninfectious and Nonneoplastic Conditions Associated with Human Immunodeficiency Virus Infection.
- SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With ...
- Increased consumption and vasodilatory effect of nitrite during exercise.
- Crises in Sickle Cell Disease.
- Shining a Light on Carbon Monoxide Poisoning.
- Strategies to increase nitric oxide signalling in cardiovascular Disease.
- Effects of Aged Stored Autologous Red Blood Cells on Human Endothelial Function.
- Traffic Light: prognosis-based eligibility for clinical trials of hematopoietic SCT in adults with sickle cell anemia.
- Vasculopathy and Pulmonary hypertension in sickle cell disease.
- Management of patients with sickle cell Disease.
- Exploring the mechanisms of the reductase activity of neuroglobin by site-directed mutagenesis of the heme distal pocket.
- Mechanisms of human erythrocytic bioactivation of nitrite.
- Nitrite modulates bacterial antibiotic susceptibility and biofilm formation in association with airway epithelial cells.
- Harnessing the Nitrate-Nitrite-NO Pathway for Therapy of Heart Failure with Preserved Ejection Fraction.
- Nox2-dependent glutathionylation of endothelial NOS leads to uncoupled superoxide production and endothelial barrier dysfunction in acute Lung injury.
- The genetics of hemoglobin A2 regulation in sickle cell anemia.
- Pulmonary hypertension in sickle cell disease.
- Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects.
- Towards microfluidic-based depletion of stiff and fragile human red cells that accumulate during blood storage.
- Training Pulmonary Researchers to Span the Bench-to-Bedside "Valley of Death".
- Pitfalls in measuring NO bioavailability using NOx.
- Sulfite oxidase catalyzes single electron transfer at molybdenum domain to reduce nitrite to nitric oxide.
- Reply: Practice Guideline for Pulmonary Hypertension in Sickle Cell: Direct Evidence Needed before Universal Adoption.
- Isolated right ventricular dysfunction in patients with human immunodeficiency virus.
- Computed tomography correlates with cardioPulmonary hemodynamics in Pulmonary hypertension in adults with sickle cell disease.
- Nitrite Reductase and Nitric-oxide Synthase Activity of the Mitochondrial Molybdopterin Enzymes mARC1 and mARC2.
- Pulmonary Hypertension: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.
- Abnormal Pulmonary function and associated risk factors in children and adolescents with sickle cell anemia.
- Mechanisms of nitrite bioactivation.
- Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of Pneumonia.
- An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe Asthma.
- Fatty Acid Nitroalkenes Ameliorate Glucose Intolerance and Pulmonary Hypertension in High Fat Diet-Induced Obesity.
- A pilot study of electronic directly observed therapy to improve hydroxyurea adherence in pediatric patients with sickle-cell Disease.
- First successful lung transplantation for sickle cell disease with severe Pulmonary arterial hypertension and Pulmonary veno-occlusive disease.
- Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe Pulmonary arterial hypertension.
- Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine Pneumonia.
- Haemoglobinuria is associated with Chronic kidney disease and its progression in patients with sickle cell anaemia.
- Differences in the clinical and genotypic presentation of sickle cell Disease around the world.
- Evidence mounts that red cells and deoxyhemoglobin can reduce nitrite to bioactive NO to mediate intravascular endocrine NO signaling: commentary on "Anti-platelet eff...
- Unraveling restrictive Chronic lung disease in sickle cell disease [Editorial].
- Nitric oxide scavenging by red cell microparticles.
- Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling.
- Direct sGC activation bypasses NO scavenging reactions of intravascular free oxy-hemoglobin and limits vasoconstriction.
- Nitrite signaling in Pulmonary hypertension: mechanisms of bioactivation, signaling, and therapeutics.
- Red blood cell endothelial nitric oxide synthase does not modulate red blood cell storage hemolysis.
- Clinical correlates of acute Pulmonary events in children and adolescents with sickle cell disease.
- Mechanisms for cellular NO oxidation and nitrite formation in Lung epithelial cells.
- Nebulized nitrite protects rat Lung grafts from ischemia reperfusion injury.
- The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe.
- In vivo reduction of cell-free methemoglobin to oxyhemoglobin results in vasoconstriction in canines.
- Physiologic Changes in a Nonhuman Primate Model of HIV-Associated Pulmonary Arterial Hypertension.
- Mortality increases after massive exchange transfusion with older stored blood in canines with experimental Pneumonia.
- Genetic determinants of haemolysis in sickle cell anaemia.
- Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin.
- Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia.
- CardioPulmonary function in individuals with HIV infection in the antiretroviral therapy era.
- 14-3-3 binding and phosphorylation of neuroglobin during hypoxia modulates the six-to-five heme pocket coordination and the rate of nitrite reduction to nitric oxide.
- Mechanisms of slower nitric oxide uptake by red blood cells and other hemoglobin-containing vesicle.
- Endothelial Chronic Destructive Pulmonary Disease (E-CDPD): Is Endothelial Apoptosis a Subphenotype or Prequel to COPD?
- Nitric Oxide Scavenging by Red Blood Cell Microparticles and Cell-Free Hemoglobin as a Mechanism for the Red Cell Storage Lesion.
