Professor in Pediatrics and Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School
Neurology
Dr. Mark S. Wainwright, MD
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Mark S. Wainwright, MD is an expert in the field of Neurology. He graduated from University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine is ranked 10 in research and 19 in primary care medicine He over the years received 2 awards: "Chicago Magazine: Top Doctors" and "Whos Who in Medicine and Healthcare". Mark Wainwright is also a published physician. He has 64 publication published. The most recent publication is: Apoptosis induction by different pathways with methylene blue derivative and light from mitochondrial sites in V79 cells. He accepts Medicare.
Publications
- Pediatric neurocritical care in the 21st century: from empiricism to evidence.
- Thrombin decreases expression of the glutamate transporter GLAST and inhibits glutamate uptake in primary cortical astrocytes via the Rho kinase pathway.
- A Treatable Metabolic Cause of Encephalopathy: Cobalamin C Deficiency in an 8-Year-Old Male.
- Pathophysiology and Management of Moderate and Severe Traumatic Brain Injury in Children.
- Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV.
- Neurogenic pulmonary edema and acute respiratory distress syndrome in a healthy child with febrile status epilepticus.
- Nonconvulsive Seizures Are Common in Children Treated With Extracorporeal Cardiac Life Support*
- Symptomatic cerebral vasospasm following resection of a medulloblastoma in a child.
- Liver transplantation followed by allogeneic hematopoietic stem cell transplantation for atypical mevalonic aciduria.
- Pilot Study of the Association of the DDAH2 -449G Polymorphism with Asymmetric Dimethylarginine and Hemodynamic Shock in Pediatric Sepsis.
- Common data elements for pediatric traumatic brain injury: recommendations from the working group on demographics and clinical assessment.
- Unusual Case of Relapsing and Remitting Rash With Progressive Motor Sensory Neuropathy and Spinal Cord Atrophy.
- Mild Stretch-Induced Injury Increases Susceptibility to Interleukin-1?-Induced Release of Matrix Metalloproteinase-9 from Astrocytes.
- Successful Treatment of Recurrent Basilar Artery Occlusion with Intra-Arterial Thrombolysis and Vertebral Artery Coiling in a Child.
- Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen-activated protein kinase.
- Ictal asystole and anti-N-methyl-D-aspartate receptor antibody encephalitis.
- Albumin activates the canonical TGF receptor-smad signaling pathway but this is not required for activation of astrocytes.
- Abnormal Neuroimaging is Associated with Early In-Hospital Seizures in Pediatric Abusive Head Trauma.
- Minozac treatment prevents increased seizure susceptibility in a mouse "two-hit" model of closed skull traumatic brain injury and electroconvulsive shock-ind...
- Acquired microcephaly, regression of milestones, mitochondrial dysfunction, and episodic rigidity in a 46,XY male with a de novo MECP2 gene mutation.
- A rapid murine coma and behavior scale for quantitative assessment of murine cerebral malaria.
- Neurological complications of respiratory syncytial virus infection: case series and review of literature.
- Human herpes virus 6B: a possible role in Epilepsy?
- Pediatric endocarditis and stroke: a single-center retrospective review of seven cases.
- Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation.
- Mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathway.
- MLCK210 gene knockout or kinase inhibition preserves lung function following endotoxin-induced lung injury in mice.
- Association of apolipoprotein E genotype and cerebral palsy in children.
- Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats.
- Increased susceptibility of S100B transgenic mice to perinatal hypoxia-ischemia.
- L-carnitine reduces brain injury after hypoxia-ischemia in newborn rats.
- Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment.
- Pharmacological correction of hypothermic P(50) shift does not alter outcome from focal cerebral ischemia in rats.
- The temporal version of the pediatric sepsis biomarker risk model.
- Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model.
- Selective head cooling for the treatment of neurologic complications of acute liver failure in a newborn with disseminated herpes infection.
- Regional dendritic and spine variation in human cerebral cortex: a quantitative golgi study.
- Identifying apoptotic cells with the 3-hydroxyflavone derivative F2N12S, a ratiometric fluorescent small molecule probe selective for plasma membranes: a possible gene...
- Real-time imaging of bacteria in living mice using a fluorescent dye.
- Apoptosis induction by different pathways with methylene blue derivative and light from mitochondrial sites in V79 cells.
- A study of photobactericidal activity in the phenothiazinium series.
- Biodistribution of a methylene blue derivative in tumor and normal tissues of rats.
- Photobactericidal activity of methylene blue derivatives against vancomycin-resistant Enterococcus spp.
- Primary structure of the human platelet serotonin 5-HT2A receptor: identify with frontal cortex serotonin 5-HT2A receptor.
- Common data elements for traumatic brain injury: recommendations from the interagency working group on demographics and clinical assessment.
- Autistic children and their first-degree relatives: relationships between serotonin and norepinephrine levels and intelligence.
- Platelet 5-HT2 serotonin receptor binding sites in autistic children and their first-degree relatives.
- A 2-year-old boy with fever and altered mental status.
- Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties.
- Standardizing data collection in traumatic brain injury.
- Three children with a syndrome of obesity and overgrowth, atypical psychosis, and seizures: a problem in neuropsychopharmacology.
- Human herpesvirus 6 limbic encephalitis after stem cell transplantation.
- Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor.
- DAPK catalytic activity in the hippocampus increases during the recovery phase in an animal model of brain hypoxic-ischemic injury.
- p21ras activation following hypoxia-ischemia in the newborn rat brain is dependent on nitric oxide synthase activity but p21ras does not contribute to neurologic injury.
- The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain.
- An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury.
- Tetrahydrobiopterin and nitric oxide synthase dimer levels are not changed following hypoxia-ischemia in the newborn rat.
- A nitric oxide donor reduces brain injury and enhances recovery of cerebral blood flow after hypoxia-ischemia in the newborn rat.
- Albumin activates astrocytes and microglia through mitogen-activated protein kinase pathways.
- Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a ''two-hit'' seiz...
- Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome ...
- Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury.
Schools
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
Conditions Treated
- Ataxia
- Concussion
- Convulsions
- Dystonia
- View All
Doctors Specialties
- Pediatric Neurology
- Neurology
Accepted Insurances
- Aetna HMO
- Blue Card PPO
- Blue Cross Blue Shield of Illinois PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Coventry Health Care of Illinois PPO
- Health and Life PPO
- Platinum PPO
- Coventry Health Care of Missouri PPO
- First Health (Coventry Health Care) PPO
- HealthLink PPO
- Choice Care PPO
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Sagamore Plus
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Awards
- Chicago Magazine: Top Doctors
- Whos Who in Medicine and Healthcare
Education
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Duke University Hospital -
University of Chicago Pritzker School of Medicine
Hospital
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Lurie Children's Hospital of Chicago -
Northwestern Memorial Hospital -
Ann & Robert H. Lurie Children?
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