- Senicapoc trial results support the existence of different sub-phenotypes of sickle cell Disease with possible drug-induced phenotypic shifts.
- NT-pro brain natriuretic peptide levels and the risk of death in the cooperative study of sickle cell Disease.
- Ancestry of African Americans with sickle cell Disease.
- Oxidases and peroxidases in cardiovascular and lung Disease: New concepts in reactive oxygen species signaling.
- Methaemalbumin formation in sickle cell Disease: effect on oxidative protein modification and HO-1 induction.
- Human Neuroglobin Functions as a Redox-regulated Nitrite Reductase.
- Predictors of osteoclast activity in sickle cell Disease patients.
- Hospitalization for pain in patients with sickle cell Disease treated with sildenafil for elevated TRV and low exercise capacity.
- Storage lesion: role of red blood cell breakdown.
- Nitrite-generated NO circumvents dysregulated arginine/NOS signaling to protect against intimal hyperplasia in Sprague-Dawley rats.
- Pulmonary vascular lesions are common in SIV- and SHIV-env-infected macaques.
- Adenosine receptor crossroads in sickle cell Disease.
- Elevated N-Terminal Pro-Brain Natriuretic Peptide Is Associated with Mortality in Tobacco Smokers Independent of Airflow Obstruction.
- Nitrite-NO bailout for a NOS complex too big to fail.
- Strategic plan for Lung vascular research: An NHLBI-ORDR Workshop Report.
- Characterization of erythrocytic uptake and release and disposition pathways of nitrite, nitrate, methemoglobin, and iron-nitrosyl hemoglobin in the human circulation.
- Arginine metabolism and nitric oxide bioavailability in sickle cell Disease.
- Perivascular T Cell Infiltration Leads to Sustained Pulmonary Artery Remodeling After Endothelial Cell Damage.
- Increased Pulmonary pressures and myocardial wall stress in children with severe malaria.
- Pulmonary hypertension and NO in sickle cell.
- Hydroxyurea-induced expression of glutathione peroxidase 1 in red blood cells of individuals with sickle cell anemia.
- Pulmonary hypertension in hemolytic disorders: Pulmonary vascular disease: the global perspective.
- Update on Pulmonary hypertension 2009.
- Bad blood: the risks of red cell storage.
- Segmentation and quantification of Pulmonary artery for noninvasive CT assessment of sickle cell secondary Pulmonary hypertension.
- An electron paramagnetic resonance study of the affinity of nitrite for methemoglobin.
- Hemodialysis hyperhemolysis. A novel mechanism of endothelial dysfunction and cardiovascular risk?
- Nitrite potently inhibits hypoxic and inflammatory Pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide g...
- Nitrate and nitrite in biology, nutrition and therapeutics.
- Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell Disease.
- Storage lesion in banked blood due to hemolysis-dependent disruption of nitric oxide homeostasis.
- Nitrite therapy after cardiac arrest reduces reactive oxygen species generation, improves cardiac and neurological function, and enhances survival via reversible inhib...
- Vasculopathy in sickle cell Disease: Biology, pathophysiology, genetics, translational medicine, and new research directions.
- Prospective echocardiography assessment of Pulmonary hypertension and its potential etiologies in children with sickle cell disease.
- Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism.
- Nitrite as regulator of hypoxic signaling in mammalian physiology.
- Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response.
- Bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation.
- Updated clinical classification of Pulmonary hypertension.
Schools
University of Miami School of Medicine
Oregon Health Sciences University
National Institute Of Health
University Of Washington Med Center
Warren G Magnuson Clinical Center
Procedures Preformed
- Bronchoscopy
- Ventilation Management
Conditions Treated
- Alkalosis
- Asthma
- Bronchitis
- Chronic Pulmonary Heart Diseases (incl. Pulmonary Hypertension)
- View All
Doctors Specialties
- Critical Care Medicine
- Pulmonology
- Internal Medicine
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Coventry Health America PPO
- First Health (Coventry Health Care) PPO
- Highmark Blue Cross Blue Shield
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
- UPMC PPO
Awards
- CMS Meaningful Use Stage 1 Certification
- Elected Member
Education
-
National Institutes of Health Clinical Center -
University of Washington -
Oregon Health & Science University -
University of Miami Miller School of Medicine
Hospital
-
UPMC Presbyterian Shadyside
Drug Facts
| NPI NUMBER | 1790997666 | |
| NPPES Provider LastName | GLADWIN | |
| NPPES Provider FirstName | MARK | |
| NPPES Provider ZIPCode | 208920001 | |
| NPPES Provider State | MD | |
| Specialty Description | Pulmonary Disease | |
| Total Claim Count | 12.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1790997666 |
| Last Name Of The Provider | GLADWIN |
| First Name Of The Provider | MARK |
| View All |
Similar Doctors
|
|
Dr. Timothy R. Hauser, MD |
|
|
Dr. John R. Benjamin, MD |
|
|
Dr. Amirali Nader, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Ryan D. Haley, MD |
|
|
Dr. Janet M. Jones, MD |
|
|
Dr. Rahim A. Remtulla, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Roy E. Fried, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Joseph Chiu, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Todd M. Wilson, MD
This Doctor is OpenDoctor Recommended.
|